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PPP1R9A is imprinted, and located in a cluster of imprinted genes on chromosome 7q12. Additionally we are shipping PPP1R9A Antibodies (58) and and many more products for this protein.
two homologs neurabin and spinophilin (show PPP1R9B ELISA Kits) play important yet distinct roles in the regulation of anxiety- and depression-like behaviors in an age-dependent manner.
Data indicate that In arrestin 3 (show ARRB2 ELISA Kits) deficient mice, where the alpha2B (show ADRA2B ELISA Kits) adrenergic receptor has a stronger binding to spinophilin (show PPP1R9B ELISA Kits), the hypertensive response is enhanced.
Ppp1r9a gene, found in a cluster of imprinted genes on chromosome 6, is preferentially expressed from the maternal allele at embryonic stages, but biallelically expressed in neonatal tissues.
The spinophilin (show PPP1R9B ELISA Kits) interactome was charaterized in subcellular fractions solubilized from adult rodent striatum.
there is a novel PP1gamma1-selective interaction domain in neurabin that may allow for selective regulation and/or subcellular targeting of PP1 (show PPP1CC ELISA Kits) isoforms
Neurabin I mediates Rac3-induced neuritogenesis, possibly by anchoring Rac3 to growth cone F-actin.
These data establish a requirement for synaptic scaffolding in dopamine-mediated responses, and further indicate that spinophilin (show PPP1R9B ELISA Kits) and neurabin play distinct roles in dopaminergic signal transduction and psychostimulant response.
results indicate that neurabin regulates contextual fear memory and LTP (show SCP2 ELISA Kits) in hippocampal CA1 (show CA1 ELISA Kits) pyramidal neurons
MARCKS (show MARCKS ELISA Kits) and PPP1R9A might contribute to spine loss in schizophrenia and bipolar disorder through their interactions.
CHN2 (show CHN2 ELISA Kits), ABCB1 (show ABCB1 ELISA Kits) and PPP1R9A expression on chromosome 7 is implicated in the pathogenesis of hepatosplenic T-cell lymphoma distinguishing it from other malignancies.
Studies suggest that any change in substrate specificity of the spinophilin (show PPP1R9B ELISA Kits) : PP1 (show PPA1 ELISA Kits) holoenzyme complex was probably due to direct modification of a PP1 (show PPA1 ELISA Kits) substrate binding surface.
PPP1R9A gene is imprinted, with preferential expression from the maternal allele in embryonic skeletal muscle and extra-embryonic tissues, but biallelic expression in other embryonic tissues.
This gene is imprinted, and located in a cluster of imprinted genes on chromosome 7q12. This gene is transcribed in both neuronal and multiple embryonic tissues, and it is maternally expressed mainly in embryonic skeletal muscle tissues and biallelically expressed in other embryonic tissues. The protein encoded by this gene includes a PDZ domain and a sterile alpha motif (SAM). It is a regulatory subunit of protein phosphatase I, and controls actin cytoskeleton reorganization. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
, neural tissue-specific F-actin binding protein
, neural tissue-specific F-actin-binding protein I
, protein phosphatase 1, regulatory (inhibitor) subunit 9A
, actin-binding protein neurabin
, neurabin 1
, protein phosphatase 1 regulatory subunit 9A