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PRMT1 encodes a member of the protein arginine N-methyltransferase (PRMT) family. Additionally we are shipping PRMT1 Antibodies (142) and PRMT1 Proteins (29) and many more products for this protein.
IFNgamma induced PPAR gamma coactivator-1 alpha (PGC-1alpha (show PPARGC1A ELISA Kits)) positively regulated RIG-I (show DDX58 ELISA Kits); with PRMT-1 and G9a (show EHMT2 ELISA Kits) affecting PGC-1alpha (show PPARGC1A ELISA Kits) in a counter-regulatory manner.
PRMT1 inhibition prevents gastric cancer progression by downregulating eIF4E (show EIF4E ELISA Kits) and targeting type II PRMT5 (show PRMT5 ELISA Kits).
RALY (show RALY ELISA Kits) promotes Protein Arginine Methyltransferase 1 alternatively spliced isoform v2 relative expression and metastatic potential in breast cancer cells
the two structural homologs FAM98A and FAM98B included in a novel complex with DDX1 (show DDX1 ELISA Kits) and C14orf166 are required for PRMT1 expression in colorectal cancer cell lines
Maintenance of the progenitors thus requires cooperation by PRMT1 and CSNK1a1 (show CSNK1A1 ELISA Kits) to sustain proliferation gene expression and suppress premature differentiation driven by GRHL3 (show GRHL3 ELISA Kits)
PRMT1 methylates Nrf2 (show GABPA ELISA Kits) protein at a single residue of arginine 437, both in vitro and in vivo. This leads to a moderate increase of its DNA-binding activity and transactivation, which subsequently protects cells against the tBHP-induced glutathione depletion and cell death.
Our data suggest that miR (show MLXIP ELISA Kits)-19a and PRMT1 might be novel indicators of asthma and present new disease-specific therapeutic targets to reduce airway wall remodeling and inflammation in asthmatic patients
The PRMT1 active site residues, Met48 and His293, have been determined to play a key role in dictating product specificity, as: (1) the single mutation of Met48 to Phe enabled PRMT1 to generate MMA (show MMD ELISA Kits), ADMA, and a limited amount of SDMA; (2) the single mutation of His293 to Ser (show SIGLEC1 ELISA Kits) formed the expected MMA (show MMD ELISA Kits) and ADMA products only; (3) the double mutant H293S-M48F-PRMT1 produced SMDA as the major product with limit amount of SDMA.
This article reviews the current literature from research showing interdependent association between cav1 (show CAV1 ELISA Kits)-PRMT1-SIRT1 (show SIRT1 ELISA Kits) to the outcomes of experimental and clinical research aiming to preserve endothelial function with gene- or pharmaco-therapy. [review]
Increase in HLAB expression was concomitant with increase in HIF-1alpha (show HIF1A ELISA Kits) and decrease in PRMT1 levels.
prmt8 (show PRMT8 ELISA Kits) may play important roles non-overlapping with prmt1 in embryonic and neural development depending on its specific N-terminus.
prmt1 gene is actively and ubiquitously expressed at both RNA and protein levels at the early developmental stages of zebrafish.
PRMT1 functions transiently as a coactivator in thyroid hormone (show PTH ELISA Kits) (T3) receptor (TR)-mediated transcription by enhancing TR-T3 response element binding and further suggest that PRMT1 has tissue-specific roles in regulating the rate of metamorphosis.
Results suggest that part of the type I arginine methyltransferases in brains, mainly PRMT1, are sequestered in an inactive form as they associated with membranes or large subcellular complexes.
Collectively, this study firstly demonstrated that PRMT1 exert podocyte-injury effects in mouse glomerulus through Ang (show ANG ELISA Kits) /ERK (show EPHB2 ELISA Kits) pathway, which reveals a potential therapeutic target for DN.
Low Prmt1 expression is associated with osteosarcoma.
Collectively, the authors propose that Prmt1-dependent facilitation of KCNQ (show KCNQ1 ELISA Kits)-phosphatidylinositol-4,5-bisphosphate interaction underlies the positive regulation of KCNQ (show KCNQ1 ELISA Kits) activity by arginine methylation, which may serve as a key target for prevention of neuronal hyperexcitability and seizures.
Results identify a key molecular mechanism by which the BTG2 (show BTG2 ELISA Kits)-PRMT1 module regulates pre-B cell differentiation and inhibits pre-B cell leukemogenesis.
Data, including data from studies in cells from knockout mice, suggest that Prmt1 activity was necessary for c-Myc (show MYC ELISA Kits) binding to acetyltransferase p300 (show NOTCH1 ELISA Kits) in myeloid cells; Prmt1 inhibition decreases p300 (show NOTCH1 ELISA Kits) recruitment to c-Myc (show MYC ELISA Kits) target promoters and increased Hdac1 (show HDAC1 ELISA Kits) recruitment. [Prmt1, protein arginine N-methyltransferase 1; c-Myc (show MYC ELISA Kits) = Proto-Oncogene (show RAB1A ELISA Kits) Proteins c-myc (show MYC ELISA Kits); Hdac1 (show HDAC1 ELISA Kits) = histone deacetylase 1 (show HDAC1 ELISA Kits)]
PRMT1-dependent regulation of macrophage PPARgamma (show PPARG ELISA Kits) expression contributes to the infection susceptibility in PRMT1 knock-out mice
These findings suggest that arginine methylation by PRMT1 regulates muscle stem cell fate through the Eya1 (show EYA1 ELISA Kits)/Six1 (show SIX1 ELISA Kits)/MyoD (show MYOD1 ELISA Kits) axis.
PRMT1 is necessary for lymphocyte functions in vivo.
The Protein arginine methyltransferase 1 (PRMT1) is involved in multiple cellular functions including proliferation and differentiation and PRMT1 is important for embryonic vascular formation.
This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.
protein arginine N-methyltransferase 1
, protein arginine methyltransferase 1
, protein arginine N-methyltransferase
, HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 2
, heterogeneous nuclear ribonucleoprotein methyltransferase 1-like 2
, histone-arginine N-methyltransferase PRMT1
, interferon receptor 1-bound protein 4
, HMT1 hnRNP methyltransferase-like 2
, histone-arginine N-methyltransferase PRMT1-A
, protein arginine N-methyltransferase 1-A
, heterogeneous nuclear ribonucleoproteins methyltransferase-like 2
, arginine N-methyltransferase 1