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anti-Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8) Antibodies

PPP1R8, through alternative splicing, encodes three different isoforms. Additionally we are shipping Protein Phosphatase 1, Regulatory Subunit 8 Proteins (9) and Protein Phosphatase 1, Regulatory Subunit 8 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PPP1R8 8260 P41227
PPP1R8 100336 Q8R3G1
PPP1R8 313030  
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Top anti-Protein Phosphatase 1, Regulatory Subunit 8 Antibodies at antibodies-online.com

Showing 10 out of 96 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PPP1R8 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: 293T cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN185050 staining (2µg/ml) of H460 lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-PPP1R8  Antibody Titration: 2.5 µg/mL ELISA Titer: 1:.12500  Positive Control: Human Thymus 100 μL Log in to see 2 to 3 Days
$229.00
Details
Cow Goat Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-PPP1R8 Antibody Titration: 1.25ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate WB Suggested Anti-PPP1R8  Antibody Titration: 1.25 µg/mL ELISA Titer: 1:312500  Positive Control: HepG2 cell lysate  PPP1R8 is supported by BioGPS gene expression data to be expressed in HepG2 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to ARD1A on HeLa cell (antibody concentration 10 µg/mL). ARD1 monoclonal antibody (M01), clone 4B7-H4 Western Blot analysis of ARD1 expression in Hela NE. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-PPP1R8 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: OVCAR-3 cell lysate WB Suggested Anti-PPP1R8  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: OVCAR-3 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), ELISA Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated IHC, WB 100 μg Log in to see 8 to 10 Days
$493.17
Details

PPP1R8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Protein Phosphatase 1, Regulatory Subunit 8 Antibodies

  1. Human Monoclonal PPP1R8 Primary Antibody for IF, WB - ABIN393761 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for ABIN393761

  2. Cow (Bovine) Polyclonal PPP1R8 Primary Antibody for WB - ABIN2778805 : Kumeta, Ogura, Adachi, Fujioka, Tanuma, Tanuma, Kikuchi, Inagaki: The NMR structure of the NIPP1 FHA domain. in Journal of biomolecular NMR 2008 (PubMed)

  3. Cow (Bovine) Polyclonal PPP1R8 Primary Antibody for EIA, IHC (p) - ABIN374344 : Nuytten, Beke, Van Eynde, Ceulemans, Beullens, Van Hummelen, Fuks, Bollen: The transcriptional repressor NIPP1 is an essential player in EZH2-mediated gene silencing. in Oncogene 2008 (PubMed)

  4. Chicken Polyclonal PPP1R8 Primary Antibody for WB - ABIN2779048 : Lesage, Beullens, Nuytten, Van Eynde, Keppens, Himpens, Bollen: Interactor-mediated nuclear translocation and retention of protein phosphatase-1. in The Journal of biological chemistry 2004 (PubMed)

  5. Human Polyclonal PPP1R8 Primary Antibody for IHC, ELISA - ABIN185050 : Beullens, Bollen: The protein phosphatase-1 regulator NIPP1 is also a splicing factor involved in a late step of spliceosome assembly. in The Journal of biological chemistry 2002 (PubMed)

More Antibodies against Protein Phosphatase 1, Regulatory Subunit 8 Interaction Partners

Human Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8) interaction partners

  1. Human Naa15 (NATH (show NAA15 Antibodies)) and Naa10 (ARD1 (show ARD1A Antibodies)) form a stable NatA complex which associates with ribosomes and performs co-translational N-terminal acetylation; Naa15 (NATH (show NAA15 Antibodies)) and Naa10 (ARD1 (show ARD1A Antibodies)) are cleaved during apoptosis resulting in decreased acetyltransferase activity

  2. The clinical spectrum of NAA10 (show ARD1A Antibodies).

  3. there is no difference in lysine acetylation of substrate proteins with or without Naa10 (show ARD1A Antibodies), suggesting that the substrates may be acetylated chemically rather than enzymatically.

  4. Combined high expression of Naa10p, SNCG (show SNCG Antibodies) and PRL-3 are associated with lymph node metastasis in breast cancer.

  5. De novo missense mutations in the NAA10 (show ARD1A Antibodies) gene cause severe non-syndromic developmental delay in males and females

  6. human ARD1 (show TRIM23 Antibodies) variants have different effects on cell proliferation, which may result from distinct subcellular localizations and autoacetylation activities.

  7. Naa10 (show ARD1A Antibodies) structure and function. [Review]

  8. Autoacetylation of ARD1 (show TRIM23 Antibodies) variants differentially regulates angiogenesis and cell proliferation in an isoform-specific manner.

  9. Data suggest overexpression of NIPP1 in HeLa cells causes induction of genes of mesenchymal lineage with reduction in cell proliferation; thus, key dephosphorylation events may be involved in epithelial-mesenchymal transition or transdifferentiation.

  10. ARD1 (show TRIM23 Antibodies) has a crucial role in the cellular response to oxidative stress as a bona fide regulator of MSRA (show MSRA Antibodies).

Mouse (Murine) Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8) interaction partners

  1. activation of the RAGE (show AGER Antibodies) by advanced glycation end products or other ligands suppresses NIPP1 expression in diabetic nephropathy, contributes to podocyte hypertrophy, and glomerular inflammation

  2. NIPP1(-/-) embryos showed severely retarded growth at embryonic day 6.5 (E6.5) and were resorbed by E8.5. This early embryonic lethality was not associated with increased apoptosis but correlated with impaired cell proliferation.

  3. NIPP1 has a role in the nuclear targeting and/or retention of PP1 (show PPP1CC Antibodies)

  4. Required for the global trimethylation of Histone 3 at Lysine 27 and is implicated in gene silencing by enhancer of zeste homolog (EZH)2 (show EZH2 Antibodies).

Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8) Antigen Profile

Protein Summary

This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.

Gene names and symbols associated with PPP1R8

  • N(alpha)-acetyltransferase 10, NatA catalytic subunit (NAA10) antibody
  • protein phosphatase 1, regulatory (inhibitor) subunit 8 (Ppp1r8) antibody
  • protein phosphatase 1, regulatory subunit 8 (PPP1R8) antibody
  • protein phosphatase 1, regulatory subunit 8 (ppp1r8) antibody
  • protein phosphatase 1, regulatory subunit 8 (Ppp1r8) antibody
  • zgc:63827 (zgc:63827) antibody
  • 6330548N22Rik antibody
  • ARD-1 antibody
  • ard1 antibody
  • ARD1A antibody
  • AU044684 antibody
  • DXS707 antibody
  • NATD antibody
  • NIPP-1 antibody
  • nipp1 antibody
  • PPP1R8 antibody
  • PRO2047 antibody
  • TE2 antibody

Protein level used designations for PPP1R8

ARD1 homolog A, N-acetyltransferase , N-acetyltransferase ARD1, human homolog of , N-alpha-acetyltransferase 10 , N-alpha-acetyltransferase 10, NatA catalytic subunit , N-terminal acetyltransferase complex ARD1 subunit homolog A , NIPP-1 , nuclear inhibitor of protein phosphatase 1 , protein phosphatase 1 regulatory inhibitor subunit 8 , protein phosphatase 1, regulatory (inhibitor) subunit 8 , protein phosphatase 1, regulatory inhibitor subunit 8 , RNase E , activator of RNA decay , nuclear inhibitor of protein phosphatase-1 alpha , nuclear subunit of PP-1 , protein phosphatase 1 regulatory subunit 8 , uncharacterized protein LOC799896

GENE ID SPECIES
8260 Homo sapiens
100336 Mus musculus
282319 Bos taurus
398974 Xenopus laevis
419564 Gallus gallus
5511 Homo sapiens
487340 Canis lupus familiaris
313030 Rattus norvegicus
799896 Danio rerio
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