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IASPP is one of the most evolutionarily conserved inhibitors of p53 (TP53; MIM 191170), whereas ASPP1 (MIM 606455) and ASPP2 (MIM 602143) are activators of p53.. Additionally we are shipping Protein Phosphatase 1, Regulatory Subunit 13 Like Proteins (4) and Protein Phosphatase 1, Regulatory Subunit 13 Like Kits (2) and many more products for this protein.
Showing 10 out of 64 products:
Dog (Canine) Polyclonal PPP1R13L Primary Antibody for EIA, IHC (p) - ABIN401339
Laska, Nexø, Vistisen, Poulsen, Loft, Vogel: Polymorphisms in RAI and in genes of nucleotide and base excision repair are not associated with risk of testicular cancer. in Cancer letters 2005
Show all 6 references for ABIN401339
Cow (Bovine) Polyclonal PPP1R13L Primary Antibody for WB - ABIN2780798
Tomoda, Takahashi, Hibi, Asamitsu, Ishida, Kondo, Fujii, Okamoto: Molecular docking analysis of the protein-protein interaction between RelA-associated inhibitor and tumor suppressor protein p53 and its inhibitory effect on p53 action. in Cancer science 2008
Dog (Canine) Polyclonal PPP1R13L Primary Antibody for EIA, WB - ABIN318866
Zhang, Diao, Rao, Xing, Liu, Liao, Wang, Wang: Identification of a novel isoform of iASPP and its interaction with p53. in Journal of molecular biology 2007
iASPP expression may act as a predictive marker of prostate cancer progression.
These data demonstrate that by interacting with desmoplakin (show DSP Antibodies) and desmin (show DES Antibodies), iASPP is an important regulator of desmosomal function both in vitro and in vivo.
p53 (show TP53 Antibodies)-mediated neuronal cell death after stroke can be nontranscriptionally regulated by a novel mechanism involving suppression of endogenous cell death inhibitors by miR (show MLXIP Antibodies)-124.
PPP1R13L has an essential role in embryonic eyelid closure as well in development of meibomian glands and the anterior segment of the eye
These data showed iASPP to be a key regulator of epithelial homeostasis in skin.
Inhibitor of apoptosis-stimulating protein of p53 (iASPP) prevents senescence and is required for epithelial stratification.
Mice with mutation in Nkip1 (Ppp1r13l) represent a potentially important model for the analysis of the role of inflammatory processes in heart disease.
Studies revealed that overexpression of PPP1R13L causes faster p53 (show TP53 Antibodies) degradation, a likely explanation for the depletion of p53 (show TP53 Antibodies).
Our study provides the first evidence that high iASPP-SV expression may be a novel prognostic factor and therapeutic target for glioma
we were able to reproduce previously found associations between PPP1R13L and CD3EAP (show CD3EAP Antibodies) polymorphisms and lung cancer risk in an increased study group, and we found interactions between NFKB1 (show NFKB1 Antibodies) rs28362491-PPP1R13L rs1970764 and smoking duration and between CD3EAP (show CD3EAP Antibodies) rs735482 and smoking duration
inhibitor of apoptosis-stimulating protein of p53 (iASPP) was identified to be a direct target of miR (show MLXIP Antibodies)-140 in pancreatic duct adenocarcinoma specimens and cell lines
we show that iASPP is a novel substrate of caspases in response to apoptotic stimuli
one novel region within PPP1R13L is hypomethylated in all transient neonatal diabetes type 1 patients included in this study
destabilization of p300/CBP (show CREBBP Antibodies) by downregulation of iASPP expression levels appears to represent a molecular mechanism that contributes to chemoresistance in melanoma cells.
One of the proteins identified, iASPP, showed reduced levels in the presence of GSK-3 (show GSK3b Antibodies). Further, blocking iASPP activity increased cell death, particularly in p53 (show TP53 Antibodies) wild-type BC3 PEL cells.
The present study showed that iASPP is overexpressed in oral cavity squamous cell carcinomas (OSCC)tissues and increased cytoplasmic iASPP is correlated with recurrence and poor survival outcomes in OSCC patients
results suggest that NFKB1 (show NFKB1 Antibodies) common variants and smoking duration and smoking duration-PPP1R13L rs1970764 interaction could be concerned with the lung cancer development in a Chinese population
Frameshift mutation in PPP1R13L causes Cardiomyopathy and woolly haircoat syndrome in Poll Hereford cattle.
IASPP is one of the most evolutionarily conserved inhibitors of p53 (TP53\; MIM 191170), whereas ASPP1 (MIM 606455) and ASPP2 (MIM 602143) are activators of p53.
NFkB interacting protein 1
, NFkB-interacting protein 1
, PPP1R13B-like protein
, inhibitor of ASPP protein
, protein iASPP
, relA-associated inhibitor
, inhibitor of apoptosis stimulating protein of p53
, protein phosphatase 1, regulatory (inhibitor) subunit 13 like
, retinoic acid induced 4