Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
The protein encoded by PPP1R16B is membrane-associated and contains five ankyrin repeats, a protein phosphatase-1-interacting domain, and a carboxy-terminal CAAX box domain. Additionally we are shipping Protein Phosphatase 1, Regulatory Subunit 16B Antibodies (33) and Protein Phosphatase 1, Regulatory Subunit 16B Proteins (4) and many more products for this protein.
These data confirmed the barrier-protective role of TIMAP
phosphorylation of TIMAP on Ser331 by PKC represents a new mechanism of endothelial barrier regulation, through the inhibition of phospho-ERM dephosphorylation
Results indicate that PKC-phosphorylated ECE-1 (show ECE1 ELISA Kits) is a TIMAP-PP1c substrate and this phosphatase complex has an important role in endothelin-1 (show EDN1 ELISA Kits) production of EC through the regulation of ECE-1 (show ECE1 ELISA Kits) activity.
ROCK phosphorylated eEF1A1 (show EEF1A1 ELISA Kits) is a novel substrate for TIMAP-PP1 (show PPA1 ELISA Kits) underlining the complex regulatory role of TIMAP in the endothelium.
TIMAP promotes angiogenesis by suppressing PTEN-mediated Akt (show AKT1 ELISA Kits) inhibition in human glomerular endothelial cells.
Data suggest that double-thiophosphorylation of TIMAP has minor effect on its binding ability to PP1c, but considerably attenuates its inhibitory effect on the activity of PP1c.
TIMAP, a novel CAAX box protein regulated by TGF-beta1 (show TGFB1 ELISA Kits) and expressed in endothelial cells.
involvement of TIMAP in PKA-mediated moesin (show MSN ELISA Kits) dephosphorylation and the importance of this dephosphorylation in TIMAP-mediated endothelial cell barrier protection
TIMAP can modify protein phosphorylation independent of its function as a PP1c regulatory subunit, namely by masking phosphorylation sites of binding partners like PP1c and LAMR1 (show RPSA ELISA Kits).
TIMAP is a target for PKA-primed GSK-3beta (show GSK3b ELISA Kits)-mediated phosphorylation. This phosphorylation controls TIMAP association and activity of PP1c
The protein encoded by this gene is membrane-associated and contains five ankyrin repeats, a protein phosphatase-1-interacting domain, and a carboxy-terminal CAAX box domain. Synthesis of the encoded protein is inhibited by transforming growth factor beta-1. The protein may bind to the membrane through its CAAX box domain and may act as a signaling molecule through interaction with protein phosphatase-1. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
CAAX box protein TIMAP
, TGF-beta-inhibited membrane-associated protein
, protein phosphatase 1 regulatory inhibitor subunit 16B
, whn-dependent transcript 4
, ankyrin repeat domain protein 4
, ankyrin repeat domain-containing protein 4
, protein phosphatase 1, regulatory (inhibitor) subunit 16B