anti-Protein Regulator of Cytokinesis 1 (PRC1) Antibodies

PRC1 encodes a protein that is involved in cytokinesis. Additionally we are shipping PRC1 Proteins (6) and PRC1 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PRC1 9055 O43663
PRC1 233406 Q99K43
PRC1 308761  
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Top anti-PRC1 Antibodies at antibodies-online.com

Showing 10 out of 88 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Human Mouse Un-conjugated WB 100 μg Log in to see 7 to 9 Days
$434.50
Details
Human Mouse Un-conjugated ICC, IF, IP, WB Immunocytochemistry/Immunofluorescence: PRC1 Antibody (16F2) [ABIN2616008] - Analysis of PRC1 using PRC1 Monoclonal Antibody (16F2) shows staining in A2058 Cells. PRC1 (green), F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with an antibody recognizing PRC1 at a dilution of 1:100 over night at 4C, washed with PBS and incubated with a DyLight-488 conjugated. Immunocytochemistry/Immunofluorescence: PRC1 Antibody (16F2) [ABIN2616008] - Analysis of PRC1 using PRC1 Monoclonal Antibody (16F2) shows staining in Hela Cells. PRC1 (green), F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with an antibody recognizing PRC1 at a dilution of 1:100 over night at 4C, washed with PBS and incubated with a DyLight-488 conjugated. 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Human Mouse Un-conjugated BCA 100 μg Log in to see 10 to 12 Days
$211.97
Details
Human Mouse Un-conjugated WB Hela cell extracts were resolved by electrophoresis, transferred to nitrocellulose, and probed with monoclonal antibody reactive against PRC1 (clone 6G2). Proteins were visualized using a goat anti-mouse secondary conjugated to HRP and a chemiluminescence detection system 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: PRC1 Antibody [NBP2-19925] - Analysis of methanol-fixed A431, using antibody at 1:200 dilution. Western Blot: PRC1 Antibody [NBP2-19925] - Sample (30 ug of whole cell lysate) A: JurKat B: Raji 7. 5% SDS PAGE gel, diluted at 1:1000. 0.1 mL Log in to see 8 to 11 Days
$447.56
Details
Human Rabbit Un-conjugated IHC (p), WB Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
$451.00
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of PRC1 expression in MCF7 (A), Jurkat (B), Hela (C), HepG2 (D) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Cy5.5 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details

PRC1 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-PRC1 Antibodies

  1. Human Monoclonal PRC1 Primary Antibody for BCA - ABIN2665339 : Jiang, Jimenez, Wells, Hope, Wahl, Hunter, Fukunaga: PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis. in Molecular cell 1999 (PubMed)
    Show all 2 references for 2665339

More Antibodies against PRC1 Interaction Partners

Xenopus laevis Protein Regulator of Cytokinesis 1 (PRC1) interaction partners

  1. Results mechanistically explain how the two conserved, essential midzone proteins PRC1 and Xklp1 cooperate to constitute a minimal protein module capable of dynamically organizing the core structure of the central anaphase spindle.

Human Protein Regulator of Cytokinesis 1 (PRC1) interaction partners

  1. study reveals that UbE2E1 (show UBE2E1 Antibodies) is an in vivo E2 for the PRC1 ligase complex and thus plays an important role in the regulation of H2A Lys (show LYZ Antibodies)-119 monoubiquitination

  2. PRC1 is a novel Wnt (show WNT2 Antibodies) target that functions in a positive feedback loop that reinforces Wnt (show WNT2 Antibodies) signalling to promote early Hepatocellular Carcinoma recurrence.

  3. PRC1 rs10520699 and rs11852999 polymorphisms were associated with PRC1 transcript levels, but not with patients survival.

  4. These findings suggest that the aberrant expression of PRC1 may predict biochemical recurrence in men with prostate cancer highlighting its potential as a prognostic marker of this malignancy.

  5. PP2A (show PPP2R4 Antibodies)-B55 (show MINK1 Antibodies) dephosphorylates PRC1 at the metaphase to anaphase transition. This activity is regulated by the Greatwall (MASTL (show MASTL Antibodies)) kinase and its substrate ENSA (show ENSA Antibodies), explaining the timing of PRC1 activation in anaphase.

  6. PRC1 complexes isolated from human cells contain multiple kinesins KIF4A (show KIF4A Antibodies), Kif20A (show KIF20A Antibodies), KIF23 (show KIF23 Antibodies) and KIF14 (show KIF14 Antibodies).

  7. PRC1 is a docking partner for the Polo kinase (show PLK1 Antibodies) Plk1 (show PLK1 Antibodies) in anaphase cells. During metaphase this is inhibited by Cdk1 (show CDK1 Antibodies)-cyclin B phosphorylation at T470 and T481.

  8. The presence of CBX4 or CBX8-GFP in the same focus had a minor impact on BMI1 and RING1 recovery kinetics.

  9. Study finds that frictional forces increase nonlinearly with microtubule-associated proteins (MAP) velocity across microtubules and depend on filament polarity, with NuMA's friction being lower when moving toward minus ends, EB1 (show MAPRE2 Antibodies)'s lower toward plus ends, and PRC1's exhibiting no directional preference.

  10. Studies reveal how interactions between the conserved nonmotor MAP, PRC1, and the motor protein, kinesin-4, generate filament length-dependent tags at microtubule plus ends. PRC1 tags ends of microtubules in dividing cells and the size of these tags increases linearly with filament length.

Mouse (Murine) Protein Regulator of Cytokinesis 1 (PRC1) interaction partners

  1. Pcgf6 (show PCGF6 Antibodies) is essential for recruitment of PRC1.6 to chromatin. Our results reveal a previously uncharacterized, H2AK119ub1-independent chromatin assembly associated with PRC1.6 complex

  2. The data reveal how the interplay between PRC1, ncRNA and Mediator complexes controls pluripotency and cellular differentiation.

  3. our findings show that PRC1 mediates gene repression by combining multiple and different effector mechanisms, of which H2A ubiquitination is a major contributor

PRC1 Antigen Profile

Protein Summary

This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with PRC1

  • protein regulator of cytokinesis 1 (PRC1) antibody
  • protein regulator of cytokinesis 1a (prc1a) antibody
  • protein regulator of cytokinesis 1 (prc1) antibody
  • protein regulator of cytokinesis 1b (prc1b) antibody
  • protein regulator of cytokinesis 1 (CNC07120) antibody
  • protein regulator of cytokinesis 1 (Prc1) antibody
  • ASE1 antibody
  • cb212 antibody
  • D7Ertd348e antibody
  • MGC68845 antibody
  • prc1 antibody
  • prc1l antibody
  • zgc:55664 antibody
  • zgc:55982 antibody
  • zgc:86918 antibody

Protein level used designations for PRC1

protein regulator of cytokinesis 1 , anaphase spindle elongation 1 homolog , protein regulating cytokinesis 1

GENE ID SPECIES
100069001 Equus caballus
259194 Danio rerio
380562 Xenopus laevis
393203 Danio rerio
770336 Gallus gallus
3256388 Cryptococcus neoformans var. neoformans JEC21
100012273 Monodelphis domestica
100216075 Xenopus (Silurana) tropicalis
9055 Homo sapiens
233406 Mus musculus
308761 Rattus norvegicus
767818 Bos taurus
488742 Canis lupus familiaris
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