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Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 Proteins (PSMC3)

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. Additionally we are shipping PSMC3 Antibodies (92) and PSMC3 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PSMC3 19182 O88685
Rat PSMC3 PSMC3 29677 Q63569
PSMC3 5702 P17980
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Top PSMC3 Proteins at antibodies-online.com

Showing 8 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$721.60
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$3,120.33
Details
Yeast Schizosaccharomyces pombe His tag   1 mg Log in to see 56 to 66 Days
$3,224.83
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$904.80
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PSMC3 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
, ,

More Proteins for Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3) Interaction Partners

Horse (Equine) Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3) interaction partners

  1. The equine homologues of OS-9 (show OS9 Proteins) and PSMC3 were cloned and their interactions with equine infectious anemia virus S2 protein confirmed using co-immunoprecipitation assays.

Human Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3) interaction partners

  1. These data suggest the existence of a negative feedback loop involving Akt/PKB (show AKT1 Proteins) that might act as a sensor to modulate TBP-1 levels in proliferating cells.

  2. 19S ATPase S6b (S6'/TBP1) binds CIITApIV in an S6a-dependent fashion and has effects similar to S6a on CIITApIV histone acetylation.

  3. role in E3 ubiquitin ligase (show MUL1 Proteins) function of the von Hippel-Lindau protein (show VHLL Proteins)

  4. molecular modeling of DNA:TATA element binding protein (TBP (show TBP Proteins)) interactions after treatment with 2-Chloro-2'-deoxyadenosine

  5. Tat-binding protein-1 binds to human ARF tumor suppressor and has a role in control of cell proliferation

  6. In normal cells, unmodified S12 (show HTR1B Proteins) associates with the 26S proteasome (show Psmd4 Proteins), while modified S12 (show HTR1B Proteins)-M does not.

  7. The stabilization effect exerted by TBP-1 requires an intact N-terminal 39 amino acids in ARF and occurs independently from N-terminal ubiquitination of the protein.

  8. findings suggest that a component of 19S regulatory particles directly binds AR and might participate in AR-mediated transcriptional activation in cooperation with TBPIP (show PSMC3IP Proteins).

Cow (Bovine) Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3) interaction partners

  1. reveal critical roles of COOH termini of Rpt subunits of PA700 in the assembly and activation of eukaryotic 26 S proteasome[PA700 proteasome activator ]

PSMC3 Protein Profile

Protein Summary

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9.

Gene names and symbols associated with PSMC3

  • proteasome (prosome, macropain) 26S subunit, ATPase, 3 (psmc3)
  • proteasome (prosome, macropain) 26S subunit, ATPase, 3 (PSMC3)
  • 26S protease regulatory subunit 6A (HCAG_00069)
  • 26S protease regulatory subunit 6A (BBOV_IV004580)
  • 26S protease regulatory subunit 6A (GL50803_4365)
  • 26S protease regulatory subunit 6A (EDI_316920)
  • 26S protease regulatory subunit 6a (CpipJ_CPIJ006888)
  • 26S protease regulatory subunit 6a (CpipJ_CPIJ006889)
  • 26S protease regulatory subunit 6a (CpipJ_CPIJ010864)
  • 26S protease regulatory subunit 6A (CpipJ_CPIJ017726)
  • 26S protease regulatory subunit 6A (CGB_M2140W)
  • 26S protease regulatory subunit 6A (prs6a)
  • 26S protease regulatory subunit 6A (psmC3)
  • proteasome (prosome, macropain) 26S subunit, ATPase 3 (Psmc3)
  • 23.m06430 protein
  • DDBDRAFT_0186002 protein
  • DDBDRAFT_0232967 protein
  • DDB_0186002 protein
  • DDB_0232967 protein
  • MGC89608 protein
  • NV15940 protein
  • PSMC3 protein
  • psmc3-b protein
  • TBP-1 protein
  • TBP1 protein
  • tbp10 protein
  • wu:fb39a02 protein
  • zgc:86713 protein

Protein level used designations for PSMC3

proteasome (prosome, macropain) 26S subunit, ATPase, 3 , proteasome 26S ATPase subunit 3 , 26S protease regulatory subunit 6A , 26S protease regulatory subunit 6A-like , 26S protease regulatory subunit 6a , 26S proteasome ATPase 3 subunit , TAT-binding protein 1 , 26S proteasome AAA-ATPase subunit RPT5 , Tat binding protein 1 , proteasome 26S subunit ATPase 3 , TBP-1 , spermatogenic cell/sperm-associated TAT-binding protein homolog SATA , 26S protease regulatory subunit 6A-B , 26S proteasome AAA-ATPase subunit RPT5-B , TAT-binding protein 10 , TBP-10 , proteasome 26S subunit ATPase 3-B , Tat-binding protein 1 , human immunodeficiency virus tat transactivator binding protein-1 , proteasome subunit P50

GENE ID SPECIES
448481 Xenopus (Silurana) tropicalis
451172 Pan troglodytes
713356 Macaca mulatta
100051468 Equus caballus
100115023 Nasonia vitripennis
100221049 Taeniopygia guttata
100354000 Oryctolagus cuniculus
100391982 Callithrix jacchus
100448468 Pongo abelii
100476973 Ailuropoda melanoleuca
100512454 Sus scrofa
100551003 Meleagris gallopavo
5450967 Ajellomyces capsulatus NAm1
5478621 Babesia bovis T2Bo
5698901 Giardia lamblia ATCC 50803
5883778 Entamoeba dispar SAW760
6039270 Culex quinquefasciatus
6039272 Culex quinquefasciatus
6043386 Culex quinquefasciatus
6051503 Culex quinquefasciatus
10186196 Cryptococcus gattii WM276
100195564 Salmo salar
8624588 Dictyostelium discoideum AX4
100607910 Nomascus leucogenys
100637883 Amphimedon queenslandica
19182 Mus musculus
29677 Rattus norvegicus
321947 Danio rerio
379370 Xenopus laevis
423182 Gallus gallus
5702 Homo sapiens
475980 Canis lupus familiaris
508448 Bos taurus
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