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Protein Disulfide Isomerase Family A, Member 3 Proteins (PDIA3)

PDIA3 encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. Additionally we are shipping PDIA3 Antibodies (159) and PDIA3 Kits (40) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PDIA3 14827 P27773
PDIA3 2923 P30101
PDIA3 29468 P11598
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Top PDIA3 Proteins at antibodies-online.com

Showing 10 out of 21 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$286.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$668.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Mesocricetus auratus His tag   1 mg Log in to see 56 to 66 Days
$2,509.83
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,358.67
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,358.67
Details
Yeast REACT_Green monkey His tag   1 mg Log in to see 56 to 66 Days
$3,358.67
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$3,358.67
Details

PDIA3 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,
Rat (Rattus)

Top referenced PDIA3 Proteins

  1. Human PDIA3 Protein expressed in Escherichia coli (E. coli) - ABIN666935 : Forster, Mahn, Tsai: Generating an unfoldase from thioredoxin-like domains. in The Journal of biological chemistry 2009 (PubMed)
    Show all 2 references for ABIN666935

More Proteins for Protein Disulfide Isomerase Family A, Member 3 (PDIA3) Interaction Partners

Mouse (Murine) Protein Disulfide Isomerase Family A, Member 3 (PDIA3) interaction partners

  1. These data indicate a synergistic crosstalk between 1alpha,25(OH)2D3 and BMP2 (show BMP2 Proteins) toward osteogenesis and mineral deposition, involving both VDR (show CYP27B1 Proteins) and Pdia3.

  2. ERp57 deficiency causes neuromuscular defects

  3. ERp57 levels are increased in the airway epithelium of asthmatic patients and in mice with allergic airways disease.

  4. Data suggest that regulation of Pdia3 (protein disulfide isomerase associated 3 protein) expression by microRNA-330-5p is important in maintaining hair cycle through regulation of proliferation and migration capability of keratinocytes.

  5. All the growth plate and bone abnormalities, however, become attenuated after the pubertal growth spurt (show BPIFA1 Proteins), when protein synthesis is decelerated and, hence, ERp57 function is less essential.

  6. a Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins)-driven functional role of ENO1 (show ENO1 Proteins) and PDIA3 in alveolar epithelial cell plasticity in lung injury and repair, is reported.

  7. ERp57 regulates thrombosis via multiple targets.

  8. These data suggest the 25D3 -MARRS receptor/PDIA3/ERp57 may contribute to the length of lifespan in mammals.

  9. Pdia3+/- mice exhibit a mild skeletal phenotype characterized by enlarged growth plates, reduced tether and trabecular bone formation, and impaired osteogenic potential of calvarial osteoblasts in vitro.

  10. results suggest that both of PDI and PDIA3 possess Bak (show BAK1 Proteins)-dependent proapoptotic function through inducing mitochondrial outer membrane permeabilization, which provides a new mechanism linking ER chaperone proteins and apoptotic signaling

Human Protein Disulfide Isomerase Family A, Member 3 (PDIA3) interaction partners

  1. Amyotrophic lateral sclerosis-linked PDIA3 mutations disrupt motor neuron connectivity.

  2. These data indicate that the presence of autoantibodies to PDIA3 favors the development of an efficient and specific T-cell response against PDIA3 in colorectal cancer patients.

  3. ERp57 levels are increased in the airway epithelium of asthmatic patients and in mice with allergic airways disease.

  4. LEDGF/p75 (show PSIP1 Proteins) Overexpression Attenuates Oxidative Stress-Induced (show SQSTM1 Proteins) Necrosis and Upregulates the Oxidoreductase ERP57/PDIA3/GRP58 in Prostate Cancer

  5. it is possible that the vimentin (show VIM Proteins) and PDIA3 could be the candidate biomarkers specific to Achyranthes saponin therapy for rheumatoid arthritis in synovial membrane.

  6. ERp57 specifically contributes to peripheral nerve regeneration, whereas its activity is dispensable for the survival of a specific neuronal population of the central nervous system.

  7. Data suggest that regulation of PDIA3 (protein disulfide isomerase associated 3 protein) expression by microRNA-330-5p is important in maintaining hair cycle through regulation of proliferation and migration capability of keratinocytes.

  8. miR148a inhibits the proliferation and promotes paclitaxelinduced apoptosis of ovarian cancer cells, and this may be partly attributed to direct targeting of PDIA3.

  9. results suggested that ER chaperone PDIA3 plays a pivotal role in FFA-induced hepatocyte steatosis and apoptosis.

  10. The sPLA2 (show PLA2G2A Proteins)-hPDI model constitutes a valuable tool to facilitate further insights into this process and into the (patho)physiology of sPLA2s (show PLA2G2D Proteins) in relation to their action intracellularly.

Cow (Bovine) Protein Disulfide Isomerase Family A, Member 3 (PDIA3) interaction partners

  1. PDIA3 may play in the progression of heart failure.

PDIA3 Protein Profile

Protein Summary

This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase\; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.

Gene names and symbols associated with PDIA3

  • zgc:100906 (zgc:100906)
  • protein disulfide-isomerase A3 (Tsp_10062)
  • protein disulfide isomerase family A, member 3 (PDIA3)
  • protein disulfide isomerase associated 3 (Pdia3)
  • protein disulfide isomerase family A, member 3 (Pdia3)
  • 1 protein
  • 25D3-membrane-associated protein
  • 58kDa protein
  • ER60 protein
  • Erp protein
  • ERp57 protein
  • ERp60 protein
  • ERp61 protein
  • grp-58 protein
  • GRP57 protein
  • GRP58 protein
  • HsT17083 protein
  • P58 protein
  • PDI protein
  • PDI-Q2 protein
  • PI-PLC protein
  • Plca protein
  • PLC[a] protein

Protein level used designations for PDIA3

protein disulfide-isomerase A3 , protein disulfide-isomerase A3-like , 58 kDa glucose-regulated protein , 58 kDa microsomal protein , ER protein 57 , ER protein 60 , disulfide isomerase ER-60 , endoplasmic reticulum protein , endoplasmic reticulum resident protein 57 , endoplasmic reticulum resident protein 60 , glucose regulated protein, 58 kDa , p58 , phospholipase C, alpha , endoplasmic reticulum P58 , glucose regulated protein, 58kDa , phospholipase C-alpha , protein disulfide isomerase-associated 3 , ERP60 , ERp57 , glucose regulated protein 58kD , ER-60 protease , ERp60 , HIP-70 , Q-2 , oxidoreductase ERp57 , protein disulfide isomerase associated 3 , glucose regulated protein 58 , 1,25D3-MARRS protein , 1,25D3-membrane-associated, rapid-response steroid-binding protein , 25D3-MARRS protein , glucose regulated thiol oxidoreductase protein , glucose-regulated thiol oxidoreductase 58 kDa protein , rapid-response steroid-binding protein

GENE ID SPECIES
445123 Danio rerio
10905562 Trichinella spiralis
100137432 Papio anubis
14827 Mus musculus
2923 Homo sapiens
281803 Bos taurus
29468 Rattus norvegicus
478279 Canis lupus familiaris
100156204 Sus scrofa
100328685 Oryctolagus cuniculus
100725599 Cavia porcellus
373899 Gallus gallus
100302346 Ovis aries
100174305 Pongo abelii
101097245 Felis catus
100860882 Capra hircus
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