anti-Protein S (Alpha) (PROS1) Antibodies

PROS1 encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. Additionally we are shipping PROS1 Kits (24) and PROS1 Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PROS1 5627 P07225
PROS1 19128 Q08761
PROS1 81750  
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Top anti-PROS1 Antibodies at antibodies-online.com

Showing 10 out of 101 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB <b>WB Suggested Anti-PROS1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Human Muscle Immunohistochemistry with Liver tissue at an antibody concentration of 5µg/ml using anti-PROS1 antibody (ARP56097_P050) 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Pros1 Antibody Titration: 1.0 ug/ml Positive Control: Rat Muscle 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: Protein S Antibody [NBP1-87218] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted) Immunohistochemistry-Paraffin: Protein S Antibody [NBP1-87218] - Staining of human colon shows positivity in plasma. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Bat Rabbit Un-conjugated IHC (p), WB Anti-PROS1 antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959013 concentration 5 ug/ml. 50 μg Log in to see 7 to 9 Days
$676.50
Details
Chicken Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Western Blot: Protein S/PROS1 Antibody [NBP1-31375] - Sample (30 ug of whole cell lysate) A: 293T 7. 5% SDS PAGE; antibody diluted at 1:1000. Immunocytochemistry/Immunofluorescence: Protein S/PROS1 Antibody [NBP1-31375] - Analysis of HeLa, using NBP1-31375 at 1:200 dilution. 0.1 mL Log in to see 7 to 9 Days
$447.56
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 7 to 9 Days
$610.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: Protein S Antibody [NBP1-87217] - Staining of human cell line U-251MG shows positivity in nuclear membrane. Immunohistochemistry-Paraffin: Protein S Antibody [NBP1-87217] - 4% PFA fixed adult mouse brain stained without antigen retrieval using 0.02% triton permeabilization at a dilution of 1:200. Dylight 488 tagged secondary used for detection. Image provided by verified customer review. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated WB Western blot analysis on human serum using anti- Vitamin K-dependent protein S polyclonal antibody.        100 μL Log in to see 13 to 16 Days
$275.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using protein S (alpha), antibody at 1:200 dilution. WB Image Sample (30 ug of whole cell lysate) A: 293T 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 1 to 2 Days
$358.60
Details

PROS1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-PROS1 Antibodies

  1. Human Polyclonal PROS1 Primary Antibody for IHC, IHC (p) - ABIN4892115 : Ten Kate, Platteel, Mulder, Terpstra, Nicolaes, Reitsma, van der Steege, van der Meer: PROS1 analysis in 87 pedigrees with hereditary protein S deficiency demonstrates striking genotype-phenotype associations. in Human mutation 2008 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal PROS1 Primary Antibody for IHC, IHC (p) - ABIN4347906 : Kato, Nicholson, Neiman, Rantalainen, Holmes, Barrett, Uhlén, Nilsson, Spector, Schwenk: Variance decomposition of protein profiles from antibody arrays using a longitudinal twin model. in Proteome science 2011 (PubMed)

More Antibodies against PROS1 Interaction Partners

Human Protein S (Alpha) (PROS1) interaction partners

  1. we identify PROS1 as a driver of Oral Squamous Cell Carcinoma tumor growth and a modulator of AXL (show AXL Antibodies) expression

  2. The prevalence of PS de fi ciency in the present study was higher than in Western countries and con (show DISP1 Antibodies) fi rms the high prevalence of PS de fi ciency in Asian populations

  3. Patients with type 2 diabetes had significantly lower circulating free protein S than healthy control subjects

  4. In the present study, gene analysis of six unrelated Japanese families diagnosed with congenital protein S deficiency identified five missense mutations in the PROS1 gene - c.757C>T (Ala139Val; A139V), c.1346 G>T (Cys449Phe; C449F), c.1352G>A (Arg451Gln; R451Q), c.1424G>T (Cys475Phe; C475F) and c.1574C>T (Ala525Val; A525V) - and one frameshift mutation, c.2135delA (Asp599ThrfsTer13; D599TfsTer13).

  5. The odds ratio of developing idiopathic fatal pulmonary embolism as a variant carrier for PROS1 is 56.4 (95% CI, 5.3-351.1; P = 0.001).

  6. described a novel PROS1 frameshift mutation, c.74dupA, in a hereditary protein S deficiency family. Interestingly, both of the proband and his mother carried the mutation and had a protein S deficiency, however, only the proband suffered a pulmonary embolism while his mother had no history of any thrombosis, suggesting that a triggering event might have been involved in the thrombus formation.

  7. PROS1 may play an important role in the development of glioblastoma multiforme through cellular proliferation, migration and invasion as well as apoptosis.

  8. analysis of genotype phenotype correlation in PROS1 in a large cohort of adults with suspicion of inherited quantitative protein S deficiency

  9. The immunoabsorption of PON1 (show PON1 Antibodies) from plasma significantly reduced protein S anti-coagulant activity.

  10. A PROS1 c.1486_1490delGATTA mutation on exon 12. appeared to be the primary cause of thrombosis in the family of the present study.

Cow (Bovine) Protein S (Alpha) (PROS1) interaction partners

  1. Activated protein C (show PROC Antibodies)(APC (show APC Antibodies)) combined with protein S(PS) had significant antithrombotic effect. APC (show APC Antibodies) combined with PS prolonged clotting time. Dependence on APC (show APC Antibodies)-cofactor activity of PS for expression of anticoagulant activity by APC (show APC Antibodies).

Mouse (Murine) Protein S (Alpha) (PROS1) interaction partners

  1. Mice overexpressing protein S showed significant improvements in blood glucose level, glucose tolerance, insulin (show INS Antibodies) sensitivity, and insulin (show INS Antibodies) secretion compared with wild-type counterparts. diabetic protein S transgenic mice developed significantly less severe diabetic glomerulosclerosis than controls.

  2. By revealing that neural stem-like cells act within the SVZ neurogenic niche as phagocytes and that the ProS/MerTK (show MERTK Antibodies) path represents an endogenous regulatory mechanism for SVZ cell phagocytic activity

  3. Optimal TAM (show CCNA1 Antibodies) signaling requires coincident TAM (show CCNA1 Antibodies) ligand engagement of both its receptor and the phospholipid phosphatidylserine regulating TAM (show CCNA1 Antibodies) receptor tyrosine kinases Tyro3 (show TYRO3 Antibodies), Axl (show AXL Antibodies), and Mer (show ERH Antibodies) and their ligands Gas6 (show GAS6 Antibodies) and Protein S.

  4. Data indicate that activated T cells express Pros1.

  5. Results demonstrate that Protein S is a Mer (show ERH Antibodies) ligand, and is active in Mer (show ERH Antibodies)-driven phagocytosis in the retina.

  6. A self-regulatory mechanism of Toll (show TLR4 Antibodies)-like receptor signalling through the suppression of Gas6 (show GAS6 Antibodies) and ProS expression is described.

  7. Protein S controls hypoxic/ischemic blood-brain barrier disruption through the TAM (show CCNA1 Antibodies) receptor Tyro3 (show TYRO3 Antibodies) and sphingosine 1-phosphate receptor1.

  8. results demonstrate that ProS is a pleiotropic anticoagulant with activated Protein C (show PROC Antibodies)-independent activities and highlight new roles for ProS in vascular development and homeostasis

  9. Pregnancy causes a decrease in APC (show APC Antibodies) resistance in mice, which can be explained by the elevation of protein S levels and increased TFPI (show TFPI Antibodies) activity in plasma.

PROS1 Antigen Profile

Protein Summary

This gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3.

Gene names and symbols associated with PROS1

  • protein S (pros1) antibody
  • protein S (PROS1) antibody
  • protein S (alpha) (Pros1) antibody
  • protein S (Pros1) antibody
  • AW214361 antibody
  • PROS antibody
  • PS21 antibody
  • PS22 antibody
  • PS23 antibody
  • PS24 antibody
  • PS25 antibody
  • PSA antibody
  • THPH5 antibody
  • THPH6 antibody
  • zgc:154001 antibody

Protein level used designations for PROS1

vitamin K-dependent protein S , protein Sa , vitamin K-dependent plasma protein S , vitamin K-dependent protein S preproprotein

GENE ID SPECIES
768180 Danio rerio
5627 Homo sapiens
397388 Sus scrofa
282006 Bos taurus
100009314 Oryctolagus cuniculus
19128 Mus musculus
81750 Rattus norvegicus
694845 Macaca mulatta
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