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The protein encoded by QKI is an RNA-binding protein that regulates pre-mRNA splicing, export of mRNAs from the nucleus, protein translation, and mRNA stability. Additionally we are shipping QKI Proteins (11) and many more products for this protein.
Showing 10 out of 91 products:
Human Polyclonal QKI Primary Antibody for EIA, IHC (p) - ABIN357831
Zhao, Tian, Xia, Macklin, Feng: Rescuing qkV dysmyelination by a single isoform of the selective RNA-binding protein QKI. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2006
Show all 3 references for ABIN357831
Human Polyclonal QKI Primary Antibody for IHC (p), WB - ABIN389155
Aberg, Saetre, Jareborg, Jazin: Human QKI, a potential regulator of mRNA expression of human oligodendrocyte-related genes involved in schizophrenia. in Proceedings of the National Academy of Sciences of the United States of America 2006
Show all 2 references for ABIN389155
Dog (Canine) Polyclonal QKI Primary Antibody for WB - ABIN374728
Wu, Reed, Grabowski, Artzt: Function of quaking in myelination: regulation of alternative splicing. in Proceedings of the National Academy of Sciences of the United States of America 2002
quaking is essential in maintaining endothelial barrier function.
QKI-7 recruits PAPD4 (show PAPD4 Antibodies) to regulate post-transcriptional polyadenylation of target mRNAs.
QKI has a role in posttranscriptionally guiding macrophage identity and function.
MYB (show MYB Antibodies)-QKI rearrangements promote tumorigenesis through three mechanisms: MYB (show MYB Antibodies) activation by truncation, enhancer translocation driving aberrant MYB (show MYB Antibodies)-QKI expression and hemizygous loss of the tumor suppressor QKI
Data implicate QKI in the pathophysiology of inflammation and leukemoogenesis where miR (show MLXIP Antibodies)-155 is involved.
miR (show MLXIP Antibodies)-155 regulates the cell cycle and invasion ability of colon cancer cells via the modulation of QKI expression
miR (show MLXIP Antibodies)-29a promotes scavenger receptor A expression by targeting QKI during monocyte-macrophage differentiation.
QKI is a novel Cancer stem cells (CSC) inhibitor and impaired multiple oral CSC properties via partial repression of SOX2 (show SOX2 Antibodies).
Using circScreen, study identified the RNA binding protein (show PTBP1 Antibodies) Quaking (QKI) as a major regulator of circRNA biogenesis in epithelial-mesenchymal transition (EMT (show ITK Antibodies)) and show that introduction of consensus binding sequences for QKI into the flanking introns is sufficient to cause circRNAs to be produced from exons that normally only undergo canonical linear splicing.
QKI as a key regulator of alternative splicing in lung cancer.
Complementary DNA (cDNA) for bovine quaking gene (Bqk), equine quaking gene (Eqk) and porcine quaking gene (Pqk), which are homologous to mouse quaking gene (qkI), were isolated, and their nucleotide sequences were determined.
miR (show MYLIP Antibodies)-499 was negatively correlated to the expression of QKI in testicular tissue.
findings reveal a crucial role for the miR (show MLXIP Antibodies)-214-Qki pathway in the regulation of neuronal dendritic development.
we identify QKI as the long-sought regulator of Neurofascin (show NFASC Antibodies) alternative splicing
Study establish that the shk mutation, previously localized to chromosome 17, is a quaking (qk) allele consisting of a 105-nucleotide insertion in the qk regulatory region that decreases qk transcription
These results suggested that QKI5 deficiency contributed to the overactivation of FoxO1 (show FOXO1 Antibodies) in ob/ob animals and subsequently magnified nitrosative stress and endoplasmic reticulum stress.
The study provides evidence that cytoplasmic quaking I-6 acts upstream of hnRNP F (show HNRNPF Antibodies)/H, which forms a novel pathway to control alternative splicing in myelinating glia.
Propose that QKI is a central regulator of VSMC phenotypic plasticity and that intervention in QKI activity can ameliorate pathogenic, fibroproliferative responses to vascular injury.
MicroRNA-214 inhibits angiogenesis by targeting Quaking and reducing angiogenic growth factor release.
establish that p53 directly regulates Quaking (QKI) gene expression, and QKI protein associates with and leads to the stabilization of miR-20a
The QKI RNA-binding proteins regulate oligodendrocyte differentiation by modulating the expression of AIP-1 (show WDR1 Antibodies).
The protein encoded by this gene is an RNA-binding protein that regulates pre-mRNA splicing, export of mRNAs from the nucleus, protein translation, and mRNA stability. The encoded protein is involved in myelinization and oligodendrocyte differentiation and may play a role in schizophrenia. Four transcript variants encoding different isoforms have been found for this gene.
RNA binding protein HQK
, homolog of mouse quaking QKI (KH domain RNA binding protein)
, protein quaking
, quaking homolog, KH domain RNA binding
, RNA binding protein HQK-7B
, quaking protein
, RNA binding/signal transduction protein QkI-2
, QKI, KH domain containing, RNA binding tv1
, QKI-5 protein
, lethal, Chr 17, U Wisconsin 1