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anti-Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 5 (PSMC5) Antibodies

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. Additionally we are shipping PSMC5 Proteins (9) and PSMC5 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PSMC5 19184 P62196
PSMC5 5705 P62195
PSMC5 81827 P62198
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Top anti-PSMC5 Antibodies at antibodies-online.com

Showing 10 out of 34 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Caenorhabditis elegans Rabbit Un-conjugated IP, IHC, WB WB Suggested Anti-PSMC5 Antibody Titration: 1.25ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate Sample Type: 4. rat brain extract (80ug) Primary Antibody Dilution: 2ug/ml Secondary Antibody: IRDye 800CW goat anti-rabbit from Li-COR Bioscience Secondary Antibody Dilution: 1: 20,000 Image Submitted by: Yuzhi Chen University of Arkansas for Medical Science 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed A549, using PSMC5, antibody at 1:200 dilution. WB Image PSMC5 antibody detects PSMC5 protein by Western blot analysis. A. 30 µg PC-12 whole cell lysate/extract 10 % SDS-PAGE PSMC5 antibody , dilution: 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated DB, ICC, WB Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.01% Triton-X100 in PBS. The cells were immunostained with anti-PSMC5 antibody. 50 μg Log in to see 7 to 9 Days
$285.71
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Cow Chicken Un-conjugated WB 0.05 mg Log in to see 2 to 3 Days
$446.88
Details
Mouse Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using PSMC5 antibody. Immunofluorescence analysis of MCF7 cell using PSMC5 antibody. Blue: DAPI for nuclear staining. 100 μL Log in to see 9 Days
$302.50
Details
Human Mouse Un-conjugated DB, ICC, WB   50 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated WB Western Blot showing PSMC5 antibody used at a concentration of 1-2 ug/ml to detect its target protein. 100 μg Log in to see 7 to 9 Days
$388.93
Details
Human Rabbit Un-conjugated IF   50 μL Log in to see 8 to 10 Days
$390.50
Details

PSMC5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine)
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Human , , ,
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Rat (Rattus)
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Top referenced anti-PSMC5 Antibodies

  1. Caenorhabditis elegans (C. elegans) Polyclonal PSMC5 Primary Antibody for IP, IHC - ABIN2780449 : Inoue, Kon, Ajima, Ohkura, Tani, Yokota, Sutoh: MYO18B interacts with the proteasomal subunit Sug1 and is degraded by the ubiquitin-proteasome pathway. in Biochemical and biophysical research communications 2006 (PubMed)

More Antibodies against PSMC5 Interaction Partners

Mouse (Murine) Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 5 (PSMC5) interaction partners

  1. Study shows that chronic exposure to cocaine alters the nuclear levels of PSMC5, an ATPase (show DNAH8 Antibodies)-containing subunit of the 19S proteasomal complex, in the nucleus accumbens and that PSMC5 in turn controls behavioral responses to cocaine.

  2. These results imply that a deficiency in 19S Rpt6 may be partially related to the MPTP (show PTPN2 Antibodies)-induced increase in alpha-synuclein (show SNCA Antibodies) in the striatum. (19S Rpt6)

  3. Caspase-3 (show CASP3 Antibodies) cleaves specific 19 S proteasome subunits in skeletal muscle stimulating proteasome activity

Human Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 5 (PSMC5) interaction partners

  1. results demonstrate that PSMC5 is a new and important player involved in regulating ERK1/2 (show MAPK1/3 Antibodies) signal transmission through the remodeling of Shoc2 (show SHOC2 Antibodies) scaffold complex in a spatially-defined manner.

  2. Our data suggest that PSMC5 facilitates the damaging effects of radiation in radiation-responsive H460 cancer cells and therefore may serve as a prognostic indicator for radiotherapy and molecular targeted therapy in lung cancer patients.

  3. TRIP-1 regulates fibroblast acquisition of phenotype and function associated with myofibroblasts.

  4. gamma-aminobutyric acidB receptor proteasomal degradation is mediated by the interaction of the GABAB2 C terminus with the proteasomal ATPase (show DNAH8 Antibodies) Rtp6 and regulated by neuronal activity

  5. Rpt6 interacts directly with CKIP-1 (show PLEKHO1 Antibodies) and promotes the turnover of Smurf1 (show SMURF1 Antibodies).

  6. Sug1 plays a critical role in transcription of MHC class I, and the MHC class II-like molecules, HLA-DM and HLA-DO.

  7. Caspase-3 (show CASP3 Antibodies) cleaves specific 19 S proteasome subunits in skeletal muscle stimulating proteasome activity

  8. Findings show that Sug1 is crucial for regulating histone H3K4me3 and H3R17me2 at the cytokine inducible MHC-II and CIITA (show CIITA Antibodies) promoters.

  9. SUG1 has a role in ubiquitin/proteasome-mediated degradation of estrogen receptors

  10. Proteasome dysfunction by a proteasome inhibitor or siRNA-mediated knock-down of Sug1 caused the up-regulation of MYO18B (show MYO18B Antibodies) protein and MYO18B (show MYO18B Antibodies) was polyubiquitinated in vivo.

PSMC5 Antigen Profile

Protein Summary

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PSMC5

  • protease (prosome, macropain) 26S subunit, ATPase 5 (Psmc5) antibody
  • proteasome (prosome, macropain) 26S subunit, ATPase, 5 (PSMC5) antibody
  • proteasome (prosome, macropain) 26S subunit, ATPase, 5 (psmc5) antibody
  • proteasome (prosome, macropain) 26S subunit, ATPase, 5 (Psmc5) antibody
  • Tat-binding protein 10 (TBP10) antibody
  • XSUG1 protein (psmc5) antibody
  • mSUG1 antibody
  • p45 antibody
  • p45/SUG antibody
  • PSMC5 antibody
  • S8 antibody
  • sug-1 antibody
  • Sug1 antibody
  • tbp10 antibody
  • TRIP1 antibody
  • wu:fa14g03 antibody
  • wu:fb23a11 antibody
  • xsug1 antibody
  • zgc:92464 antibody

Protein level used designations for PSMC5

26S protease regulatory subunit 8 , 26S proteasome AAA-ATPase subunit RPT6 , p45/SUG , proteasome 26S subunit ATPase 5 , proteasome subunit p45 , MSUG1 protein , Tat-binding protein homolog 10 , proteasome 26S ATPase subunit 5 , thyroid hormone receptor-interacting protein 1 , thyroid receptor interactor 1 , TRIP1 , for proteasomal ATPase (SUG1) , peptidase (prosome, macropain) 26S subunit, ATPase 5 , protease (prosome, macropain) 26S subunit, ATPase 5 , proteasomal ATPase (SUG1) , proteasome p45/SUG , 26S protease subunit , TAT-binding protein homolog 10 , SUG1 homolog

GENE ID SPECIES
19184 Mus musculus
5705 Homo sapiens
445285 Danio rerio
443908 Xenopus laevis
480478 Canis lupus familiaris
282015 Bos taurus
81827 Rattus norvegicus
397043 Sus scrofa
397968 Xenopus laevis
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