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Protein Phosphatase 1, Regulatory Subunit 3A Proteins (PPP1R3A)

The glycogen-associated form of protein phosphatase-1 (PP1) derived from skeletal muscle is a heterodimer composed of a 37-kD catalytic subunit and a 124-kD targeting and regulatory subunit. Additionally we are shipping Protein Phosphatase 1, Regulatory Subunit 3A Antibodies (32) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PPP1R3A 140491 Q99MR9
PPP1R3A 5506 Q16821
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Top Protein Phosphatase 1, Regulatory Subunit 3A Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 69 to 74 Days
$9,050.32
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 69 to 74 Days
$12,906.52
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HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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PPP1R3A Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Protein Phosphatase 1, Regulatory Subunit 3A (PPP1R3A) Interaction Partners

Mouse (Murine) Protein Phosphatase 1, Regulatory Subunit 3A (PPP1R3A) interaction partners

  1. results show that dysfunction of subunit PPP1R3A of protein phosphatase 1 (show PPP1CB Proteins) leads to weight gain, increased fat deposition and insulin (show INS Proteins) resistance

  2. Mice in which human PPP1R3A C1984DeltaAG replaced mouse PP1R3A had decreased muscle glycogen leve (show GYS1 Proteins)ls because failure of the trunc (show GYS1 Proteins)ated mutant to bind glycogen & colocalize with glycogen synthase (GS) decreased GS & increased glycogen phosphorylase activity.

  3. Backcrossing of G(M)-/- mice onto two different genetic backgrounds gave rise to lean, glucose-tolerant, insulin (show INS Proteins)-sensitive G(M)-/- mice indicating that at least one variant gene,is required for the development of the prediabetic phenotype of obese mice.

  4. Disruption of the Ppp1r3a gene does not result in either fat deposition or insulin (show INS Proteins) resistance, but PPP1r3a is essential for control of glycogen (show GYS1 Proteins) metabolism by exercise.

Human Protein Phosphatase 1, Regulatory Subunit 3A (PPP1R3A) interaction partners

  1. results demonstrate that hScrib acts as a scaffold to integrate the control of the PP1gamma and ERK signaling pathways and explains how disruption of hScrib localisation can contribute towards the development of human malignancy

  2. A joint effect between the Asp905 and BMI increases the risk of type 2 diabetes, and Asp905Tyr and ARE polymorphism of PPP1R3 gene are not the major diabetogenic gene variants in Chinese population.

  3. We describe a family in which five individuals with severe insulin (show INS Proteins) resistance, but no unaffected family members, were compound heterozygous with respect to frameshift/premature stop mutations in two unlinked genes, PPARG (show PPARG Proteins) and PPP1R3A

  4. G(M) promotes glycogen (show GYS1 Proteins) storage and inversely regulates glycogen synthase and glycogen (show GYS1 Proteins) phosphorylase activities, while, specifically, synthase phosphatase activity of G(M)-PP1 (show PPA1 Proteins) is inhibited by glycogen (show GYS1 Proteins).

  5. Among the largest cohort of nondiabetic subjects (Caucasian, n = 112), the presence of the deletion allele (ARE-2) was associated with insulin (show INS Proteins) resistance and hyperandrogenemia.

  6. Inactivation of PPP1R3 gene is associated with tumor progression and metastasis of colorectal cancers

  7. PPP1R3A C1984DeltaAG (stop codon 668) isthe 1st prevalent mutation that directly impairs glycogen (show GYS1 Proteins) synthesis & decreases glycogen (show GYS1 Proteins) levels in human skeletal muscle. It is present in approximately 1 in 70 UK whites.

Protein Phosphatase 1, Regulatory Subunit 3A (PPP1R3A) Protein Profile

Protein Summary

The glycogen-associated form of protein phosphatase-1 (PP1) derived from skeletal muscle is a heterodimer composed of a 37-kD catalytic subunit and a 124-kD targeting and regulatory subunit. This gene encodes the regulatory subunit which binds to muscle glycogen with high affinity, thereby enhancing dephosphorylation of glycogen-bound substrates for PP1 such as glycogen synthase and glycogen phosphorylase kinase.

Gene names and symbols associated with PPP1R3A

  • protein phosphatase 1, regulatory (inhibitor) subunit 3A (Ppp1r3a)
  • protein phosphatase 1, regulatory subunit 3A (PPP1R3A)
  • protein phosphatase regulatory subunit (RG1)
  • GM protein
  • PP1G protein
  • PPP1R3 protein
  • PPP1R3A protein
  • RG1 protein
  • RGL protein

Protein level used designations for PPP1R3A

protein phosphatase 1 glycogen-associated regulatory subunit , protein phosphatase 1 regulatory subunit 3A , protein phosphatase type-1 glycogen targeting subunit , RG1 , glycogen and sarcoplasmic reticulum binding subunit, skeletal muscle , glycogen-associated regulatory subunit of protein phosphatase-1 , protein phosphatase 1 glycogen- associated regulatory subunit , protein phosphatase 1 regulatory subunit GM , protein phosphatase 1, regulatory (inhibitor) subunit 3A , serine /threonine specific protein phosphatase , type-1 protein phosphatase skeletal muscle glycogen targeting subunit

GENE ID SPECIES
140491 Mus musculus
5506 Homo sapiens
100009140 Oryctolagus cuniculus
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