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anti-Protein C (Inactivator of Coagulation Factors Va and VIIIa) (PROC) Antibodies

PROC encodes a vitamin K-dependent plasma glycoprotein. Additionally we are shipping PROC Proteins (20) and PROC Kits (18) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PROC 25268 P31394
PROC 19123 P33587
PROC 5624 P04070
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Top anti-PROC Antibodies at antibodies-online.com

Showing 10 out of 36 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-PROC Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: MCF7 cell lysate Host: Rabbit  Target Name: PROC  Sample Tissue: Human Adult Placenta  Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Confocal immunofluorescent analysis of PROC Antibody (Center) (ABIN657466) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-Protein C antibody, Western blotting Lane 1: JURKAT Cell Lysate Lane 2: CEM Cell Lysate Lane 3: SMMC Cell Lysate Lane 4: HELA Cell Lysate Anti-Protein C antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated WB Western blot analysis on human plasma using anti-vitamin K-dependent protein C polyclonal antibody.        100 μL Log in to see 9 to 11 Days
$275.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Mouse Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of ES-2 cell lines, using PROC antibody. 200 μL Log in to see 9 Days
$588.50
Details
Human Mouse Un-conjugated WB Western Blot analysis of PROC expression in transfected 293T cell line by PROC MaxPab polyclonal antibody.Lane 1: PROC transfected lysate(50.71 KDa).Lane 2: Non-transfected lysate. 50 μL Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IF, IHC, WB 400 μL Log in to see 6 Days
$457.14
Details

PROC Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)


Mouse (Murine)


Human
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Top referenced anti-PROC Antibodies

  1. Human Polyclonal PROC Primary Antibody for WB - ABIN2776947 : Russell, Wellman, Walley: Protein C rs2069912 C allele is associated with increased mortality from severe sepsis in North Americans of East Asian ancestry. in Human genetics 2008 (PubMed)

More Antibodies against PROC Interaction Partners

Mouse (Murine) Protein C (Inactivator of Coagulation Factors Va and VIIIa) (PROC) interaction partners

  1. These findings reveal a novel biological function and mechanism of the protein C pathway in which protein S and the aPC (show APC Antibodies)-cleaved form of fV are cofactors for anti-inflammatory cell signaling by aPC (show APC Antibodies) in the context of endotoxemia and infection

  2. activated PC-EPCR-PAR1 signaling promotes hematopoietic stem cell retention in bone marrow.

  3. impaired EPCR (show PROCR Antibodies)/protein C-binding interactions not only result in procoagulant and proinflammatory effects, but also impact hematopoiesis

  4. SOD prevents thrombomodulin (show THBD Antibodies) methionine oxidation, promotes protein C activation, and protects against arterial and venous thrombosis in mice.

  5. sPLA2 (show PLA2G2A Antibodies)-V plays a thrombogenic role by impairing the ability of EPCR (show PROCR Antibodies) to promote protein C activation.

  6. Data identify anticoagulant activated protein C as a "metaplastic molecule", capable of shifting the threshold of LTP (show SCP2 Antibodies) towards further potentiation

  7. Histones regulate activated protein C formation in a manner similar to PF4 (show PF4 Antibodies) and suggest heparinoids may be benificial in sepsis.

  8. EPCR (show PROCR Antibodies) and APC (show APC Antibodies) play a limited role in the host response during pulmonary tuberculosis.

  9. Inhibition of the anticoagulant function of activated protein C does not interfere with its protective role during Gram-negative pneumosepsis, suggesting a more prominent role for cytoprotective effects of APC (show APC Antibodies) .

  10. RNA interference of Serpinc1 (show SERPINC1 Antibodies) and/or Proc allows for evaluation of the function of these genes in vivo and provides a novel, controlled mouse model for spontaneous venous thrombosis.

Human Protein C (Inactivator of Coagulation Factors Va and VIIIa) (PROC) interaction partners

  1. Elevated levels of circulating microparticles can play a role in carriers of mild and severe inherited thrombophilia resulting from protein C deficiency.

  2. ApoER2 (show LRP8 Antibodies) contributes cooperatively with endothelial cell protein C receptor (show PROCR Antibodies) and protease activated receptor 1 (show F2R Antibodies) to APC (show APC Antibodies)-initiated endothelial antiapoptotic and barrier protective signaling.

  3. Results show that free activated protein C binds to membrane EPCR (show PROCR Antibodies) in ovarian cancer cells inducing cell migration via MEK (show MAP2K1 Antibodies)-ERK (show EPHB2 Antibodies) and Rho-GTPase (show RACGAP1 Antibodies) pathways. The cancer cells become highly aggressive, and secondary nodules develop because of fibrin inhibition.

  4. Low levels of protein C during pregnancy were not associated with adverse pregnancy outcome.

  5. Report activation of protein C and down-regulation of EPCR (show PROCR Antibodies) in trophobolasts stimulated with TNF-alpha (show TNF Antibodies).

  6. levels of protein C and soluble thrombomodulin (show THBD Antibodies) in critically ill patients with acute kidney injury

  7. Data show the molecular model of the complex of activated protein C (APC (show APC Antibodies)) with alphaVbeta3 integrin obtained by protein-protein docking approach.

  8. Protein C is activated during in vitro thrombolysis.

  9. Results provide evidence that APC (show APC Antibodies) selectively inhibits proliferation and the inflammatory signaling pathways of rheumatoid synovial fibroblasts.

  10. High avidity anti-protein C antibodies by provide marker for a severe thrombotic phenotype in antiphospholipid syndrome.

Cow (Bovine) Protein C (Inactivator of Coagulation Factors Va and VIIIa) (PROC) interaction partners

  1. Activated protein c is a ghrelin (show GHRL Antibodies) endopeptidase.

  2. Activated protein C(APC (show APC Antibodies)) combined with protein S(PS) had significant antithrombotic effect. APC (show APC Antibodies) combined with PS prolonged clotting time. Dependence on APC (show APC Antibodies)-cofactor activity of PS for expression of anticoagulant activity by APC (show APC Antibodies).

PROC Antigen Profile

Protein Summary

This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.

Gene names and symbols associated with PROC

  • protein C (inactivator of coagulation factors Va and VIIIa), a (proca) antibody
  • protein C (inactivator of coagulation factors Va and VIIIa) (PROC) antibody
  • protein C (inactivator of coagulation factors Va and VIIIa) (proc) antibody
  • protein C (inactivator of coagulation factors Va and VIIIa) (LOC100231143) antibody
  • vitamin K-dependent protein C (CpipJ_CPIJ000393) antibody
  • vitamin K-dependent protein C (CpipJ_CPIJ002754) antibody
  • vitamin K-dependent protein C (CpipJ_CPIJ003717) antibody
  • vitamin K-dependent protein C (CpipJ_CPIJ003718) antibody
  • vitamin K-dependent protein C (CpipJ_CPIJ014440) antibody
  • vitamin K-dependent protein C (CpipJ_CPIJ018032) antibody
  • vitamin K-dependent protein C (CpipJ_CPIJ018737) antibody
  • protein C (Proc) antibody
  • APC antibody
  • MGC64425 antibody
  • PC antibody
  • PROC antibody
  • PROC1 antibody
  • si:ch1073-188c16.3 antibody
  • THPH3 antibody
  • THPH4 antibody
  • zgc:63987 antibody

Protein level used designations for PROC

protein C , procl , anticoagulant protein C , vitamin K-dependent protein C , protein C (inactivator of coagulation factors Va and VIIIa) , vitamin K-dependent protein C-like , autoprothrombin IIA , blood coagulation factor XIV , inactivator of coagulation factors Va, VIII , catalytic region , protein C (precursor of vitamin K-dependent serine protease)

GENE ID SPECIES
393327 Danio rerio
395085 Gallus gallus
459593 Pan troglodytes
100302329 Ovis aries
380116 Xenopus laevis
548476 Xenopus (Silurana) tropicalis
100231143 Taeniopygia guttata
100448857 Pongo abelii
6031231 Culex quinquefasciatus
6033948 Culex quinquefasciatus
6035053 Culex quinquefasciatus
6035054 Culex quinquefasciatus
6047546 Culex quinquefasciatus
6052150 Culex quinquefasciatus
6052641 Culex quinquefasciatus
25268 Rattus norvegicus
19123 Mus musculus
5624 Homo sapiens
281428 Bos taurus
101096161 Felis catus
476104 Canis lupus familiaris
100051306 Equus caballus
396954 Sus scrofa
100009223 Oryctolagus cuniculus
699077 Macaca mulatta
Selected quality suppliers for anti-PROC (PROC) Antibodies
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