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anti-Protein Interacting With Protein Kinase C, alpha 1 (PICK1) Antibodies

The protein encoded by PICK1 contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). Additionally we are shipping PICK1 Kits (24) and PICK1 Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PICK1 18693  
PICK1 84591 Q9EP80
PICK1 9463 Q9NRD5
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Top anti-PICK1 Antibodies at antibodies-online.com

Showing 10 out of 119 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Western blot analysis of hPRKCABP-C300 (ABIN391109) in HL-60, Jurkat, K562 cell line lysates (35 µg/lane). PRKCABP (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Goat Un-conjugated ELISA, WB ABIN185725 (1µg/ml) staining of mouse brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$326.89
Details
Dog Goat Un-conjugated EIA, WB 20 μg Log in to see 6 to 8 Days
$203.50
Details
Mouse Chicken Un-conjugated ICC, IF, IHC (p), IP, IHC, WB 0.1 mL Log in to see 5 to 7 Days
$381.94
Details
Mouse Goat Un-conjugated ELISA, WB ABIN188575 (1?g/ml) staining of Mouse Brain lysate (35?g protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Western Blot: PICK1 Antibody [ABIN1885753] - Analysis PICK1 in Mouse Brain lysate using this antibody at 1ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 5 to 7 Days
$408.19
Details
Mouse Rabbit Un-conjugated ICC, IF, IP, WB Immunocytochemistry/Immunofluorescence: PICK1 Antibody [ABIN189737] - Immunolocalization of PICK1 in CV1 cells transfected with both PICK1 and mGluR7a. 0.1 mg Log in to see 5 to 7 Days
$408.19
Details
Human Rabbit Un-conjugated WB The anti-PRKCABP Pab (ABIN391108) is used in Western blot to detect PRKCABP in Y79 cell lysate. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of anti-PRKCABP Antibody (C-term) in K562 cell line lysates (35ug/lane). PRKCABP(arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB The anti-PRKCABP Pab is used in Western blot to detect PRKCABP in Y79 cell lysate. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Mouse Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$481.25
Details

PICK1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-PICK1 Antibodies

  1. Mouse (Murine) Polyclonal PICK1 Primary Antibody for ICC, IF - ABIN449250 : Bassan, Liu, Madsen, Armsen, Zhou, Desilva, Chen, Paradise, Brasch, Staudinger, Gether, Irwin, Rosenberg: Interaction between the glutamate transporter GLT1b and the synaptic PDZ domain protein PICK1. in The European journal of neuroscience 2008 (PubMed)
    Show all 4 references for ABIN449250

  2. Mouse (Murine) Polyclonal PICK1 Primary Antibody for ELISA, WB - ABIN188575 : Xu, Sun, Gibson, Henkemeyer: A dual shaping mechanism for postsynaptic ephrin-B3 as a receptor that sculpts dendrites and synapses. in Nature neuroscience 2011 (PubMed)
    Show all 2 references for ABIN188575

  3. Dog (Canine) Polyclonal PICK1 Primary Antibody for EIA, WB - ABIN782997 : Steinberg, Takamiya, Shen, Xia, Rubio, Yu, Jin, Thomas, Linden, Huganir: Targeted in vivo mutations of the AMPA receptor subunit GluR2 and its interacting protein PICK1 eliminate cerebellar long-term depression. in Neuron 2006 (PubMed)

  4. Human Polyclonal PICK1 Primary Antibody for WB - ABIN391109 : Xue, Zhang, Chen, Lin, Shi: PDZ protein mediated activity-dependent LTP/LTD developmental switch at rat retinocollicular synapses. in American journal of physiology. Cell physiology 2010 (PubMed)

  5. Mouse (Murine) Polyclonal PICK1 Primary Antibody for ICC, IF - ABIN189737 : Sakamoto, Seiki: Mint3 enhances the activity of hypoxia-inducible factor-1 (HIF-1) in macrophages by suppressing the activity of factor inhibiting HIF-1. in The Journal of biological chemistry 2009 (PubMed)

More Antibodies against PICK1 Interaction Partners

Mouse (Murine) Protein Interacting With Protein Kinase C, alpha 1 (PICK1) interaction partners

  1. a dual role of PICK1 in regulating macrophage polarization

  2. This study demonstrated that d-serine provent the behavioral deficits in adult Pick1 knockout mice.

  3. PICK1 is an important regulator of P2Y6R (show P2RY6 Antibodies) expression and microglial phagocytosis.

  4. knocking-out PICK1 gene casts the neuroprotection effect by reducing ASICs current and the calcium transients in OGD (show FGFR1 Antibodies)-Rep neuronal cells

  5. ICA1L forms BAR-domain complexes with PICK1 and is crucial for acrosome formation in spermiogenesis.

  6. results indicate that PICK1 is a crucial regulator in glutathione homeostasis and may play important roles in oxidative stress.

  7. In cultured neurons, PICK1 deletion increases surface AMPARs and blocks Abeta42-induced reduction in surface GluA2 (show GRIA2 Antibodies).

  8. This study demonstrated that PICK1 functions in vesicle biogenesis and is necessary to maintain normal vesicle numbers and size.

  9. C-terminal domain of ICA69 (show ICA1 Antibodies) interacts with PICK1 and acts on trafficking of PICK1-PKCalpha (show PKCa Antibodies) complex and cerebellar plasticity.

  10. we found that PICK1's expression in testis rescued the spermatogenic abnormalities and male infertility in Pick1 knockout mice. Our results indicate that the infertility is caused by the lack of PICK1 in the testis rather than in other organs.

Human Protein Interacting With Protein Kinase C, alpha 1 (PICK1) interaction partners

  1. We propose that PICK1 negatively regulates neoplastic infiltration of astrocytic tumors and that manipulation of PICK1 is an attractive possibility for therapeutic intervention

  2. PICK1 domain ACT links PICK1-associated vesicles to a motility factor, likely myosin, but, contrary to previous reports, PICK1 neither binds nor inhibits Arp2 (show ACTR2 Antibodies)/3 complex.

  3. Unlike accessory domains in other BAR domain proteins, the positioning of the PDZ domains is flexible, enabling PICK1 to perform long-range, dynamic scaffolding of membrane-associated proteins.

  4. Data indicate three principal binding modes can account for protein interacting with C-kinase 1 (PICK1) PDZ domains binding specificity.

  5. PICK1 promotes Ago2 (show EIF2C2 Antibodies) localization at endosomal compartments in neuronal dendrites and inhibits Ago2 (show EIF2C2 Antibodies) function in translational repression following neuronal stimulation.

  6. These data indicate that Pick1 is involved in regulating the cell-cell junction in epithelial cells.

  7. C-terminal domain of ICA69 (show ICA1 Antibodies) interacts with PICK1 and acts on trafficking of PICK1-PKCalpha (show PKCa Antibodies) complex and cerebellar plasticity.

  8. Family-based association study failed to observe a statistically significant association for any of the genotyped SNPs in the PICK1 gene and attention-deficit hyperactivity disorder.

  9. PICK1 increases caveolin-mediated endocytosis, ubiquitination and degradation of TGF-beta type I receptor (show TGFBR1 Antibodies).

  10. The binding affinities of all major PICK1 interacting proteins are reported and the effects of PICK1 mutations on these interactions are described.

PICK1 Antigen Profile

Protein Summary

The protein encoded by this gene contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Three transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with PICK1

  • protein interacting with PRKCA 1 (PICK1) antibody
  • protein interacting with C kinase 1 (Pick1) antibody
  • protein interacting with PRKCA 1 (Pick1) antibody
  • PICK antibody
  • PRKCABP antibody

Protein level used designations for PICK1

PRKCA-binding protein , protein kinase C, alpha binding protein , protein kinase C-alpha-binding protein , protein that interacts with C kinase 1 , protein interacting with C kinase 1

GENE ID SPECIES
100055023 Equus caballus
18693 Mus musculus
84591 Rattus norvegicus
9463 Homo sapiens
610191 Canis lupus familiaris
100158107 Sus scrofa
533737 Bos taurus
418030 Gallus gallus
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