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Protein Z, Vitamin K-Dependent Plasma Glycoprotein Proteins (PROZ)

PROZ encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. Additionally we are shipping PROZ Antibodies (28) and PROZ Kits (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat PROZ PROZ 306608  
PROZ 66901 Q9CQW3
PROZ 8858 P22891
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Top PROZ Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,094.67
Details

PROZ Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Protein Z, Vitamin K-Dependent Plasma Glycoprotein (PROZ) Interaction Partners

Mouse (Murine) Protein Z, Vitamin K-Dependent Plasma Glycoprotein (PROZ) interaction partners

  1. Letter: protein Z is not a typical acute phase reactant.

  2. PZ and ZPI (show SERPINA10 Proteins) deficiency would be associated with a modest thrombotic risk with ZPI (show SERPINA10 Proteins) deficiency producing a more severe phenotype.

Human Protein Z, Vitamin K-Dependent Plasma Glycoprotein (PROZ) interaction partners

  1. Results show the energetic basis of the Z-dependent protease inhibitor (ZPI (show SERPINA10 Proteins))-protein Z (PZ) interaction and suggest an important role for ZPI (show SERPINA10 Proteins) Lys (show LYZ Proteins)-239 in PZ catalytic action.

  2. The unbalance between PZ and ZPI (show SERPINA10 Proteins) in plasma samples from patients with Colorectal Cancer or Pancreatic Cancer is not only related to an inflammatory state but could also results from an ectopic synthesis of these proteins by the cancer cells.

  3. Protein Z EGF2 subdomain constitutes an interactive-site for ZPI (show SERPINA10 Proteins) protein.

  4. Protein Z/protein Z-dependent protease inhibitor (show SERPINA10 Proteins) and Fxa (show F10 Proteins) expression in human gastric cancer cells indicate that these proteins may play a role in anticoagulant events at the tumor tissue.

  5. active mutations of PZ in the serine protease (show F2 Proteins) structural domain were found in women with fetal loss

  6. Data suggest role for complex of PZ with ZPI (PZ-dependent protease inhibitor (show SERPINA10 Proteins)) in pregnancy maintenance; this is highlighted by progressive elevation in PZ levels in first trimester of gestation which then steadily decline toward delivery. [REVIEW]

  7. the PZ/ZPI (show SERPINA10 Proteins) complex may play some modulating role in hemophilia A

  8. 74 patients a protein Z deficiency has been found.

  9. PZ can be a cofactor associated with an increased bleeding tendency in patients with AML (show RUNX1 Proteins).

  10. expression of PROZ in PLC/PRF/5 cells increased cell viability and clonogenicity compared to mock-transfected cells.

PROZ Protein Profile

Protein Summary

This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with PROZ

  • protein Z, vitamin K-dependent plasma glycoprotein (Proz)
  • protein Z, vitamin K-dependent plasma glycoprotein (PROZ)
  • hypothetical LOC558106 (LOC558106)
  • 1300015B06Rik protein
  • PZ protein

Protein level used designations for PROZ

vitamin K-dependent protein Z , protein Z, vitamin K-dependent plasma glycoprotein , hypothetical LOC558106 , protein Z, vitamin K-dependent plasma protein

GENE ID SPECIES
306608 Rattus norvegicus
418746 Gallus gallus
467342 Pan troglodytes
558106 Danio rerio
100137444 Papio anubis
66901 Mus musculus
617946 Bos taurus
8858 Homo sapiens
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