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PPP1R10 encodes a protein with similarity to a rat protein that has an inhibitory effect on protein phosphatase-1 (PP1). Additionally we are shipping Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 10 Proteins (4) and many more products for this protein.
Showing 10 out of 27 products:
Cow (Bovine) Polyclonal PPP1R10 Primary Antibody for IF, WB - ABIN2778807
Lee, Lim, Min, Lee, Kim, Lee, Won, Kwon: Protein phosphatase 1 nuclear targeting subunit is a hypoxia inducible gene: its role in post-translational modification of p53 and MDM2. in Cell death and differentiation 2007
Human Monoclonal PPP1R10 Primary Antibody for IF, WB - ABIN968349
Allen, Kwon, Nairn, Greengard: Isolation and characterization of PNUTS, a putative protein phosphatase 1 nuclear targeting subunit. in The Journal of biological chemistry 1998
PNUTS was a valid target of miR (show MLXIP Antibodies)-383 and was involved in the inhibition of gammaH2AX (show H2AFX Antibodies).
PNUTS inhibits the PP1 (show PPA1 Antibodies)-mediated dephosphorylation of critical substrates, especially retinoblastoma protein, by blocking their binding sites on PP1 (show PPA1 Antibodies).
our studies reveal PNUTS as a novel PTEN (show PTEN Antibodies) regulator and a likely oncogene (show RAB1A Antibodies).
PNUTS is identified as a new and integral component of the DNA damage response involved in DNA repair.
stimulation of PP1 (show PPA1 Antibodies) activity via siRNA mediated knockdown of its interacting protein PNUTS (Phosphatase Nuclear Targeting Subunit) leads to Rb dephosphorylation and apoptosis in cancer cells
mammalian Wdr82 (show WDR82 Antibodies) functions in a variety of cellular processes; PTW/PP1 (show PPA1 Antibodies) phosphatase complex (PNUTS, Tox4 (show TOX4 Antibodies), Wdr82 (show WDR82 Antibodies), PP1 (show PPA1 Antibodies)) has a role in the regulation of chromatin structure during the transition from mitosis into interphase
PNUTS has a role in protein kinase A-regulated targeting of PP1 (show PPA1 Antibodies) to specific RNA-associated complexes in the nucleus
PNUTS, encoded by CAT 53 on 6p21.3, may have a role in the progression of AD.
results illustrate an involvement of the PNUTS:PP1 holoenzyme in chromosome decondensation in vitro and argue that PNUTS functions as a PP1 (show PPA1 Antibodies)-targeting subunit in this process
Findings suggest that PNUTS may play an important role in controlling cell death in response to cellular stresses such as hypoxia through the post-translational modification of p53 (show TP53 Antibodies) and MDM2 (show MDM2 Antibodies).
stimulation of PP1 (show PPP1CC Antibodies) activity via siRNA mediated knockdown of its interacting protein PNUTS (Phosphatase Nuclear Targeting Subunit) leads to Rb dephosphorylation and apoptosis in cancer cells
Protein phosphatase 1 (show PPP1CB Antibodies) (PP1 (show PPP1CC Antibodies)) and GABA(C (show GABRR1 Antibodies)) receptors simultaneously bind to different domains of PNUTS, demonstrating that PNUTS crosslinks PP1 (show PPP1CC Antibodies) and GABA(C (show GABRR1 Antibodies)) receptors.
This gene encodes a protein phosphatase 1 binding protein. The encoded protein plays a role in many cellular processes including cell cycle progression, DNA repair and apoptosis by regulating the activity of protein phosphatase 1. This gene lies within the major histocompatibility complex class I region on chromosome 6, and alternatively spliced transcript variants have been observed for this gene.
HLA-C associated transcript 53
, MHC class I region proline-rich protein CAT53
, PP1-binding protein of 114 kDa
, phosphatase 1 nuclear targeting subunit
, protein phosphatase 1, regulatory (inhibitor) subunit 10
, serine/threonine-protein phosphatase 1 regulatory subunit 10
, HLA-C adjacent transcript 53
, protein phosphatase I
, putative protein phosphatase 1 nuclear targeting subunit