anti-Protein Tyrosine Phosphatase, Non Receptor Type 23 (PTPN23) Antibodies

putative protein tyrosine phosphatase based on sequence information, may be involved in signal transduction and\\/or protein amino acid dephosphorylation [RGD, Feb 2006].. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PTPN23 25930 Q9H3S7
PTPN23 104831 Q6PB44
PTPN23 117552  
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Top anti-Protein Tyrosine Phosphatase, Non Receptor Type 23 Antibodies at antibodies-online.com

Showing 10 out of 45 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB PTPN23 Antibody (C-term)  western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the PTPN23 antibody detected the PTPN23 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated WB Western Blot analysis of PTPN23 expression in transfected 293T cell line by PTPN23 MaxPab polyclonal antibody.Lane 1: PTPN23 transfected lysate(63.47 KDa).Lane 2: Non-transfected lysate. 50 μg Log in to see 11 to 12 Days
$430.00
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of mouse eye and rat kidney cells, using PTPN23 antibody. 100 μL Log in to see 16 Days
$460.63
Details
Human Rabbit Un-conjugated IP, WB Western Blot: PTPN23 Antibody [NBP2-36549] - Samples: Whole cell lysate (50 ug) from HeLa, 293T, and Jurkat cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-HD-PTP antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds. Immunoprecipitation: PTPN23 Antibody [NBP2-36549] - Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from HeLa cells prepared using NETN lysis buffer. For blotting immunoprecipitated HD-PTP, it was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes. 100 μL Log in to see 7 to 9 Days
$473.81
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunohistochemistry: PTPN23 Antibody [NBP1-84158] - Staining of human appendix shows cytoplasmic positivity in glandular cells. Immunocytochemistry/Immunofluorescence: PTPN23 Antibody [NBP1-84158] - Analysis of human cell line U-251 MG shows positivity in nucleus but excluded from the nucleoli. Antibody staining is shown in green. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit HRP IHC (p), WB   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL Log in to see 7 to 9 Days
$713.17
Details
Human Rabbit FITC ELISA, WB   200 μL Log in to see 7 to 9 Days
$969.83
Details
Human Rabbit HRP ELISA, WB   200 μL Log in to see 7 to 9 Days
$969.83
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 7 to 9 Days
$969.83
Details

PTPN23 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Protein Tyrosine Phosphatase, Non Receptor Type 23 Antibodies

  1. Human Polyclonal PTPN23 Primary Antibody for WB - ABIN525501 : Kim, Lee, Heynen-Genel, Suyama, Ono, Lee, Ideker, Aza-Blanc, Gleeson: Functional genomic screen for modulators of ciliogenesis and cilium length. in Nature 2010 (PubMed)

More Antibodies against Protein Tyrosine Phosphatase, Non Receptor Type 23 Interaction Partners

Human Protein Tyrosine Phosphatase, Non Receptor Type 23 (PTPN23) interaction partners

  1. The role of HD-PTP/PTPN23 in cancer and tumorigenesis is reviewed.

  2. Results present crystal structures of the coiled-coil domain of the HD-PTP phosphatase and its complex with UBAP1 (show UBAP1 Antibodies). The coiled-coil domain adopts an unexpected open and rigid conformation. The HD-PTP:UBAP1 structure identifies the molecular determinants of the interaction and provides a molecular basis for the specific functional cooperation between HD-PTP and UBAP1 (show UBAP1 Antibodies).

  3. HD-PTP acts as an alternative to ESCRT-II (show VPS28 Antibodies) and VPS20/CHMP6 (show CHMP6 Antibodies) as a link between the ESCRT-I (show VPS28 Antibodies) and those ESCRT-III protein(s) necessary for ILV formation.

  4. Data indicate a regulatory function of non-receptor-type tyrosine phosphatase PTPN23 in maintaining a highly phosphorylated state of survival motor neuron (show SMN1 Antibodies) complex protein SMN (show STMN1 Antibodies).

  5. PTPN23 is a tumor suppressor and that repression of PTPN23 expression by miR (show MLXIP Antibodies)-142-3p plays an important role in the pathogenesis of testicular germ cell tumors.

  6. The ESCRT accessory protein HD-PTP/PTPN23 associates with epidermal growth factor receptor (EGFR (show EGFR Antibodies)) and combines with the deubiquitinating enzyme UBPY/USP8 (show USP8 Antibodies) to transfer EGFR (show EGFR Antibodies) from ESCRT-0 to ESCRT-III and drive EGFR (show EGFR Antibodies) sorting to intralumenal vesicles.

  7. our findings suggest an evolutionarily conserved function of HDPTP-Rab4 (show RAB4A Antibodies) in the regulation of endocytic trafficking, cell adhesion and migration

  8. HD-PTP degradation by calpains might result in the acquisition of a more aggressive phenotype in neoplastic cells.

  9. loss of PTPN23 may increase the activity of SRC (show SRC Antibodies) and the phosphorylation status of the E-cadherin (show CDH1 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling complex to promote tumor growth and invasive behavior in breast cancer

  10. Histidine domain-protein tyrosine phosphatase (show ACP1 Antibodies) interacts with Grb2 (show GRB2 Antibodies) and GrpL (show GRAP2 Antibodies)

Mouse (Murine) Protein Tyrosine Phosphatase, Non Receptor Type 23 (PTPN23) interaction partners

  1. The role of HD-PTP/PTPN23 in cancer and tumorigenesis is reviewed.

  2. HD-PTP affects the intracellular sorting of activated PDGFRbeta and the migration, proliferation and tumorigenicity of cells stimulated by PDGF (show PDGFA Antibodies).

  3. PTPN23 is a tumor suppressor and that repression of PTPN23 expression by miR (show MLXIP Antibodies)-142-3p plays an important role in the pathogenesis of testicular germ cell tumors.

  4. homozygous gene deletion is lethal around embryonic day 9.5, suggesting that Ptpn23 is an essential requirement for early stages of embryonic development

Protein Tyrosine Phosphatase, Non Receptor Type 23 (PTPN23) Antigen Profile

Protein Summary

putative protein tyrosine phosphatase based on sequence information, may be involved in signal transduction and/or protein amino acid dephosphorylation

Gene names and symbols associated with PTPN23

  • protein tyrosine phosphatase, non-receptor type 23 (PTPN23) antibody
  • protein tyrosine phosphatase, non-receptor type 23 (Ptpn23) antibody
  • AI462446 antibody
  • HD-PTP antibody
  • HDPTP antibody
  • Ptp-Td14 antibody

Protein level used designations for PTPN23

His-domain protein tyrosine phosphatase , his domain-containing protein tyrosine phosphatase , protein tyrosine phosphatase TD14 , tyrosine-protein phosphatase non-receptor type 23

GENE ID SPECIES
25930 Homo sapiens
104831 Mus musculus
117552 Rattus norvegicus
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