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The protein encoded by PPM1G is a member of the PP2C family of Ser/Thr protein phosphatases. Additionally we are shipping PPM1G Antibodies (118) and PPM1G Proteins (22) and many more products for this protein.
Nuclear phosphatase PPM1G in cellular survival and neural development.
PPM1G phosphatase directly binds 7SK RNA and the kinase inhibitor Hexim1 (show HEXIM1 ELISA Kits) once P-TEFb (show CCNT1 ELISA Kits) has been released from the 7SK snRNP (show LSM2 ELISA Kits).
Hypermethylation in the 3'-protein-phosphatase-1G (PPM1G) gene locus was associated with alcohol use disorder.
PPM1G inactivates monomeric WWP2 and promotes the assembly of WWP2-WWP1 heterodimeric complex.
PPM1G dephosphorylates the P-TEFb (show CCNT1 ELISA Kits) kinase T loop to disassemble the 7SK snRNP (show LSM2 ELISA Kits).
study has identified protein phosphatase PPM1G as a novel regulator of cap-dependent protein translation by negatively controlling the phosphorylation of 4E-BP1 (show EIF4EBP1 ELISA Kits).
ATM (show ATM ELISA Kits)-dependent downregulation of USP7/HAUSP (show USP7 ELISA Kits) by PPM1G activates p53 (show TP53 ELISA Kits) response to DNA damage
The degradation of p21(WAF1/CIP1 (show CDKN1A ELISA Kits)) induced by PP2Cgamma was mediated in a proteasome-dependent manner.
Protein phosphatase 2C gamma mediates histone dephosphorylation/exchange in response to DNA damage or checkpoint recovery in higher eukaryotes.
PP2Cgamma modulates alternative splicing of specific pre-mRNAs coregulated by YB-1 (show YBX1 ELISA Kits).
an interplay between PPM1G and unrip (show STRAP ELISA Kits) determine compartment-specific phosphorylation patterns, localization, and function of the SMN (show STMN1 ELISA Kits) complex
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression.
, fibroblast growth factor inducible 13
, fibroblast growth factor-inducible protein 13
, protein phosphatase 1C
, protein phosphatase 1G
, protein phosphatase 2C isoform gamma
, protein phosphatase magnesium-dependent 1 gamma
, PP2C, gamma
, protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
, protein phosphatase 2, catalytic subunit, gamma isoform
, protein phosphatase 2C gamma isoform
, magnesium-dependent calcium inhibitable phosphatase
, protein phosphatase 1B