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anti-Protein Regulator of Cytokinesis 1 (PRC1) Antibodies

PRC1 encodes a protein that is involved in cytokinesis. Additionally we are shipping PRC1 Proteins (5) and PRC1 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PRC1 9055 O43663
PRC1 233406 Q99K43
PRC1 308761  
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Top anti-PRC1 Antibodies at antibodies-online.com

Showing 10 out of 84 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB Immunohistochemistry of PRC1 in mouse skeletal muscle tissue with PRC1 antibody at 2.5 ug/mL. Western blot analysis of PRC1 in human skeletal muscle tissue lysate with Prc1 antibody at (A) 0.5 ug/ml and (B) 1 ug/mL. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Mouse Un-conjugated BCA 100 μg Log in to see 10 to 12 Days
$211.97
Details
Human Mouse Un-conjugated WB Hela cell extracts were resolved by electrophoresis, transferred to nitrocellulose, and probed with monoclonal antibody reactive against PRC1 (clone 6G2). Proteins were visualized using a goat anti-mouse secondary conjugated to HRP and a chemiluminescence detection system 0.1 mg Log in to see 5 to 7 Days
$427.88
Details
Human Rabbit Un-conjugated IHC (p), WB Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Mouse Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$434.50
Details
Human Mouse Un-conjugated WB   25 μg Log in to see 8 to 10 Days
$522.50
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated ICC, IF, IP, WB   0.1 mg Log in to see 5 to 7 Days
$427.88
Details

PRC1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-PRC1 Antibodies

  1. Human Monoclonal PRC1 Primary Antibody for BCA - ABIN2665339 : Jiang, Jimenez, Wells, Hope, Wahl, Hunter, Fukunaga: PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis. in Molecular cell 1999 (PubMed)
    Show all 2 references for ABIN2665339

More Antibodies against PRC1 Interaction Partners

Xenopus laevis Protein Regulator of Cytokinesis 1 (PRC1) interaction partners

  1. Results mechanistically explain how the two conserved, essential midzone proteins PRC1 and Xklp1 cooperate to constitute a minimal protein module capable of dynamically organizing the core structure of the central anaphase spindle.

Human Protein Regulator of Cytokinesis 1 (PRC1) interaction partners

  1. PP2A (show PPP2R4 Antibodies)-B55 (show MINK1 Antibodies) dephosphorylates PRC1 at the metaphase to anaphase transition. This activity is regulated by the Greatwall (MASTL (show MASTL Antibodies)) kinase and its substrate ENSA (show ENSA Antibodies), explaining the timing of PRC1 activation in anaphase.

  2. PRC1 complexes isolated from human cells contain multiple kinesins KIF4A (show KIF4A Antibodies), Kif20A (show KIF20A Antibodies), KIF23 (show KIF23 Antibodies) and KIF14 (show KIF14 Antibodies).

  3. PRC1 is a docking partner for the Polo kinase (show PLK1 Antibodies) Plk1 (show PLK1 Antibodies) in anaphase cells. During metaphase this is inhibited by Cdk1 (show CDK1 Antibodies)-cyclin B phosphorylation at T470 and T481.

  4. The presence of CBX4 or CBX8-GFP in the same focus had a minor impact on BMI1 and RING1 recovery kinetics.

  5. Study finds that frictional forces increase nonlinearly with microtubule-associated proteins (MAP) velocity across microtubules and depend on filament polarity, with NuMA's friction being lower when moving toward minus ends, EB1 (show MAPRE2 Antibodies)'s lower toward plus ends, and PRC1's exhibiting no directional preference.

  6. Studies reveal how interactions between the conserved nonmotor MAP, PRC1, and the motor protein, kinesin-4, generate filament length-dependent tags at microtubule plus ends. PRC1 tags ends of microtubules in dividing cells and the size of these tags increases linearly with filament length.

  7. Different PRC1 paralog family members have nonredundant and locus-specific gene regulatory activities that are essential for human hematopoiesis.

  8. findings suggest that PRC1 is regulated by Plk1 (show PLK1 Antibodies), rather than Cdk1 (show CDK1 Antibodies) as previously proposed, because its activity must be spatiotemporally regulated both preanaphase and postanaphase, and Cdk1 (show CDK1 Antibodies) activity is too binary for this purpose

  9. Two distinct mechanisms are involved in CBX2 (show CBX2 Antibodies)-mediated gene silencing. The short CBX2 (show CBX2 Antibodies)-2 isoform would repress the transcription in a PRC1-independent fashion, whereas gene repression by the long CBX2 (show CBX2 Antibodies)-1 isoform is mediated by the PRC1 protein complex.

  10. Cells depleted of PRC1 failed to form a polarized microtubule array or ectopic furrows following mitotic exit, and recruitment of Aurora B kinase (show AURKB Antibodies), male germ cell Rac GTPase-activating protein (show ARHGAP32 Antibodies), and RhoA (show RHOA Antibodies) to the cortex was impaired.

Mouse (Murine) Protein Regulator of Cytokinesis 1 (PRC1) interaction partners

  1. our findings show that PRC1 mediates gene repression by combining multiple and different effector mechanisms, of which H2A ubiquitination is a major contributor

PRC1 Antigen Profile

Protein Summary

This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with PRC1

  • protein regulator of cytokinesis 1 (PRC1) antibody
  • protein regulator of cytokinesis 1a (prc1a) antibody
  • protein regulator of cytokinesis 1 (prc1) antibody
  • protein regulator of cytokinesis 1b (prc1b) antibody
  • protein regulator of cytokinesis 1 (CNC07120) antibody
  • protein regulator of cytokinesis 1 (Prc1) antibody
  • ASE1 antibody
  • cb212 antibody
  • D7Ertd348e antibody
  • MGC68845 antibody
  • prc1 antibody
  • prc1l antibody
  • zgc:55664 antibody
  • zgc:55982 antibody
  • zgc:86918 antibody

Protein level used designations for PRC1

protein regulator of cytokinesis 1 , anaphase spindle elongation 1 homolog , protein regulating cytokinesis 1

GENE ID SPECIES
100069001 Equus caballus
259194 Danio rerio
380562 Xenopus laevis
393203 Danio rerio
770336 Gallus gallus
3256388 Cryptococcus neoformans var. neoformans JEC21
100012273 Monodelphis domestica
100216075 Xenopus (Silurana) tropicalis
9055 Homo sapiens
233406 Mus musculus
308761 Rattus norvegicus
767818 Bos taurus
488742 Canis lupus familiaris
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