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Protein Kinase D1 Proteins (PRKD1)

PRKD1 is a serine/threonine kinase that regulates a variety of cellular functions, including membrane receptor signaling, transport at the Golgi, protection from oxidative stress at the mitochondria, gene transcription, and regulation of cell shape, motility, and adhesion (summary by Eiseler et al., 2009 [PubMed 19329994]).[supplied by OMIM, Nov 2010].. Additionally we are shipping Protein Kinase D1 Antibodies (161) and Protein Kinase D1 Kits (22) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PRKD1 5587 Q15139
PRKD1 18760 Q62101
Rat PRKD1 PRKD1 85421 Q9WTQ1
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Top Protein Kinase D1 Proteins at antibodies-online.com

Showing 9 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Baculovirus infected Insect Cells Human Un-conjugated 5 μg Log in to see 2 to 3 Days
$336.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$739.20
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$774.40
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days
$237.60
Details
HOST_Sf-9 cells Human Un-conjugated   5 μg Log in to see 3 to 4 Days
$571.07
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PRKD1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, ,
Mouse (Murine)
,

More Proteins for Protein Kinase D1 (PRKD1) Interaction Partners

Zebrafish Protein Kinase D1 (PRKD1) interaction partners

  1. cloning and expression analysis of a protein kinase C gene, PKCmu, and its regulation of the promoter region (PKCmu)

  2. PKD1 (show PKD1 Proteins) contributes to the regulation of physiological angiogenesis and lymphangiogenesis during zebrafish development and is essential for tumor angiogenesis.

Human Protein Kinase D1 (PRKD1) interaction partners

  1. PRKD1 Mutation is not associated with Solid Tumors and Leukemias.

  2. Knockdown of PKD1 (show PKD1 Proteins) did not affect NMDAR (show GRIN1 Proteins) internalization but prevented the phosphorylation and inhibition of remaining surface NMDARs and NMDAR (show GRIN1 Proteins)-mediated synaptic functions.

  3. Studies indicate that the loss of protein kinase D PKD1 is thought to promote invasion and metastasis, while PKD2 (show PKD2 Proteins) and upregulated PKD3 (show PRKD3 Proteins) to be positive regulators of proliferation.

  4. it is highly possible that PKD1 (show PKD1 Proteins) plays a critical role in signal transduction from the PKC (show PRRT2 Proteins) pathway to the tyrosine kinase (show TXK Proteins) pathway

  5. Positional mapping of PRKD1, NRP1 (show NELL1 Proteins) and PRDM1 (show PRDM1 Proteins) as novel candidate disease genes in truncus arteriosus

  6. Protein kinase D is increased and activated in lung epithelial cells and macrophages in idiopathic pulmonary fibrosis.

  7. a positive relationship between L1 and pPKD1 in both cultured cerebellar neurons and human cerebellar tissue, suggesting that L1 functions in the modulation of PKD1 (show PKD1 Proteins) phosphorylation.

  8. our results demonstrate that PKD1 (show PKD1 Proteins) signaling plays a cell survival role during early stages of oxidative stress in dopaminergic neurons

  9. Results demonstrate a putative tumor-suppressor function of PKD1 (show PKD1 Proteins) in colon tumorigenesis via modulation of beta-catenin (show CTNNB1 Proteins) functions in cells.

  10. PRKD1 is aberrantly methylated and silenced in its expression in invasive breast cancer.

Mouse (Murine) Protein Kinase D1 (PRKD1) interaction partners

  1. Our studies demonstrate that PKD1 (show PKD1 Proteins)/2 is a key regulator of MVB maturation and exosome secretion, and constitutes a mediator of the DGK alpha (show DGKA Proteins) effect on MVB secretory traffic.

  2. Our results show that AKAP13-PKD1 (show PKD1 Proteins) signaling is critical for transcriptional regulation of key contractile, cell death, and metabolic pathways during the development of compensatory hypertrophy in vivo.

  3. PKD1 (show PKD1 Proteins) acts downstream of TGFalpha and Kras, to mediate formation of ductal structures through activation of the Notch (show NOTCH1 Proteins) pathway.

  4. Results reveal that whereas protein kinase D1 and protein kinase D2 (show PKD2 Proteins) are essential for neuronal polarity, there exists a functional redundancy between the two proteins.

  5. PKD controls synaptic plasticity and learning by regulating actin stability in dendritic spines.

  6. regulatory kinase of eNOS (show NOS3 Proteins) in endothelial cells whose activity orchestrates mammalian vascular tone

  7. Overexpression of constitutively active PKD1 (show PKD1 Proteins) in rodent heart results in dilated cardiomyopathy.

  8. PKD1 (show PKD1 Proteins)-deficient keratinocytes showed an increase in transglutaminase expression and activity, indicating an anti-differentiative role of PKD1 (show PKD1 Proteins). Furthermore, the PKD1 (show PKD1 Proteins)-deficient keratinocytes exhibited decreased proliferation.

  9. a positive relationship between L1 and pPKD1 in both cultured cerebellar neurons and human cerebellar tissue, suggesting that L1 functions in the modulation of PKD1 (show PKD1 Proteins) phosphorylation.

  10. BTK (show BTK Proteins) and protein kinase C mu, that are involved in TLR7 (show TLR7 Proteins)/9-triggered IFN-beta (show IFNB1 Proteins) production in dendritic cells.

Cow (Bovine) Protein Kinase D1 (PRKD1) interaction partners

  1. AngII activates PKD via a mechanism involving Src family kinases and PKC, to underlie increased aldosterone production.

  2. Data indicate that Ser738/742-to-glutamate (show GRIN2A Proteins) protein kinase D mutant increased AngII-induced CREB (show CREB1 Proteins) protein and activating transcription factor 2 (show ATF2 Proteins) phosphorylation, and phospho-CREB (show CREB1 Proteins) binding to the steroidogenic acute regulatory protein (show STAR Proteins) promoter.

  3. These results indicate that PKD is downstream of PLD and suggest that PKD is one of the mechanisms through which PLD promotes aldosterone production in response to AngII in adrenal glomerulosa cells.

  4. PKD mediates acute AngII-induced aldosterone secretion.

  5. Protein kinase D-HDAC5 pathway plays an important role in VEGF regulation of gene transcription and angiogenesis

Protein Kinase D1 (PRKD1) Protein Profile

Protein Summary

PRKD1 is a serine/threonine kinase that regulates a variety of cellular functions, including membrane receptor signaling, transport at the Golgi, protection from oxidative stress at the mitochondria, gene transcription, and regulation of cell shape, motility, and adhesion (summary by Eiseler et al., 2009

Gene names and symbols associated with Protein Kinase D1 Proteins (PRKD1)

  • protein kinase D1 (PRKD1)
  • protein kinase D1 (prkd1)
  • protein kinase D1 (Prkd1)
  • protein kinase D1-like (LOC100356062)
  • MGC83727 protein
  • nPKC-D1 protein
  • nPKC-mu protein
  • PKC protein
  • PKC-MU protein
  • Pkcm protein
  • PKD protein
  • PKD1 protein
  • Prkcm protein
  • PRKD1 protein

Protein level used designations for Protein Kinase D1 Proteins (PRKD1)

protein kinase D1 , protein kinase C, mu , serine/threonine-protein kinase D1-like , nPKC-D1 , nPKC-mu , protein kinase C mu type , protein kinase D , serine/threonine-protein kinase D1 , protein kinase C mu

GENE ID SPECIES
100054964 Equus caballus
447531 Xenopus laevis
452834 Pan troglodytes
557123 Danio rerio
100151704 Xenopus (Silurana) tropicalis
100441363 Pongo abelii
100468927 Ailuropoda melanoleuca
716937 Macaca mulatta
100370448 Saccoglossus kowalevskii
100543370 Meleagris gallopavo
100558587 Anolis carolinensis
100593871 Nomascus leucogenys
5587 Homo sapiens
18760 Mus musculus
85421 Rattus norvegicus
423302 Gallus gallus
609091 Canis lupus familiaris
100174944 Sus scrofa
533270 Bos taurus
100722138 Cavia porcellus
101102016 Ovis aries
100356062 Oryctolagus cuniculus
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