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anti-Protein Tyrosine Phosphatase Non-Receptor Type 5 (PTPN5) Antibodies

a putative protein-tyrosine-phosphatase that is found enriched within the striatum.

list all antibodies Gene Name GeneID UniProt
Anti-Mouse PTPN5 PTPN5 19259 P54830
PTPN5 29644 P35234
PTPN5    
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Top anti-Protein Tyrosine Phosphatase Non-Receptor Type 5 Antibodies at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Reactivity Host Conjugate Application Quantity Supplier Delivery Price Details
Rat Mouse Un-conjugated IP, IHC, WB 100 μg Log in to see 11 to 16 Days
$697.71
Details
Rat Mouse Un-conjugated IP, WB 100 μL Log in to see 11 to 16 Days
$491.86
Details
Human Mouse Un-conjugated IHC, WB 50 μL Log in to see 11 to 16 Days
$658.43
Details
Rat Mouse Un-conjugated IC, IHC, WB 100 μL Log in to see 11 to 16 Days
$529.57
Details

PTPN5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Rat (Rattus)


Human


More Antibodies against Protein Tyrosine Phosphatase Non-Receptor Type 5 Interaction Partners

Mouse (Murine) Protein Tyrosine Phosphatase Non-Receptor Type 5 (PTPN5) interaction partners

  1. STEP61 regulates BDNF (show BDNF Antibodies) expression, with implications for cognitive functioning in CNS disorders.

  2. The study provides further insight into the mechanisms of regulation of STEP61 and also offers a molecular basis for the Zn(2+)-induced sustained activation of ERK2 (show MAPK1 Antibodies).

  3. These results indicate that STEP61 is a novel substrate of parkin (show PARK2 Antibodies), although further studies are necessary to determine whether elevated STEP61 levels directly contribute to the pathophysiology of PD.

  4. Abeta (show APP Antibodies) regulating STEP61 activity is mediated by Abeta (show APP Antibodies) binding to alpha7 nAChRs

  5. Increased STEP and calpain activation contribute to altered NMDAR (show GRIN1 Antibodies) localization in an Huntington's disease mouse model.

  6. genetically reducing STEP significantly diminishes seizures and restores select social and nonsocial anxiety-related behaviors in Fmr1 (show FMR1 Antibodies)(KO) mice

  7. the first study to identify Pyk2 (show PTK2B Antibodies) as a substrate for STEP.

  8. Increased STEP61 plays a role in amyloid Abeta (show APP Antibodies)-mediated internalization of the (AMPAR) subunits GluA1 (show GRIA1 Antibodies)/GluA2 (show GRIA2 Antibodies) (formerly GluR1 (show GRIA1 Antibodies)/GluR2 (show GRIA2 Antibodies)).

  9. STEP pathway is severely downregulated in the presence of mutant huntingtin (show HTT Antibodies) and may participate in compensatory mechanisms activated by striatal neurons that lead to resistance to excitotoxicity.

  10. Electrical stimulation of the hippocampal-entorhinal cortex pathway in STEP knockout mice resulted in less activation of the dentate gyrus granule cell layer (GCL), but greater activation of the hilus in STEP knockouts, compared with heterozygous slices.

Protein Tyrosine Phosphatase Non-Receptor Type 5 (PTPN5) Antigen Profile

Protein Summary

May regulates the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors (By similarity).

Gene names and symbols associated with PTPN5

  • protein tyrosine phosphatase, non-receptor type 5 (Ptpn5) antibody
  • STEP antibody

Protein level used designations for PTPN5

neural-specific protein-tyrosine phosphatase , striatum-enriched protein-tyrosine phosphatase , tyrosine-protein phosphatase non-receptor type 5 , protein-tyrosine phosphatase striatum-enriched , protein-tyrosine-phosphatase non-receptor 5

GENE ID SPECIES
19259 Mus musculus
29644 Rattus norvegicus
Selected quality suppliers for anti-Protein Tyrosine Phosphatase Non-Receptor Type 5 (PTPN5) Antibodies
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