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Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 5 Proteins (PSMC5)

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. Additionally we are shipping PSMC5 Antibodies (34) and PSMC5 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PSMC5 19184 P62196
PSMC5 5705 P62195
PSMC5 81827 P62198
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Top PSMC5 Proteins at antibodies-online.com

Showing 9 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast REACT_Hornworm His tag   1 mg Log in to see 56 to 66 Days
$3,113.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,122.17
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$3,122.17
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,122.17
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$3,296.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PSMC5 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,
Rat (Rattus)

More Proteins for Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 5 (PSMC5) Interaction Partners

Mouse (Murine) Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 5 (PSMC5) interaction partners

  1. Study shows that chronic exposure to cocaine alters the nuclear levels of PSMC5, an ATPase-containing subunit of the 19S proteasomal complex, in the nucleus accumbens and that PSMC5 in turn controls behavioral responses to cocaine.

  2. These results imply that a deficiency in 19S Rpt6 may be partially related to the MPTP-induced increase in alpha-synuclein in the striatum. (19S Rpt6)

  3. Caspase-3 (show CASP3 Proteins) cleaves specific 19 S proteasome subunits in skeletal muscle stimulating proteasome activity

Human Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 5 (PSMC5) interaction partners

  1. results demonstrate that PSMC5 is a new and important player involved in regulating ERK1/2 signal transmission through the remodeling of Shoc2 (show SHOC2 Proteins) scaffold complex in a spatially-defined manner.

  2. Our data suggest that PSMC5 facilitates the damaging effects of radiation in radiation-responsive H460 cancer cells and therefore may serve as a prognostic indicator for radiotherapy and molecular targeted therapy in lung cancer patients.

  3. TRIP-1 regulates fibroblast acquisition of phenotype and function associated with myofibroblasts.

  4. gamma-aminobutyric acidB receptor proteasomal degradation is mediated by the interaction of the GABAB2 C terminus with the proteasomal ATPase Rtp6 and regulated by neuronal activity

  5. Rpt6 interacts directly with CKIP-1 (show PLEKHO1 Proteins) and promotes the turnover of Smurf1 (show SMURF1 Proteins).

  6. Sug1 plays a critical role in transcription of MHC class I, and the MHC class II-like molecules, HLA-DM and HLA-DO.

  7. Caspase-3 (show CASP3 Proteins) cleaves specific 19 S proteasome subunits in skeletal muscle stimulating proteasome activity

  8. Findings show that Sug1 is crucial for regulating histone H3K4me3 and H3R17me2 at the cytokine inducible MHC-II and CIITA (show CIITA Proteins) promoters.

  9. SUG1 has a role in ubiquitin/proteasome-mediated degradation of estrogen receptors

  10. Proteasome dysfunction by a proteasome inhibitor or siRNA-mediated knock-down of Sug1 caused the up-regulation of MYO18B protein and MYO18B was polyubiquitinated in vivo.

PSMC5 Protein Profile

Protein Summary

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PSMC5

  • protease (prosome, macropain) 26S subunit, ATPase 5 (Psmc5)
  • proteasome (prosome, macropain) 26S subunit, ATPase, 5 (PSMC5)
  • proteasome (prosome, macropain) 26S subunit, ATPase, 5 (psmc5)
  • proteasome (prosome, macropain) 26S subunit, ATPase, 5 (Psmc5)
  • Tat-binding protein 10 (TBP10)
  • XSUG1 protein (psmc5)
  • mSUG1 protein
  • p45 protein
  • p45/SUG protein
  • PSMC5 protein
  • S8 protein
  • sug-1 protein
  • Sug1 protein
  • tbp10 protein
  • TRIP1 protein
  • wu:fa14g03 protein
  • wu:fb23a11 protein
  • xsug1 protein
  • zgc:92464 protein

Protein level used designations for PSMC5

26S protease regulatory subunit 8 , 26S proteasome AAA-ATPase subunit RPT6 , p45/SUG , proteasome 26S subunit ATPase 5 , proteasome subunit p45 , MSUG1 protein , Tat-binding protein homolog 10 , proteasome 26S ATPase subunit 5 , thyroid hormone receptor-interacting protein 1 , thyroid receptor interactor 1 , TRIP1 , for proteasomal ATPase (SUG1) , peptidase (prosome, macropain) 26S subunit, ATPase 5 , protease (prosome, macropain) 26S subunit, ATPase 5 , proteasomal ATPase (SUG1) , proteasome p45/SUG , 26S protease subunit , TAT-binding protein homolog 10 , SUG1 homolog

GENE ID SPECIES
19184 Mus musculus
5705 Homo sapiens
445285 Danio rerio
443908 Xenopus laevis
480478 Canis lupus familiaris
282015 Bos taurus
81827 Rattus norvegicus
397043 Sus scrofa
397968 Xenopus laevis
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