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Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with psmg2 (By similarity). Additionally we are shipping PSMG1 Antibodies (49) and many more products for this protein.
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RNA-seq evidence of biallelic expression of PSMG1 and 10 neighboring genes in at least one primary human tissue tested indicates that the expression of PSMG1 is uncoupled from the control of the maternally inherited 5mCpG imprints at the WRB (show WRB Proteins) differentially methylated region (DMR (show WDR20 Proteins)) in disomic controls or trisomy (Down syndrome) individuals.
PSMG1 mutation is associated with Crohn's disease.
Data show that an additive gene-gene interaction involving TLR4 (show TLR4 Proteins), PSMG1, TNFRSF6B (show TNFRSF6B Proteins) and IRGM (show IRGM Proteins) was identified with CD.
PSMG1 gene expression is increased in classic variant of papillary thyroid carcinoma.
The DSCR2 protein is associated with the endoplasmic reticulum; it is not an integral membrane protein and it is maintained on the cytoplasmic side of the ER by indirect interaction with the ER membrane or with another protein.
Further, the results of intracellular localization studies and membrane fractionation assays indicate that DSCR2 is targeted to a cytoplasmic compartment as a soluble form.
two chaperones, designated proteasome assembling chaperone-1 (PAC1) and PAC2 (show PSMG2 Proteins), form a heterodimer and are involved in the maturation of mammalian 20S proteasomes
DSCR2 was found to interact with PPARbeta (show PPARD Proteins) and to inhibit it.
Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with psmg2 (By similarity).
Down syndrome critical region gene 2
, Down syndrome critical region protein 2
, proteasome assembly chaperone 1
, proteasome (prosome, macropain) assembly chaperone 1
, Proteasome assembly chaperone 1
, Down syndrome critical region gene 2, isoform 1
, chromosome 21 leucine-rich protein
, leucine rich protein C21-LRP
, proteasome assembling chaperone 1
, Down syndrome critical region homolog 2
, down syndrome critical region protein 2 homolog
, proteasome assembly chaperone 1-like