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Protein Phosphatase 1, Regulatory Subunit 3C (PPP1R3C) ELISA Kits

PPP1R3C encodes a regulatory subunit of protein phosphatase-1 (PP1). Additionally we are shipping PPP1R3C Antibodies (26) and PPP1R3C Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse PPP1R3C PPP1R3C 53412 Q7TMB3
Anti-Human PPP1R3C PPP1R3C 5507 Q9UQK1
Anti-Rat PPP1R3C PPP1R3C 309513 Q5U2R5
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More ELISA Kits for PPP1R3C Interaction Partners

Mouse (Murine) Protein Phosphatase 1, Regulatory Subunit 3C (PPP1R3C) interaction partners

  1. metabolic crosstalk is due to decreased mTORC1 and SREBP activity in PTG (show LPCAT3 ELISA Kits) knockout mice or knockdown cells, suggesting a positive feedback loop in which once accumulated, glycogen (show GYS1 ELISA Kits) stimulates the mTORC1/SREBP1 (show SREBF1 ELISA Kits) pathway to shift energy storage to lipogenesis.

  2. removing PTG (show LPCAT3 ELISA Kits), a glycogen (show GYS1 ELISA Kits) synthesis activator protein, nearly completely eliminates Lafora bodies and rescues the neurodegeneration, myoclonus,seizure susceptibility, and behavioral abnormality.

  3. Laforin (show EPM2A ELISA Kits)-deficient mice lacking PTG (show LPCAT3 ELISA Kits) have greatly decreased Lafora bodies and normal glycogen (show GYS1 ELISA Kits) levels.

  4. These data suggest that PTG (show LPCAT3 ELISA Kits) plays a critical role in glycogen (show GYS1 ELISA Kits) synthesis and is necessary to maintain the appropriate metabolic balance for the partitioning of fuel substrates between glycogen (show GYS1 ELISA Kits) and lipid.

  5. PTG (show LPCAT3 ELISA Kits) overexpression in 3T3-L1 adipocytes discretely stimulates PP1 (show PPP1CC ELISA Kits) activity against glycogen synthase and phosphorylase, resulting in a marked and specific increase in glucose uptake and storage as glycogen (show GYS1 ELISA Kits).

  6. These data indicate that disruption of PTG (show LPCAT3 ELISA Kits) expression resulted in the uncoupling of PP1 (show PPP1CC ELISA Kits) activity from glycogen (show GYS1 ELISA Kits) metabolizing enzymes, the enhancement of glycogenolysis, and a dramatic decrease in cellular glycogen (show GYS1 ELISA Kits) levels.

  7. mouse protein targeting to glycogen (PTG) promoter is regulated by the FoxA2 (show FOXA2 ELISA Kits) forkhead protein (show FOXO4 ELISA Kits) and by 3',5'-cyclic adenosine 5'-monophosphate in H4IIE hepatoma cells

Human Protein Phosphatase 1, Regulatory Subunit 3C (PPP1R3C) interaction partners

  1. PPP1R3C, a novel hypermethylated gene in colorectal cancer, may play a critical role in cancer cell growth in association with glucose levels.

  2. detection of methylation of PPP1R3C alone or in combination with EFHD1 (show EFHD1 ELISA Kits) in plasma DNA showed high sensitivity and specificity in CRC (show CALR ELISA Kits) detection, and may be useful detection method for CRC (show CALR ELISA Kits), especially for early-stage CRCs.

  3. Findings suggest that variations in PTG may condition the course of Lafora disease and establish PTG as a potential target for pharmacogenetic and therapeutic approaches.

  4. Results demonstrated that HIF1 (show HIF1A ELISA Kits) promotes glycogen (show GYS1 ELISA Kits) accumulation through regulating PPP1R3C expression under hypoxia, which revealed a novel metabolic adaptation of cells to hypoxia.

  5. phosphorylation of R5/PTG at Ser (show SIGLEC1 ELISA Kits)-8 by AMPK (show PRKAA1 ELISA Kits) accelerates its laforin (show EPM2A ELISA Kits)/malin (show NHLRC1 ELISA Kits)-dependent ubiquitination and subsequent proteasomal degradation, which results in a decrease of its glycogenic activity.

PPP1R3C Antigen Profile

Antigen Summary

This gene encodes a regulatory subunit of protein phosphatase-1 (PP1). PP1 catalyzes reversible protein phosphorylation, which is important in a wide range of cellular activities: neuronal, muscular, RNA splicing, protein synthesis, cell death, and glycogen metabolism, to name just a few. By interacting with different regulatory subunits, PP1 is directed to different parts of the cell, to different substrates, or to respond to extracellular signals.

Gene names and symbols associated with PPP1R3C

  • protein phosphatase 1, regulatory (inhibitor) subunit 3C (Ppp1r3c) antibody
  • protein phosphatase 1, regulatory subunit 3C (PPP1R3C) antibody
  • protein phosphatase 1, regulatory subunit 3C (Ppp1r3c) antibody
  • PPP1R5 antibody
  • PTG antibody
  • R5 antibody

Protein level used designations for PPP1R3C

PP1 subunit R5 , protein phosphatase 1 binding protein PTG , protein phosphatase 1 regulatory subunit 3C , protein phosphatase 1 regulatory subunit 5 , protein phosphatase 1, regulatory (inhibitor) subunit 5 , protein targeting to glicogen , protein targeting to glycogen , PTG , Phosphatase 1, regulatory inhibitor subunit 5 , protein phosphatase 1, regulatory (inhibitor) subunit 3C , R5

GENE ID SPECIES
53412 Mus musculus
5507 Homo sapiens
309513 Rattus norvegicus
539466 Bos taurus
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