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anti-Protein O-Linked Mannose Beta1,2-N-Acetylglucosaminyltransferase (POMGNT1) Antibodies

The protein encoded by POMGNT1 is a type II transmembrane protein that resides in the golgi. Additionally we are shipping Protein O-Linked Mannose Beta1,2-N-Acetylglucosaminyltransferase Proteins (7) and Protein O-Linked Mannose Beta1,2-N-Acetylglucosaminyltransferase Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
POMGNT1 68273 Q91X88
POMGNT1 55624 Q8WZA1
POMGNT1 362567 Q5XIN7
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Top anti-Protein O-Linked Mannose Beta1,2-N-Acetylglucosaminyltransferase Antibodies at antibodies-online.com

Showing 10 out of 16 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB IHC-P Image POMGNT1 antibody detects POMGNT1 protein at cytoplasm in mouse liver by immunohistochemical analysis. Sample: Paraffin-embedded mouse liver. POMGNT1 antibody , diluted at 1:500. IHC-P Image Immunohistochemical analysis of paraffin-embedded Cal27 xenograft , using POMGNT1, antibody at 1:500 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to POMGNT1 on formalin-fixed paraffin-embedded human liver (antibody concentration 3 µg/mL). 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB Mouse Brain; WB Suggested Anti-Pomgnt1 Antibody. . Titration: 1.0 ug/ml. . Positive Control: Mouse Brain; Pomgnt1 antibody - N-terminal region in Mouse Brain cells using Western Blot 50 μg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated ICC, IHC (p), WB   100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB 100 μg Log in to see 8 to 10 Days
$537.17
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to POMGNT1 on formalin-fixed paraffin-embedded human liver. [antibody concentration 3 ug/ml] Western Blot detection against Immunogen (36.52 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC (fp), IF, WB 100 μL Log in to see 6 to 11 Days
$485.71
Details
Human Rabbit Un-conjugated IF (cc), IHC (f), IF, IHC (p), IHC, WB   100 μL Log in to see 6 to 8 Days
$431.20
Details

POMGNT1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine)


Human ,
,
,
Rat (Rattus)


More Antibodies against Protein O-Linked Mannose Beta1,2-N-Acetylglucosaminyltransferase Interaction Partners

Mouse (Murine) Protein O-Linked Mannose Beta1,2-N-Acetylglucosaminyltransferase (POMGNT1) interaction partners

  1. Findings suggest that PomGnT1 promotes GBM progression via activation of beta-catenin (show CTNNB1 Antibodies) and may serve as a prognostic factor for glioma patient survival as well as a novel molecular target for anticancer therapy in malignant glioma.

  2. POMGnT1 gene knockout cause basement membrane disruptions in a mouse model of dystroglycanopathy.

  3. Results describe the effect of altered glycosylation of alpha-dystroglycan caused by inactivation of POMGnT1 in the retina.

  4. classical beta1,2-elongation and beta1,6-GlcNAc branching of O-mannose glycan structures are dependent upon the POMGnT1 enzyme and O-mannosylation is not limited solely to alpha-DG in the brain

  5. POMGnT1 knockout mice were viable but with reduced fertility and variable lifespan

  6. The present study provides the first genetic animal model to further dissect the roles of POMGnT1 in MEB disease.

  7. From these findings, we propose that fukutin (show FKTN Antibodies) forms a complex with POMGnT1 and may modulate its enzymatic activity.

  8. POMGnT1(-/-) muscle showed minimal pathological changes with very low-serum creatine kinase levels, and had normally formed muscle basal lamina, but showed reduced muscle mass, reduced numbers of muscle fibers, and impaired muscle regeneration.

Human Protein O-Linked Mannose Beta1,2-N-Acetylglucosaminyltransferase (POMGNT1) interaction partners

  1. When association tests were applied to data from the Diabetes Heart Study, it found exome variants of POMGNT1 and JAK1 (show JAK1 Antibodies) genes were associated with type 2 diabetes.

  2. POMGNT1 Is Glycosylated by Mucin (show SLC13A2 Antibodies)-Type O-Glycans

  3. study presents clinical, neuroradiological, and POMGNT1 findings in 12 muscle-eye-brain disease patients of Turkish origin from 10 families; suggests a genotype-phenotype correlation

  4. Data indicate that Golgi phosphoprotein 3 (GOLPH3 (show GOLPH3 Antibodies)) binds to and controls the Golgi localization of protein O-linked mannose beta-1,2-N-acetlyglucosaminyltransferase 1 (POMGnT1).

  5. Identification of novel POMGnT1 mutations in Chinese patients with muscle-eye-brain disease.

  6. POMGnT1 point mutations and protein expression are associated with variably severe muscle-eye-brain disease showing that severity of the phenotype does not correlate with protein expression.

  7. Promoter alteration causes transcriptional repression of the POMGNT1 gene in limb-girdle muscular dystrophy type 2O.

  8. This study demonistreated that Intragenic rearrangements in POMGNT1 gene in muscle-eye-brain disease.

  9. these results show that the amino acid sequence affects POMGnT1 activity.

  10. This study gives a comprehensive biochemical evaluation of all clinically relevant POMGnT1 point mutations known to date, which have been linked to muscle-eye-brain disease or similar conditions.

Protein O-Linked Mannose Beta1,2-N-Acetylglucosaminyltransferase (POMGNT1) Antigen Profile

Protein Summary

The protein encoded by this gene is a type II transmembrane protein that resides in the golgi. It participates in O-mannosyl glycosylation, and is specific for alpha linked terminal mannose. Mutations in this gene are associated with muscle-eye-brain (MEB) disease. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with POMGNT1

  • protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase (POMGNT1) antibody
  • protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) (pomgnt1) antibody
  • protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase (pomgnt1) antibody
  • protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase (Pomgnt1) antibody
  • protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) (POMGNT1) antibody
  • protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) (Pomgnt1) antibody
  • 0610016I07Rik antibody
  • 4930467B06Rik antibody
  • gnT-I.2 antibody
  • GNTI.2 antibody
  • GnT I.2 antibody
  • im:7151461 antibody
  • LGMD2O antibody
  • MDDGA3 antibody
  • MDDGB3 antibody
  • MDDGC3 antibody
  • MEB antibody
  • MGAT1.2 antibody
  • POMGNT1 antibody
  • zgc:158130 antibody

Protein level used designations for POMGNT1

protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase , O-linked mannose beta1,2-N-acetylglucosaminyltransferase , protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 , O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 , O-mannosyl N-acetylglucosaminyltransferase , UDP-GlcNAc:alpha-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I.2

GENE ID SPECIES
429097 Gallus gallus
456564 Pan troglodytes
482511 Canis lupus familiaris
495292 Xenopus laevis
571876 Danio rerio
707205 Macaca mulatta
100158594 Xenopus (Silurana) tropicalis
100174367 Pongo abelii
100590586 Nomascus leucogenys
68273 Mus musculus
506551 Bos taurus
55624 Homo sapiens
362567 Rattus norvegicus
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