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anti-Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3) Antibodies

The protein encoded by PTP4A3 belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). Additionally we are shipping PTP4A3 Proteins (15) and PTP4A3 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PTP4A3 19245 Q9D658
PTP4A3 11156 O75365
PTP4A3 362930  
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Top anti-PTP4A3 Antibodies at antibodies-online.com

Showing 10 out of 74 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-PTP4A3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 293T cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-PTP4A3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: ACHN cell lysate WB Suggested Anti-PTP4A3  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: ACHN cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 0.1 mL Log in to see 6 to 8 Days
$308.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of PTP4A3 C-term (ABIN392855) in MCF-7 and 293 cell line lysates (35 µg/lane). PTP4A3 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$253.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (42.39 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Mouse Un-conjugated WB The monoclonal antibody anti-PRL3 (ABIN387832) is used in Western blot to detect PRL3 in 293 cells transfected with PRL3. 400 μL Log in to see 10 to 11 Days
$324.50
Details

PTP4A3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)
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Rat (Rattus)
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Top referenced anti-PTP4A3 Antibodies

  1. Human Polyclonal PTP4A3 Primary Antibody for EIA, WB - ABIN360768 : Kato, Semba, Miskad, Seo, Kasuga, Yokozaki: High expression of PRL-3 promotes cancer cell motility and liver metastasis in human colorectal cancer: a predictive molecular marker of metachronous liver and lung metastases. in Clinical cancer research : an official journal of the American Association for Cancer Research 2004 (PubMed)
    Show all 9 references for ABIN360768

  2. Human Polyclonal PTP4A3 Primary Antibody for WB - ABIN363058 : Matter, Estridge, Zhang, Belagaje, Stancato, Dixon, Johnson, Bloem, Pickard, Donaghue, Acton, Jeyaseelan, Kadambi, Vlahos: Role of PRL-3, a human muscle-specific tyrosine phosphatase, in angiotensin-II signaling. in Biochemical and biophysical research communications 2001 (PubMed)
    Show all 2 references for ABIN363058

  3. Human Polyclonal PTP4A3 Primary Antibody for WB - ABIN401548 : Wang, Kirby, Herbst: The tyrosine phosphatase PRL-1 localizes to the endoplasmic reticulum and the mitotic spindle and is required for normal mitosis. in The Journal of biological chemistry 2002 (PubMed)
    Show all 2 references for ABIN401548

  4. Human Polyclonal PTP4A3 Primary Antibody for EIA, WB - ABIN360769 : Wu, Zeng, Zhang, Zhao, Sha, Ge, Zhang, Gao, Xu: Phosphatase of regenerating liver-3 promotes motility and metastasis of mouse melanoma cells. in The American journal of pathology 2004 (PubMed)
    Show all 2 references for ABIN360769

  5. Human Polyclonal PTP4A3 Primary Antibody for ELISA, WB - ABIN564844 : Fromont, Godet, Peyret, Irani, Celhay, Rozet, Cathelineau, Cussenot: 8q24 amplification is associated with Myc expression and prostate cancer progression and is an independent predictor of recurrence after radical prostatectomy. in Human pathology 2013 (PubMed)

  6. Chicken Polyclonal PTP4A3 Primary Antibody for WB - ABIN2784453 : Liang, Luo, Dong, Walls, Liang, Jiang, Sanford, Wek, Zhang: Translational control of C-terminal Src kinase (Csk) expression by PRL3 phosphatase. in The Journal of biological chemistry 2008 (PubMed)

More Antibodies against PTP4A3 Interaction Partners

Mouse (Murine) Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3) interaction partners

  1. Results demonstrate that Ptp4a3 contributes to the malignant phenotype of tumor-initiating cells.

  2. PRL-3 (show STAT3 Antibodies) protein was significantly reduced in mouse STAT3 (show STAT3 Antibodies)-knockout liver cells compared with (show STAT3 Antibodies)STAT3-wild type counterparts, and e (show RUNX1 Antibodies)ctopic expression of STAT3 in these ce (show STAT3 Antibodies)lls led to a pronounced increase in PRL-3 protein.

  3. Data indicate that Mycobacterium tuberculosis T cell stimulatory epitope (MT) is a potentially effective molecular adjuvant in preparation of monoclonal antibody (mAb) specific for phosphatase of regenerating liver-3 (PRL-3).

  4. These findings strongly support a role for PTP4A3 as an important contributor to endothelial cell function and as a multimodal target for cancer therapy and mitigating VEGF-regulated angiogenesis.

  5. the first definitive evidence implicating Ptp4a3 in colon tumorigenesis

  6. role of PTP4A3 in acute myeloid leukemia (show BCL11A Antibodies)

  7. PTP4A3 was identified as a novel negative regulator of LPS (show TLR4 Antibodies)-induced LITAF/TNF-alpha production.

  8. PRL-3 was highly expressed in metastatic melanoma B16-BL6 cells but not in its lowly metastatic parental cell line, B16 cells

  9. PRL-3-expressing cells rapidly induce metastatic tumor formation in lung

  10. PRL-3 was shown to be expressed in the total mouse bone marrow fraction and more intensely in the Ter119-positive (pre-erythrocyte) fraction but not in the CD61 (show ITGB3 Antibodies)-positive (megakaryocyte)fraction.

Human Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3) interaction partners

  1. PRL-3 provides a strategic survival advantage to tumour cells via its effects on mTOR (show FRAP1 Antibodies).

  2. Promotes uveal melanoma aggressiveness via membrane accumulation of matrix metalloproteinase 14 (MMP14 (show MMP14 Antibodies))

  3. Our findings suggested that PRL-3 genomic gain may represent an aggressive phenotype of primary colorectal cancer

  4. Examination of clinical samples confirmed that USP4 (show USP4 Antibodies) expression positively correlates with PRL-3 protein expression, but not mRNA transcript levels.

  5. PTP4A3 over expression independently predicted the metastasis and outcome of upper tract urothelial carcinoma, which was even more important in organ confined disease.

  6. Data inticate that heat shock protein 60 (HSP60 (show HSPD1 Antibodies)) interacted constitutively with NKG2D (show KLRK1 Antibodies) ligand ULBP2 (show ULBP2 Antibodies) and phosphatase of regenerating liver 3 (PRL-3) regulated HSP60 (show HSPD1 Antibodies) tyrosine phosphorylation.

  7. These studies reveal a critical role of autophagy in PTP4A3-driven cancer progression.

  8. miR (show MLXIP Antibodies)-495 methylation-associated silencing inhibits the migration and invasion of human gastric cancer cells by directly targeting PRL-3

  9. Tumor-associated macrophages participate in the metastasis of CRC (show CALR Antibodies) induced by PRL-3 through secretion of IL-6 (show IL6 Antibodies) and IL-8 (show IL8 Antibodies) in a KCNN4 (show KCNN4 Antibodies) dependent manner.

  10. STAT3 (show STAT3 Antibodies) binds to the -201 to -210 region of PRL-3. STAT3 (show STAT3 Antibodies) functionally regulates PRL-3. STAT3 (show STAT3 Antibodies) core signature was enriched in AML (show RUNX1 Antibodies) with high PRL-3 expression. The STAT3 (show STAT3 Antibodies)/PRL-3 regulatory loop contributes to the pathogenesis of AML (show RUNX1 Antibodies).

Xenopus laevis Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3) interaction partners

  1. Data show that protein-tyrosine phosphatase (show ACP1 Antibodies) PRP4A3 (prl3) and van gogh like1 (vangl1 (show Vangl1 Antibodies)) are Necessary Components in prohibitin1 (phb1 (show PHB Antibodies)) dependent neural crest specification.

  2. PTP4A3 is required for cephalic neural crest migration in vivo during embryonic development.

PTP4A3 Antigen Profile

Protein Summary

The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist.

Gene names and symbols associated with PTP4A3

  • protein tyrosine phosphatase type IVA, member 3 (PTP4A3) antibody
  • protein tyrosine phosphatase type IVA, member 3 (ptp4a3) antibody
  • protein tyrosine phosphatase type IVA, member 3 (LOC100342107) antibody
  • protein tyrosine phosphatase 4a3 (Ptp4a3) antibody
  • protein tyrosine phosphatase type IVA, member 2 (PTP4A2) antibody
  • protein tyrosine phosphatase type IVA, member 3 (Ptp4a3) antibody
  • AV088979 antibody
  • pPtp4a3 antibody
  • prl-3 antibody
  • PRL-R antibody
  • prl3 antibody
  • PTP4A3 antibody
  • ptpcaax3 antibody
  • wu:fc54b05 antibody
  • wu:fv52d11 antibody
  • zgc:77109 antibody

Protein level used designations for PTP4A3

protein tyrosine phosphatase type IVA, member 3 , protein tyrosine phosphatase type IVA 3 , protein-tyrosine phosphatase 4a3 , protein-tyrosine phosphatase of regenerating liver 3 , potentially prenylated protein tyrosine phosphatase , protein tyrosine phosphatase 4a3 , PRL-3 , fc54b05 , fv52d11 , xPRL-3

GENE ID SPECIES
737820 Pan troglodytes
100216017 Xenopus (Silurana) tropicalis
100342107 Oryctolagus cuniculus
19245 Mus musculus
614435 Bos taurus
11156 Homo sapiens
362930 Rattus norvegicus
406460 Danio rerio
432351 Xenopus laevis
768713 Gallus gallus
606961 Canis lupus familiaris
100137722 Bos taurus
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