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anti-Protein Phosphatase 1, Regulatory Subunit 3A (PPP1R3A) Antibodies

The glycogen-associated form of protein phosphatase-1 (PP1) derived from skeletal muscle is a heterodimer composed of a 37-kD catalytic subunit and a 124-kD targeting and regulatory subunit. Additionally we are shipping Protein Phosphatase 1, Regulatory Subunit 3A Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PPP1R3A 140491 Q99MR9
PPP1R3A 5506 Q16821
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Top anti-Protein Phosphatase 1, Regulatory Subunit 3A Antibodies at antibodies-online.com

Showing 10 out of 33 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, FACS, WB Flow cytometric analysis of Jurkat cells using PPP1R3A Antibody  (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Western blot analysis of PPP1R3A Antibody  in Jurkat cell line lysates (35ug/lane). This demonstrates the PPP1R3A antibody detected the PPP1R3A protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from MCF-7/COLO cells, using PPP1R3A Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-PPP1R3A Antibody Titration: 0.2-1 ug/mlPositive Control: THP-1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, WB PPP1R3A Antibody (Center) (ABIN654633) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit APC FACS, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL Log in to see 14 Days
$201.19
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details

PPP1R3A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


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Top referenced anti-Protein Phosphatase 1, Regulatory Subunit 3A Antibodies

  1. Human Polyclonal PPP1R3A Primary Antibody for EIA, FACS - ABIN954272 : Yoshida, Kato, Yokoi, Oguri, Watanabe, Metoki, Yoshida, Satoh, Aoyagi, Nishigaki, Nozawa, Yamada: Association of genetic variants with chronic kidney disease in individuals with different lipid profiles. in International journal of molecular medicine 2009 (PubMed)
    Show all 2 references for ABIN954272

  2. Human Polyclonal PPP1R3A Primary Antibody for ELISA, WB - ABIN1535222 : Xia, Scherer, Cohen, Majer, Xi, Norman, Knowler, Bogardus, Prochazka: A common variant in PPP1R3 associated with insulin resistance and type 2 diabetes. in Diabetes 1998 (PubMed)
    Show all 2 references for ABIN1535222

More Antibodies against Protein Phosphatase 1, Regulatory Subunit 3A Interaction Partners

Mouse (Murine) Protein Phosphatase 1, Regulatory Subunit 3A (PPP1R3A) interaction partners

  1. results show that dysfunction of subunit PPP1R3A of protein phosphatase 1 (show PPP1CB Antibodies) leads to weight gain, increased fat deposition and insulin (show INS Antibodies) resistance

  2. Mice in which human PPP1R3A C1984DeltaAG replaced mouse PP1R3A had decreased muscle glycogen leve (show GYS1 Antibodies)ls because failure of the trunc (show GYS1 Antibodies)ated mutant to bind glycogen & colocalize with glycogen synthase (GS) decreased GS & increased glycogen phosphorylase activity.

  3. Backcrossing of G(M)-/- mice onto two different genetic backgrounds gave rise to lean, glucose-tolerant, insulin (show INS Antibodies)-sensitive G(M)-/- mice indicating that at least one variant gene,is required for the development of the prediabetic phenotype of obese mice.

  4. Disruption of the Ppp1r3a gene does not result in either fat deposition or insulin (show INS Antibodies) resistance, but PPP1r3a is essential for control of glycogen (show GYS1 Antibodies) metabolism by exercise.

Human Protein Phosphatase 1, Regulatory Subunit 3A (PPP1R3A) interaction partners

  1. results demonstrate that hScrib (show SCRIB Antibodies) acts as a scaffold to integrate the control of the PP1gamma and ERK (show EPHB2 Antibodies) signaling pathways and explains how disruption of hScrib (show SCRIB Antibodies) localisation can contribute towards the development of human malignancy

  2. A joint effect between the Asp905 and BMI increases the risk of type 2 diabetes, and Asp905Tyr and ARE polymorphism of PPP1R3 gene are not the major diabetogenic gene variants in Chinese population.

  3. We describe a family in which five individuals with severe insulin (show INS Antibodies) resistance, but no unaffected family members, were compound heterozygous with respect to frameshift/premature stop mutations in two unlinked genes, PPARG (show PPARG Antibodies) and PPP1R3A

  4. G(M) promotes glycogen (show GYS1 Antibodies) storage and inversely regulates glycogen synthase and glycogen (show GYS1 Antibodies) phosphorylase activities, while, specifically, synthase phosphatase activity of G(M)-PP1 (show PPA1 Antibodies) is inhibited by glycogen (show GYS1 Antibodies).

  5. Among the largest cohort of nondiabetic subjects (Caucasian, n = 112), the presence of the deletion allele (ARE-2) was associated with insulin (show INS Antibodies) resistance and hyperandrogenemia.

  6. Inactivation of PPP1R3 gene is associated with tumor progression and metastasis of colorectal cancers

  7. PPP1R3A C1984DeltaAG (stop codon 668) isthe 1st prevalent mutation that directly impairs glycogen (show GYS1 Antibodies) synthesis & decreases glycogen (show GYS1 Antibodies) levels in human skeletal muscle. It is present in approximately 1 in 70 UK whites.

Protein Phosphatase 1, Regulatory Subunit 3A (PPP1R3A) Antigen Profile

Protein Summary

The glycogen-associated form of protein phosphatase-1 (PP1) derived from skeletal muscle is a heterodimer composed of a 37-kD catalytic subunit and a 124-kD targeting and regulatory subunit. This gene encodes the regulatory subunit which binds to muscle glycogen with high affinity, thereby enhancing dephosphorylation of glycogen-bound substrates for PP1 such as glycogen synthase and glycogen phosphorylase kinase.

Gene names and symbols associated with PPP1R3A

  • protein phosphatase 1, regulatory (inhibitor) subunit 3A (Ppp1r3a) antibody
  • protein phosphatase 1, regulatory subunit 3A (PPP1R3A) antibody
  • protein phosphatase regulatory subunit (RG1) antibody
  • GM antibody
  • PP1G antibody
  • PPP1R3 antibody
  • PPP1R3A antibody
  • RG1 antibody
  • RGL antibody

Protein level used designations for PPP1R3A

protein phosphatase 1 glycogen-associated regulatory subunit , protein phosphatase 1 regulatory subunit 3A , protein phosphatase type-1 glycogen targeting subunit , RG1 , glycogen and sarcoplasmic reticulum binding subunit, skeletal muscle , glycogen-associated regulatory subunit of protein phosphatase-1 , protein phosphatase 1 glycogen- associated regulatory subunit , protein phosphatase 1 regulatory subunit GM , protein phosphatase 1, regulatory (inhibitor) subunit 3A , serine /threonine specific protein phosphatase , type-1 protein phosphatase skeletal muscle glycogen targeting subunit

GENE ID SPECIES
140491 Mus musculus
5506 Homo sapiens
100009140 Oryctolagus cuniculus
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