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anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B) Antibodies

The protein encoded by PPM1B is a member of the PP2C family of Ser/Thr protein phosphatases. Additionally we are shipping Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B Proteins (9) and Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PPM1B 19043 P36993
PPM1B 5495 O75688
PPM1B 24667 P35815
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Top anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B Antibodies at antibodies-online.com

Showing 10 out of 70 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-PPM1B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated EIA, WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Mouse Un-conjugated IHC, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PPM1B (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PPM1B. Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-PPM1B mouse monoclonal antibody. (ABIN2454571) 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PPM1B (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PPM1B. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated ELISA, WB 100 μL Log in to see 7 to 8 Days
$374.00
Details
Human Mouse Un-conjugated FACS, WB HEK293T cells transfected with either RC212918 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-PPM1B antibody (ABIN2454508), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PPM1B (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PPM1B. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, WB HEK293T cells transfected with either RC212918 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-PPM1B antibody (ABIN2454548), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PPM1B (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PPM1B. 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Mouse Un-conjugated FACS, IF, WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated IHC (p), WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB 100 μg Log in to see 8 to 10 Days
$478.50
Details

PPM1B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,
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Top referenced anti-Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B Antibodies

  1. Human Monoclonal PPM1B Primary Antibody for EIA, WB - ABIN302211 : Parvari, Gonen, Alshafee, Buriakovsky, Regev, Hershkovitz: The 2p21 deletion syndrome: characterization of the transcription content. in Genomics 2005 (PubMed)
    Show all 2 references for ABIN302211

  2. Chicken Polyclonal PPM1B Primary Antibody for WB - ABIN2787380 : Xiao, McClatchy, Shukla, Zhao, Chen, Shenoy, Yates, Lefkowitz: Functional specialization of beta-arrestin interactions revealed by proteomic analysis. in Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)

More Antibodies against Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B Interaction Partners

Mouse (Murine) Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B) interaction partners

  1. Ppm1b negatively regulates necroptosis through dephosphorylating Rip3 (show MPRIP Antibodies) in vitro and in vivo.

  2. the phosphatase PPM1B as a novel selective modulator of PPARgamma (show PPARG Antibodies) activity.

  3. Although a non-myristoylated mutation (G2A (show GPR132 Antibodies)) of PPM1A (show PPM1A Antibodies) and PPM1B prevented membrane association, this relocalization did not likely cause the decreased activity towards AMPKalpha (show GRK4 Antibodies).

  4. These observations suggest that relatively high PP2Cbeta expression is specifically required during the early stages of pre-implantation development.

Human Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B) interaction partners

  1. PPM1B interacts with Groucho 4 and is localized to DNA in a Groucho-dependent manner, and phosphatase activity is required for transcriptional silencing.

  2. Results identify PPM1B as a critical regulator of both p38 MAPK (show MAPK14 Antibodies)-dependent and independent senescence pathways during normal cellular aging process.

  3. Cadmium reversed PPM1A (show PPM1A Antibodies)-induced cell cycle arrest and cadmium insensitive PPM1A (show PPM1A Antibodies) mutant rescued cadmium induced cell death.

  4. Protein kinase A activates NF-kappaB (show NFKB1 Antibodies)-mediated transcription by destabilization of PP2Cbeta.

  5. the phosphatase PPM1B as a novel selective modulator of PPARgamma (show PPARG Antibodies) activity.

  6. PPM1B functions as a TBK1 (show TBK1 Antibodies) phosphatase dephosphorylates TBK1 (show TBK1 Antibodies) at serine 172 and terminates TBK1 (show TBK1 Antibodies)-mediated IRF3 (show IRF3 Antibodies) activation and IFNbeta gene expression.

  7. Studies show that Ppm1b plays a multilayered role in regulating the availability and optimal activity of the EKLF (show KLF1 Antibodies) protein in erythroid cells.

  8. results implicate a novel and important role for PP2Cbetal in regulating hPXR activity and CYP3A4 (show CYP3A4 Antibodies) expression by inhibiting or desensitizing signaling pathways that negatively regulate the function of pregnane X receptor (show NR1I2 Antibodies) in liver cells

  9. PP2Cbeta down-regulates cytokine-induced NF-kappaB (show NFKB1 Antibodies) activation by altering IKK (show CHUK Antibodies) activity.

  10. Overexpression of PPM1A (show PPM1A Antibodies) and the related PPM1B greatly reduced Cdk9 (show CDK9 Antibodies) T-loop phosphorylation

Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.

Gene names and symbols associated with PPM1B

  • protein phosphatase 1B, magnesium dependent, beta isoform (Ppm1b) antibody
  • protein phosphatase, Mg2+/Mn2+ dependent, 1B (PPM1B) antibody
  • protein phosphatase, Mg2+/Mn2+ dependent, 1B (Ppm1b) antibody
  • protein phosphatase, Mg2+/Mn2+ dependent, 1B (ppm1b) antibody
  • protein phosphatase, Mg2+/Mn2+ dependent, 1G (PPM1G) antibody
  • pp2c-beta-x antibody
  • Pp2c2 antibody
  • pp2cb antibody
  • pp2cbeta antibody
  • ppc2betax antibody

Protein level used designations for PPM1B

PP2C-beta , protein phosphatase 1B , protein phosphatase 2C isoform beta , protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform , protein phosphatase 2C-like protein , Protein phosphatase type 1B (formely 2C) Mg-dependent beta isoform , Protein phosphatase type 1B (formely 2C), Mg-dependent, beta isoform , protein phosphatase 1B, magnesium dependent, beta isoform , MCPP , PP2C-gamma , magnesium-dependent calcium inhibitable phosphatase , protein phosphatase 1G , protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform , protein phosphatase 2C isoform gamma , protein phosphatase magnesium-dependent 1 gamma

GENE ID SPECIES
19043 Mus musculus
5495 Homo sapiens
24667 Rattus norvegicus
443768 Xenopus laevis
421404 Gallus gallus
474573 Canis lupus familiaris
281995 Bos taurus
100356616 Oryctolagus cuniculus
286880 Bos taurus
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