Protein Arginine Methyltransferase 1 Proteins (PRMT1)

PRMT1 encodes a member of the protein arginine N-methyltransferase (PRMT) family. Additionally we are shipping PRMT1 Antibodies (142) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PRMT1 3276 Q99873
Rat PRMT1 PRMT1 60421 Q63009
PRMT1 15469 Q9JIF0
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Top PRMT1 Proteins at antibodies-online.com

Showing 10 out of 36 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
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HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 13 to 16 Days
$242.00
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 60 to 71 Days
$2,955.33
Details
HOST_Escherichia coli (E. coli) Human His tag   10 μg Log in to see 15 to 16 Days
$225.00
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HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 4 Days
$385.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
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HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$260.00
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   50 μg Log in to see 2 to 3 Days
$260.00
Details

PRMT1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , ,
, , , , ,
Mouse (Murine) ,
, ,

Top referenced PRMT1 Proteins

  1. Human PRMT1 Protein expressed in HEK-293 Cells - ABIN2729657 : Tikhanovich, Kuravi, Artigues, Villar, Dorko, Nawabi, Roberts, Weinman: Dynamic Arginine Methylation of Tumor Necrosis Factor (TNF) Receptor-associated Factor 6 Regulates Toll-like Receptor Signaling. in The Journal of biological chemistry 2015 (PubMed)

More Proteins for Protein Arginine Methyltransferase 1 (PRMT1) Interaction Partners

Human Protein Arginine Methyltransferase 1 (PRMT1) interaction partners

  1. RALY (show RALY Proteins) promotes Protein Arginine Methyltransferase 1 alternatively spliced isoform v2 relative expression and metastatic potential in breast cancer cells

  2. the two structural homologs FAM98A and FAM98B included in a novel complex with DDX1 (show DDX1 Proteins) and C14orf166 (show C14orf166 Proteins) are required for PRMT1 expression in colorectal cancer cell lines

  3. Maintenance of the progenitors thus requires cooperation by PRMT1 and CSNK1a1 (show CSNK1A1 Proteins) to sustain proliferation gene expression and suppress premature differentiation driven by GRHL3 (show GRHL3 Proteins)

  4. PRMT1 methylates Nrf2 (show GABPA Proteins) protein at a single residue of arginine 437, both in vitro and in vivo. This leads to a moderate increase of its DNA-binding activity and transactivation, which subsequently protects cells against the tBHP-induced glutathione depletion and cell death.

  5. Our data suggest that miR (show MLXIP Proteins)-19a and PRMT1 might be novel indicators of asthma and present new disease-specific therapeutic targets to reduce airway wall remodeling and inflammation in asthmatic patients

  6. The PRMT1 active site residues, Met48 and His293, have been determined to play a key role in dictating product specificity, as: (1) the single mutation of Met48 to Phe enabled PRMT1 to generate MMA (show MMD Proteins), ADMA, and a limited amount of SDMA; (2) the single mutation of His293 to Ser (show SIGLEC1 Proteins) formed the expected MMA (show MMD Proteins) and ADMA products only; (3) the double mutant H293S-M48F-PRMT1 produced SMDA as the major product with limit amount of SDMA.

  7. This article reviews the current literature from research showing interdependent association between cav1 (show CAV1 Proteins)-PRMT1-SIRT1 (show SIRT1 Proteins) to the outcomes of experimental and clinical research aiming to preserve endothelial function with gene- or pharmaco-therapy. [review]

  8. Increase in HLAB expression was concomitant with increase in HIF-1alpha (show HIF1A Proteins) and decrease in PRMT1 levels.

  9. Low expression of PRMT1 is associated with low chemosensitivity in gastric cancer.

  10. PRMT1 is overexpressed in human melanoma, and may regulate tumor growth and metastasis via targeting ALCAM (show ALCAM Proteins).

Zebrafish Protein Arginine Methyltransferase 1 (PRMT1) interaction partners

  1. prmt8 (show PRMT8 Proteins) may play important roles non-overlapping with prmt1 in embryonic and neural development depending on its specific N-terminus.

  2. prmt1 gene is actively and ubiquitously expressed at both RNA and protein levels at the early developmental stages of zebrafish.

Xenopus laevis Protein Arginine Methyltransferase 1 (PRMT1) interaction partners

  1. PRMT1 functions transiently as a coactivator in thyroid hormone (show PTH Proteins) (T3) receptor (TR)-mediated transcription by enhancing TR-T3 response element binding and further suggest that PRMT1 has tissue-specific roles in regulating the rate of metamorphosis.

Pig (Porcine) Protein Arginine Methyltransferase 1 (PRMT1) interaction partners

  1. Results suggest that part of the type I arginine methyltransferases in brains, mainly PRMT1, are sequestered in an inactive form as they associated with membranes or large subcellular complexes.

Mouse (Murine) Protein Arginine Methyltransferase 1 (PRMT1) interaction partners

  1. Low Prmt1 expression is associated with osteosarcoma.

  2. Collectively, the authors propose that Prmt1-dependent facilitation of KCNQ (show KCNQ1 Proteins)-phosphatidylinositol-4,5-bisphosphate interaction underlies the positive regulation of KCNQ (show KCNQ1 Proteins) activity by arginine methylation, which may serve as a key target for prevention of neuronal hyperexcitability and seizures.

  3. Results identify a key molecular mechanism by which the BTG2 (show BTG2 Proteins)-PRMT1 module regulates pre-B cell differentiation and inhibits pre-B cell leukemogenesis.

  4. Data, including data from studies in cells from knockout mice, suggest that Prmt1 activity was necessary for c-Myc (show MYC Proteins) binding to acetyltransferase p300 (show NOTCH1 Proteins) in myeloid cells; Prmt1 inhibition decreases p300 (show NOTCH1 Proteins) recruitment to c-Myc (show MYC Proteins) target promoters and increased Hdac1 (show HDAC1 Proteins) recruitment. [Prmt1, protein arginine N-methyltransferase 1; c-Myc (show MYC Proteins) = Proto-Oncogene (show RAB1A Proteins) Proteins c-myc (show MYC Proteins); Hdac1 (show HDAC1 Proteins) = histone deacetylase 1 (show HDAC1 Proteins)]

  5. PRMT1-dependent regulation of macrophage PPARgamma (show PPARG Proteins) expression contributes to the infection susceptibility in PRMT1 knock-out mice

  6. These findings suggest that arginine methylation by PRMT1 regulates muscle stem cell fate through the Eya1 (show EYA1 Proteins)/Six1 (show SIX1 Proteins)/MyoD (show MYOD1 Proteins) axis.

  7. PRMT1 is necessary for lymphocyte functions in vivo.

  8. The Protein arginine methyltransferase 1 (PRMT1) is involved in multiple cellular functions including proliferation and differentiation and PRMT1 is important for embryonic vascular formation.

  9. A time-dependent decrease in serum and tissue ADMA and increase in mRNA expression of DDAH-1 and PRMT-1 as well as higher rates of mRNA expression of CAT-1 and lower rates of CAT-2A and CAT-2B were found after 8-week MCD diet.

  10. PRMT1 is required for CNS development, especially for oligodendrocyte maturation processes

PRMT1 Protein Profile

Protein Summary

This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.

Gene names and symbols associated with PRMT1

  • protein arginine N-methyltransferase 1 (PRMT1A)
  • protein arginine N-methyltransferase 1 (NCU07459)
  • protein arginine N-methyltransferase 1 (EDI_007800)
  • protein arginine N-methyltransferase 1 (Smp_029240.3)
  • protein arginine methyltransferase 1 (prmt1)
  • protein arginine N-methyltransferase (PRMT1)
  • protein arginine methyltransferase (prmt1)
  • protein arginine methyltransferase 1 (PRMT1)
  • protein arginine methyltransferase 1 (prmt1-a)
  • protein arginine methyltransferase 1 (Prmt1)
  • protein arginine N-methyltransferase 1 (Prmt1)
  • 3E10 protein
  • 6720434D09Rik protein
  • anm1 protein
  • ARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 1A protein
  • ATPRMT1A protein
  • AW214366 protein
  • DDBDRAFT_0183976 protein
  • DDBDRAFT_0235399 protein
  • DDB_0183976 protein
  • DDB_0235399 protein
  • DKFZp459J1326 protein
  • F6F22.30 protein
  • F6F22_30 protein
  • fb39h07 protein
  • hcp1 protein
  • Hrmt1l2 protein
  • ir1b4 protein
  • Mrmt1 protein
  • PRMT1 protein
  • protein arginine methyltransferase 1A protein
  • wu:fb39h07 protein
  • xPRMT1 protein
  • xPRMT1b protein
  • zf1 protein
  • zgc:66201 protein

Protein level used designations for PRMT1

protein arginine N-methyltransferase 1 , protein arginine methyltransferase 1 , protein arginine N-methyltransferase , HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 2 , heterogeneous nuclear ribonucleoprotein methyltransferase 1-like 2 , histone-arginine N-methyltransferase PRMT1 , interferon receptor 1-bound protein 4 , HMT1 hnRNP methyltransferase-like 2 , histone-arginine N-methyltransferase PRMT1-A , protein arginine N-methyltransferase 1-A , heterogeneous nuclear ribonucleoproteins methyltransferase-like 2 , arginine N-methyltransferase 1

GENE ID SPECIES
816486 Arabidopsis thaliana
3880059 Neurospora crassa OR74A
5880968 Entamoeba dispar SAW760
8347013 Schistosoma mansoni
100194598 Salmo salar
5728909 Chlamydomonas reinhardtii
8628232 Dictyostelium discoideum AX4
100052097 Equus caballus
100173232 Pongo abelii
3276 Homo sapiens
321974 Danio rerio
399121 Xenopus laevis
476411 Canis lupus familiaris
520388 Bos taurus
60421 Rattus norvegicus
100286877 Sus scrofa
15469 Mus musculus
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