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Protein Phosphatase 1, Regulatory Subunit 13 Like Proteins (PPP1R13L)

IASPP is one of the most evolutionarily conserved inhibitors of p53 (TP53\; MIM 191170), whereas ASPP1 (MIM 606455) and ASPP2 (MIM 602143) are activators of p53.[supplied by OMIM, Mar 2008].. Additionally we are shipping Protein Phosphatase 1, Regulatory Subunit 13 Like Antibodies (58) and Protein Phosphatase 1, Regulatory Subunit 13 Like Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PPP1R13L 333654 Q5I1X5
PPP1R13L 10848 Q8WUF5
Rat PPP1R13L PPP1R13L 686781  
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Top Protein Phosphatase 1, Regulatory Subunit 13 Like Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

PPP1R13L Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L) Interaction Partners

Mouse (Murine) Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L) interaction partners

  1. iASPP expression may act as a predictive marker of prostate cancer progression.

  2. These data demonstrate that by interacting with desmoplakin and desmin (show DES Proteins), iASPP is an important regulator of desmosomal function both in vitro and in vivo.

  3. p53 (show TP53 Proteins)-mediated neuronal cell death after stroke can be nontranscriptionally regulated by a novel mechanism involving suppression of endogenous cell death inhibitors by miR (show MLXIP Proteins)-124.

  4. PPP1R13L has an essential role in embryonic eyelid closure as well in development of meibomian glands and the anterior segment of the eye

  5. These data showed iASPP to be a key regulator of epithelial homeostasis in skin.

  6. Inhibitor of apoptosis-stimulating protein of p53 (iASPP) prevents senescence and is required for epithelial stratification.

  7. Mice with mutation in Nkip1 (Ppp1r13l) represent a potentially important model for the analysis of the role of inflammatory processes in heart disease.

  8. Studies revealed that overexpression of PPP1R13L causes faster p53 (show TP53 Proteins) degradation, a likely explanation for the depletion of p53 (show TP53 Proteins).

Human Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L) interaction partners

  1. we show that iASPP is a novel substrate of caspases in response to apoptotic stimuli

  2. one novel region within PPP1R13L is hypomethylated in all transient neonatal diabetes type 1 patients included in this study

  3. destabilization of p300/CBP (show CREBBP Proteins) by downregulation of iASPP expression levels appears to represent a molecular mechanism that contributes to chemoresistance in melanoma cells.

  4. One of the proteins identified, iASPP, showed reduced levels in the presence of GSK-3. Further, blocking iASPP activity increased cell death, particularly in p53 (show TP53 Proteins) wild-type BC3 PEL cells.

  5. The present study showed that iASPP is overexpressed in oral cavity squamous cell carcinomas (OSCC)tissues and increased cytoplasmic iASPP is correlated with recurrence and poor survival outcomes in OSCC patients

  6. results suggest that NFKB1 (show NFKB1 Proteins) common variants and smoking duration and smoking duration-PPP1R13L rs1970764 interaction could be concerned with the lung cancer development in a Chinese population

  7. iASPP expression may act as a predictive marker of prostate cancer progression.

  8. data highlight the importance of 14-3-3 (show YWHAQ Proteins) proteins in antiviral responses and identify RelA-associated inhibitor and sirtuin 1 (show SIRT1 Proteins) as novel regulators of antiviral innate immune responses.

  9. These data demonstrate that by interacting with desmoplakin and desmin (show DES Proteins), iASPP is an important regulator of desmosomal function both in vitro and in vivo.

  10. Authors have identified a novel mechanism modulating autophagy in keratinocytes that relies upon iASPP expression specifically reducing the interaction of Atg5 (show ATG5 Proteins)-Atg12 (show ATG12 Proteins) with Atg16L1 (show ATG16L1 Proteins).

Cow (Bovine) Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L) interaction partners

  1. Frameshift mutation in PPP1R13L causes Cardiomyopathy and woolly haircoat syndrome in Poll Hereford cattle.

Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L) Protein Profile

Protein Summary

IASPP is one of the most evolutionarily conserved inhibitors of p53 (TP53\; MIM 191170), whereas ASPP1 (MIM 606455) and ASPP2 (MIM 602143) are activators of p53.

Gene names and symbols associated with PPP1R13L

  • protein phosphatase 1, regulatory (inhibitor) subunit 13 like (Ppp1r13l)
  • protein phosphatase 1, regulatory (inhibitor) subunit 13 like (ppp1r13l)
  • protein phosphatase 1, regulatory subunit 13 like (PPP1R13L)
  • protein phosphatase 1, regulatory subunit 13 like (ppp1r13l)
  • protein phosphatase 1, regulatory subunit 13 like (Ppp1r13l)
  • AV260376 protein
  • IASPP protein
  • NKIP1 protein
  • RAI protein
  • RAI4 protein
  • wa3 protein
  • zgc:113058 protein

Protein level used designations for PPP1R13L

NFkB interacting protein 1 , NFkB-interacting protein 1 , PPP1R13B-like protein , inhibitor of ASPP protein , protein iASPP , relA-associated inhibitor , inhibitor of apoptosis stimulating protein of p53 , protein phosphatase 1, regulatory (inhibitor) subunit 13 like , retinoic acid induced 4

GENE ID SPECIES
333654 Mus musculus
541507 Danio rerio
10848 Homo sapiens
612286 Canis lupus familiaris
505818 Bos taurus
447427 Xenopus laevis
686781 Rattus norvegicus
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