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Protein Kinase D3 Proteins (PRKD3)

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. Additionally we are shipping Protein Kinase D3 Antibodies (108) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PRKD3 5312  
PRKD3 75292 Q8K1Y2
Rat PRKD3 PRKD3 313834  
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Top Protein Kinase D3 Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Baculovirus infected Insect Cells Human Un-conjugated 5 μg Log in to see 2 to 3 Days
$336.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Baculovirus infected Insect Cells Human GST tag 50 μg Log in to see 16 Days
$272.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days
$237.60
Details
HOST_Sf-9 cells Human Un-conjugated   5 μg Log in to see 3 to 4 Days
$571.07
Details

PRKD3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,
Mouse (Murine)

More Proteins for Protein Kinase D3 (PRKD3) Interaction Partners

Human Protein Kinase D3 (PRKD3) interaction partners

  1. Data show that similar to a knockdown of serine/threonine kinase (show TLK2 Proteins) protein kinase D3 (PKD3), treatment with this inhibitor targets all tumorigenic processes in vitro and decreases growth of primary tumors and metastasis in vivo

  2. Studies indicate that the loss of protein kinase D PKD1 is thought to promote invasion and metastasis, while PKD2 (show PKD2 Proteins) and upregulated PKD3 to be positive regulators of proliferation.

  3. Loss of PKD2 (show PKD2 Proteins) enhanced KC proliferative potential while loss of PKD3 resulted in a progressive proliferation defect, loss of clonogenicity and diminished tissue regenerative ability.

  4. for the first time, PKD3 is implicated in the transcription activation of latent HIV-1 provirus, and our results revealed a molecular mechanism of prostratin-induced HIV-1 transcription via PKCepsilon (show PRKCE Proteins)/PKD3/NF-kappaB (show NFKB1 Proteins) signaling pathway.

  5. Activation of PKD2 (show PKD2 Proteins) and further increase of PKD3 activity leads to additional phosphorylation and inhibition of endogenous phosphatase slingshot 1L (show SSH1 Proteins).

  6. PKD3 in TNBC cells provides a molecular connection between the Golgi and endolysosomal compartments to enhance proliferative mTORC1-S6K1 (show RPS6KB1 Proteins) signaling.

  7. PKD3 negatively regulates human airway epithelial barrier formation and integrity through down-regulation of claudin-1 (show CLDN7 Proteins), which is a key component of tight junctions.

  8. PKD3 may contribute to the malignant progression of prostate cancer cells through negative regulation of MMP-7 (show MMP7 Proteins) expression.

  9. PKD3 contributes to the proliferation and malignant growth of androgen-dependent prostate cancer cells in part by upregulating PSA (show PLAG1 Proteins) expression.

  10. these data suggest that PKD2 (show PKD2 Proteins) and PKD3 coordinate to promote prostate cancer cell invasion through p65 NF-kappaB (show NFkBP65 Proteins)- and HDAC1 (show HDAC1 Proteins)-mediated expression and activation of uPA (show PRAP1 Proteins).

Mouse (Murine) Protein Kinase D3 (PRKD3) interaction partners

  1. Erythropoietin (show EPO Proteins) regulates GATA1 (show GATA1 Proteins) through protein kinase D (show PRKD1 Proteins) activation, promoting histone deacetylase 5 (show HDAC5 Proteins) dissociation from GATA1 (show GATA1 Proteins), and subsequent GATA1 (show GATA1 Proteins) acetylation.

  2. These data validate PKD3 as a promising therapeutic target in prostate cancer and shed light on the role of secreted tumor-promoting factors in prostate cancer progression.

  3. PKCnu is an important component of signaling pathways downstream from novel PKC enzymes after B-cell receptor engagement

  4. the catalytic activity of PKD3 may regulate its nuclear import through autophosphorylation and/or interaction with another protein

  5. PKD3 is increasingly expressed in neuronal as well as in the supporting connective tissue and in skeletal muscles

  6. reveal a novel distinction between the exocrine and endocrine cells of the pancreas and further identify PKD3 as a signaling molecule that promotes hormone-stimulated amylase (show AMY Proteins) secretion

Protein Kinase D3 (PRKD3) Protein Profile

Protein Summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members.

Gene names and symbols associated with Protein Kinase D3 Proteins (PRKD3)

  • protein kinase D3 (PRKD3)
  • protein kinase D3 (prkd3)
  • polycystic kidney disease 3 (autosomal dominant) (PKD3)
  • protein kinase D3 (Prkd3)
  • 4930557O20Rik protein
  • 5730497N19Rik protein
  • EPK2 protein
  • nPKC-NU protein
  • PKC-NU protein
  • Pkcnu protein
  • PKD3 protein
  • Prkcn protein
  • PRKD3 protein

Protein level used designations for Protein Kinase D3 Proteins (PRKD3)

protein kinase D3 , serine/threonine-protein kinase D3-like , protein kinase C nu type , protein kinase C, nu , protein kinase EPK2 , protein-serine/threonine kinase , serine/threonine-protein kinase D3 , nPKC-nu

GENE ID SPECIES
459158 Pan troglodytes
709647 Macaca mulatta
100397078 Callithrix jacchus
100438207 Pongo abelii
100466224 Ailuropoda melanoleuca
100077901 Ornithorhynchus anatinus
100563064 Anolis carolinensis
100581692 Nomascus leucogenys
5312 Homo sapiens
23683 Homo sapiens
75292 Mus musculus
313834 Rattus norvegicus
483036 Canis lupus familiaris
100523181 Sus scrofa
100712662 Cavia porcellus
538447 Bos taurus
421478 Gallus gallus
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