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Protein Phosphatase 5, Catalytic Subunit Proteins (PPP5C)

PPP5C encodes a member of the Kunitz-type serine proteinase inhibitor family. Additionally we are shipping Protein Phosphatase 5, Catalytic Subunit Antibodies (120) and Protein Phosphatase 5, Catalytic Subunit Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PPP5C 5536 P53041
PPP5C 19060 Q60676
PPP5C 65179 P53042
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Top Protein Phosphatase 5, Catalytic Subunit Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rabbit His tag   1 mg Log in to see 56 to 66 Days
$1,994.67
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,411.83
Details

PPP5C Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

Top referenced Protein Phosphatase 5, Catalytic Subunit Proteins

  1. Human PPP5C Protein expressed in Wheat germ - ABIN1316089 : Horibe, Kohno, Haramoto, Ohara, Kawakami: Designed hybrid TPR peptide targeting Hsp90 as a novel anticancer agent. in Journal of translational medicine 2011 (PubMed)

More Proteins for Protein Phosphatase 5, Catalytic Subunit (PPP5C) Interaction Partners

Human Protein Phosphatase 5, Catalytic Subunit (PPP5C) interaction partners

  1. Data show that silencing tumor-endothelial cells (EC) for trypsinogen 4 (show PRSS3 Proteins) accumulated tissue factor pathway inhibitor-2 (TFPI-2 (show TFPI2 Proteins)) in the matrix.

  2. the importance of PP5 in CRC (show CALR Proteins) cell growth

  3. PPP5C could be essential for glioma cell growth.

  4. Hypermethylation of TFPI2 (show TFPI2 Proteins) promoter is increased in inflamed colon tissue.

  5. DNA methylation of TFPI2 may play an important role in the carcinogenesis of cervical cancer and that the differential methylation of TFPI2 may at least partially explain the disparity in cervical cancer incidence between Uygur and Han women.

  6. our findings suggested that the differential expression of MMP-2 (show MMP2 Proteins) and TFPI-2 (show TFPI2 Proteins) have a negative correlation in pancreatic carcinoma

  7. Measles Virus Infection Inactivates Cellular Protein Phosphatase 5 with Consequent Suppression of Sp1 (show PSG1 Proteins) and c-Myc (show MYC Proteins) Activities.

  8. Our finding suggests that the decreased expression of TFPI-2 (show TFPI2 Proteins) may play an important role in the carcinogenesis and progression, and may become a new adjunct marker in the diagnosis and prognosis in cholangiocarcinoma

  9. We demonstrate for the first time that PPP5C is essential for growth of HCC (show FAM126A Proteins) cells, which suggests that inhibition of PPP5C by RNAi may be a potential therapeutic strategy for the treatment of hepatocellular carcinoma.

  10. Data indicate that Cu-oxidized S100 calcium binding protein A4 (S100A4) interacted with S100 calcium binding protein A1 (S100A1) and prevented protein phosphatase 5 (PP5) activation.

Mouse (Murine) Protein Phosphatase 5, Catalytic Subunit (PPP5C) interaction partners

  1. Mice with inactivated protein phosphatase 5 have decreased adipogenesis.

  2. Ppp5c- knockout mice are resistant to weight gain induced by high fat diet.

  3. Chp-1 (show CHORDC1 Proteins) and melusin (show ITGB1BP2 Proteins) can interact with cochaperones PP5 and Sgt1 (show SUGT1 Proteins) and with each other in an ATP-dependent manner

  4. PP5 regulates the TGFbeta (show TGFB1 Proteins) pathway in MEFs by regulating the expression of SMAD3 (show SMAD3 Proteins) protein levels.

  5. Data show that protein phosphatase 5 (PP5), a nuclear receptor co-chaperone, reciprocally modulates the lipometabolic activities of GRalpha and PPARgamma.

  6. genetic disruption of PP5 is associated with enhanced and prolonged phosphorylation of a single serine (Ser (show SIGLEC1 Proteins)-345) on Chk1 (show CHEK1 Proteins)

  7. Constitutive over expression of serine/threonine protein phosphatase 5 augments estrogen-dependent tumor growth in mice

  8. tau is probably a physiological substrate of protein phosphatase 5 (PP5) and that the abnormal hyperphosphorylation of tau in Alzheimer disease might result in part from the decreased PP5 activity in the diseased brains

  9. Data suggest that endogenous protein phosphatase 5 can exert a negative modulatory effect on basal ACTH (show POMC Proteins) release in neurosecretion-competent AtT20 cells.

Protein Phosphatase 5, Catalytic Subunit (PPP5C) Protein Profile

Protein Summary

This gene encodes a member of the Kunitz-type serine proteinase inhibitor family. The protein can inhibit a variety of serine proteases including factor VIIa/tissue factor, factor Xa, plasmin, trypsin, chymotryspin and plasma kallikrein. This gene has been identified as a tumor suppressor gene in several types of cancer. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with PPP5C

  • protein phosphatase 5, catalytic subunit (ppp5c)
  • protein phosphatase 5, catalytic subunit (PPP5C)
  • protein phosphatase 5, catalytic subunit (Ppp5c)
  • tissue factor pathway inhibitor 2 (TFPI2)
  • AU020526 protein
  • fc83f08 protein
  • im:7146608 protein
  • MGC89961 protein
  • PP5 protein
  • PPP5 protein
  • PPP5C protein
  • PPT protein
  • REF1 protein
  • TFPI-2 protein
  • wu:fc83f08 protein
  • zgc:110801 protein

Protein level used designations for PPP5C

serine/threonine-protein phosphatase 5 , protein phosphatase 5, catalytic subunit , serine/threonine-protein phosphatase 5-like , PP-T , protein phosphatase T , ANP receptor , PPT , PP5 , placental protein 5 , retinal pigment epithelium cell factor 1

GENE ID SPECIES
398004 Xenopus laevis
456150 Pan troglodytes
493275 Xenopus (Silurana) tropicalis
510245 Bos taurus
541536 Danio rerio
592155 Strongylocentrotus purpuratus
612199 Canis lupus familiaris
716214 Macaca mulatta
100174541 Pongo abelii
100414496 Callithrix jacchus
100513542 Sus scrofa
100564151 Anolis carolinensis
100583672 Nomascus leucogenys
100186268 Ciona intestinalis
100208775 Hydra magnipapillata
100472775 Ailuropoda melanoleuca
5536 Homo sapiens
19060 Mus musculus
65179 Rattus norvegicus
7980 Homo sapiens
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