Protein Phosphatase 1, Regulatory Subunit 13 Like Proteins (PPP1R13L)

IASPP is one of the most evolutionarily conserved inhibitors of p53 (TP53\; MIM 191170), whereas ASPP1 (MIM 606455) and ASPP2 (MIM 602143) are activators of p53.[supplied by OMIM, Mar 2008].. Additionally we are shipping Protein Phosphatase 1, Regulatory Subunit 13 Like Antibodies (63) and Protein Phosphatase 1, Regulatory Subunit 13 Like Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PPP1R13L 333654 Q5I1X5
PPP1R13L 10848 Q8WUF5
Rat PPP1R13L PPP1R13L 686781  
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Top Protein Phosphatase 1, Regulatory Subunit 13 Like Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$11,073.30
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Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
$11,073.30
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HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
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PPP1R13L Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L) Interaction Partners

Mouse (Murine) Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L) interaction partners

  1. miR (show MLXIP Proteins)-182 plays an aggressive role in the cerebral ischemia injury, and this is associated with inhibited iASPP expression.

  2. iASPP expression may act as a predictive marker of prostate cancer progression.

  3. These data demonstrate that by interacting with desmoplakin and desmin (show DES Proteins), iASPP is an important regulator of desmosomal function both in vitro and in vivo.

  4. p53 (show TP53 Proteins)-mediated neuronal cell death after stroke can be nontranscriptionally regulated by a novel mechanism involving suppression of endogenous cell death inhibitors by miR (show MLXIP Proteins)-124.

  5. PPP1R13L has an essential role in embryonic eyelid closure as well in development of meibomian glands and the anterior segment of the eye

  6. These data showed iASPP to be a key regulator of epithelial homeostasis in skin.

  7. Inhibitor of apoptosis-stimulating protein of p53 (iASPP) prevents senescence and is required for epithelial stratification.

  8. Mice with mutation in Nkip1 (Ppp1r13l) represent a potentially important model for the analysis of the role of inflammatory processes in heart disease.

  9. Studies revealed that overexpression of PPP1R13L causes faster p53 (show TP53 Proteins) degradation, a likely explanation for the depletion of p53 (show TP53 Proteins).

Human Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L) interaction partners

  1. UCA1 might promote proliferation and migration of glioma, to regulate the tumor growth and metastasis via miR (show MLXIP Proteins)-182 dependent iASPP regulation.

  2. Results demonstrate that iASPP is overexpressed in bladder cancer and promotes the malignancy of bladder cancer

  3. lncRNA H19 (show NCKAP1 Proteins) interacts with miR (show MLXIP Proteins)-140 to modulate glioma growth by targeting iASPP

  4. Increased expression of p53 (show TP53 Proteins) and ASPP1 (show PPP1R13B Proteins) and downregulation of iASPP.

  5. Our study provides the first evidence that high iASPP-SV expression may be a novel prognostic factor and therapeutic target for glioma

  6. we were able to reproduce previously found associations between PPP1R13L and CD3EAP (show CD3EAP Proteins) polymorphisms and lung cancer risk in an increased study group, and we found interactions between NFKB1 (show NFKB1 Proteins) rs28362491-PPP1R13L rs1970764 and smoking duration and between CD3EAP (show CD3EAP Proteins) rs735482 and smoking duration

  7. inhibitor of apoptosis-stimulating protein of p53 (iASPP) was identified to be a direct target of miR (show MLXIP Proteins)-140 in pancreatic duct adenocarcinoma specimens and cell lines

  8. we show that iASPP is a novel substrate of caspases in response to apoptotic stimuli

  9. one novel region within PPP1R13L is hypomethylated in all transient neonatal diabetes type 1 patients included in this study

  10. destabilization of p300/CBP (show CREBBP Proteins) by downregulation of iASPP expression levels appears to represent a molecular mechanism that contributes to chemoresistance in melanoma cells.

Cow (Bovine) Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L) interaction partners

  1. Frameshift mutation in PPP1R13L causes Cardiomyopathy and woolly haircoat syndrome in Poll Hereford cattle.

Xenopus laevis Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L) interaction partners

  1. Data suggest Greatwall (show MASTL Proteins) kinase (Gwl (show MASTL Proteins)) associates with protein phosphatase 1 (show PPP1CB Proteins) (PP1 (show PPYR1 Proteins)), particularly PP1gamma subunit, which mediates dephosphorylation of Gwl (show MASTL Proteins) Ser (show SIGLEC1 Proteins)-883; consistent with mitotic activation of Gwl (show MASTL Proteins), its association with PP1 (show PPYR1 Proteins) is disrupted in mitotic cells; subunits PPP1R3B (show PPP1R3B Proteins) and PPP1R13L associate with Gwl (show MASTL Proteins); thus, PPP1R3B (show PPP1R3B Proteins) appears to act as cell cycle regulator in oocytes that functions by governing Gwl (show MASTL Proteins) dephosphorylation.

Protein Phosphatase 1, Regulatory Subunit 13 Like (PPP1R13L) Protein Profile

Protein Summary

IASPP is one of the most evolutionarily conserved inhibitors of p53 (TP53\; MIM 191170), whereas ASPP1 (MIM 606455) and ASPP2 (MIM 602143) are activators of p53.

Gene names and symbols associated with PPP1R13L

  • protein phosphatase 1, regulatory (inhibitor) subunit 13 like (Ppp1r13l)
  • protein phosphatase 1, regulatory (inhibitor) subunit 13 like (ppp1r13l)
  • protein phosphatase 1, regulatory subunit 13 like (PPP1R13L)
  • protein phosphatase 1, regulatory subunit 13 like (ppp1r13l)
  • protein phosphatase 1, regulatory subunit 13 like (Ppp1r13l)
  • AV260376 protein
  • IASPP protein
  • NKIP1 protein
  • RAI protein
  • RAI4 protein
  • wa3 protein
  • zgc:113058 protein

Protein level used designations for PPP1R13L

NFkB interacting protein 1 , NFkB-interacting protein 1 , PPP1R13B-like protein , inhibitor of ASPP protein , protein iASPP , relA-associated inhibitor , inhibitor of apoptosis stimulating protein of p53 , protein phosphatase 1, regulatory (inhibitor) subunit 13 like , retinoic acid induced 4

GENE ID SPECIES
333654 Mus musculus
541507 Danio rerio
10848 Homo sapiens
612286 Canis lupus familiaris
505818 Bos taurus
447427 Xenopus laevis
686781 Rattus norvegicus
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