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Protein Tyrosine Phosphatase, Receptor Type, M Proteins (PTPRM)

The protein encoded by PTPRM is a member of the protein tyrosine phosphatase (PTP) family. Additionally we are shipping Protein Tyrosine Phosphatase, Receptor Type, M Antibodies (60) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PTPRM 5797 P28827
PTPRM 19274 P28828
Rat PTPRM PTPRM 29616  
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Top Protein Tyrosine Phosphatase, Receptor Type, M Proteins at antibodies-online.com

Showing 8 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 69 to 74 Days
$12,906.52
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 69 to 74 Days
$9,050.32
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$803.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Baculovirus infected Insect Cells Human GST tag   50 μg Log in to see 10 to 12 Days
$570.24
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$983.48
Details

PTPRM Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,
Mouse (Murine) ,
,

More Proteins for Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM) Interaction Partners

Human Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM) interaction partners

  1. Study determined that, in addition to the furin (show FURIN Proteins)-processed form of PTPmicro, a pool of 200 kDa full-length PTPmicro exists at the plasma membrane that is cleaved directly by ADAM to generate a larger shed form of the PTPmicro extracellular segment.

  2. Decreased expression of PTPRM in breast cancer is correlated with poor prognosis and inversely correlated with disease-free survival.

  3. Results suggest that miR (show MLXIP Proteins)-221 and -222 regulate glioma tumorigenesis at least in part through the control of PTPmu protein expression.

  4. Loss of protein tyrosine phosphatase (show ACP1 Proteins) receptor type mu is associated with glioma cell migration and progression.

  5. interactions between RPTP-domain1s and RPTP-domain 2s are a common but specific mechanism that is likely to be regulated- domain2s and the wedge structures are crucial determinants of binding specificity, thus regulating cross-talk between RPTPs (show PTPRS Proteins)

  6. RPTPmu may play a role in the regulation of cardiovascular functions

  7. PTPmu may regulate Rho-GTPase-dependent functions of IQGAP1

  8. a 3.1 angstrom crystal structure of the RPTPmu ectodomain that forms a homophilic trans (antiparallel) dimer with an extended and rigid architecture, matching the dimensions of adherens junctions is described

  9. BCCIP (show BCCIP Proteins) is phosphorylated by the Src (show SRC Proteins) tyrosine kinase (show TXK Proteins) and dephosphorylated by the PTPmu tyrosine phosphatase; neurite outgrowth assays suggest that BCCIP (show BCCIP Proteins) and PTPmu are in a common signal transduction pathway.

Mouse (Murine) Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM) interaction partners

  1. histochemical analysis showed that within bone, RPTPmu is expressed exclusively in early-stage osteocytes and therefore is a new marker for osteocytes

  2. differentiation into adipocytes is controlled by RPTPmu

  3. RPTPmu is involved in the mechanotransduction or accessory signaling pathways that control shear stress responses in mesenteric resistance arteries.

Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.

Gene names and symbols associated with PTPRM

  • protein tyrosine phosphatase, receptor type, M, a (ptprma)
  • protein tyrosine phosphatase, receptor type, M (PTPRM)
  • protein tyrosine phosphatase, receptor type, M, b (ptprmb)
  • protein tyrosine phosphatase, receptor type, M (ptprm)
  • protein tyrosine phosphatase, receptor type, M (LOC100356969)
  • protein tyrosine phosphatase, receptor type, M (Ptprm)
  • cb984 protein
  • hR-PTPu protein
  • mKIAA4044 protein
  • p-ptp-mu protein
  • PTPRL1 protein
  • PTPRM protein
  • R-PTP-MU protein
  • r-ptpu protein
  • RPTPM protein
  • RPTPmu protein
  • RPTPU protein
  • zgc:110218 protein

Protein level used designations for PTPRM

receptor-type tyrosine-protein phosphatase mu , protein tyrosine phosphatase, receptor type, M , receptor-type tyrosine-protein phosphatase mu-like , protein tyrosine phosphatase mu , protein tyrosine phosphatase, receptor type, mu polypeptide , protein-tyrosine phosphatase mu , R-PTP-mu , protein tyrosine phosphatase, receptor-type, M , protein tyrosine phosphatase receptor-type M

GENE ID SPECIES
386769 Danio rerio
455298 Pan troglodytes
722426 Macaca mulatta
100000074 Danio rerio
100059664 Equus caballus
100127701 Xenopus (Silurana) tropicalis
100173948 Pongo abelii
100356969 Oryctolagus cuniculus
100397924 Callithrix jacchus
100465579 Ailuropoda melanoleuca
100550127 Meleagris gallopavo
100564083 Anolis carolinensis
100597968 Nomascus leucogenys
5797 Homo sapiens
480203 Canis lupus familiaris
19274 Mus musculus
536092 Bos taurus
29616 Rattus norvegicus
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