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Protein tyrosine Phosphatase, Non-Receptor Type 5 (Striatum-Enriched) (PTPN5) ELISA Kits

May regulates the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors (By similarity).. Additionally we are shipping Protein tyrosine Phosphatase, Non-Receptor Type 5 (Striatum-Enriched) Antibodies (82) and Protein tyrosine Phosphatase, Non-Receptor Type 5 (Striatum-Enriched) Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat PTPN5 PTPN5 29644 P35234
Anti-Mouse PTPN5 PTPN5 19259 P54830
Anti-Human PTPN5 PTPN5 84867 P54829
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More ELISA Kits for Protein tyrosine Phosphatase, Non-Receptor Type 5 (Striatum-Enriched) Interaction Partners

Mouse (Murine) Protein tyrosine Phosphatase, Non-Receptor Type 5 (Striatum-Enriched) (PTPN5) interaction partners

  1. STEP61 regulates BDNF (show BDNF ELISA Kits) expression, with implications for cognitive functioning in CNS disorders.

  2. The study provides further insight into the mechanisms of regulation of STEP61 and also offers a molecular basis for the Zn(2+)-induced sustained activation of ERK2 (show MAPK1 ELISA Kits).

  3. These results indicate that STEP61 is a novel substrate of parkin (show PARK2 ELISA Kits), although further studies are necessary to determine whether elevated STEP61 levels directly contribute to the pathophysiology of PD.

  4. Abeta (show APP ELISA Kits) regulating STEP61 activity is mediated by Abeta (show APP ELISA Kits) binding to alpha7 nAChRs

  5. Increased STEP and calpain activation contribute to altered NMDAR (show GRIN1 ELISA Kits) localization in an Huntington's disease mouse model.

  6. genetically reducing STEP significantly diminishes seizures and restores select social and nonsocial anxiety-related behaviors in Fmr1 (show FMR1 ELISA Kits)(KO) mice

  7. the first study to identify Pyk2 (show PTK2B ELISA Kits) as a substrate for STEP.

  8. Increased STEP61 plays a role in (show APP ELISA Kits)amyloid Abeta-mediated internalization of th (show GRIA1 ELISA Kits)e (AMP (show GRIA2 ELISA Kits)AR) subuni (show GRIN1 ELISA Kits)ts GluA1/GluA2 (formerly GluR1/GluR2).

  9. STEP pathway is severely downregulated in the presence of mutant huntingtin (show HTT ELISA Kits) and may participate in compensatory mechanisms activated by striatal neurons that lead to resistance to excitotoxicity.

  10. Electrical stimulation of the hippocampal-entorhinal cortex pathway in STEP knockout mice resulted in less activation of the dentate gyrus granule cell layer (GCL), but greater activation of the hilus in STEP knockouts, compared with heterozygous slices.

Human Protein tyrosine Phosphatase, Non-Receptor Type 5 (Striatum-Enriched) (PTPN5) interaction partners

  1. A rare missense variant in the PTPN5 gene (rs56234898; minor allele frequency 1.5%) was significantly associated with decreased severity of Post-Burn Hypertrophic Scarring(P = 1.3x10-6).

  2. The results imply a model in which PTPN5 may play a role in normal cognitive functioning and contribute to aspects of the neuropathology of schizophrenia.

  3. This study identified a novel role for PTPN5 in mediating the development of stress-related cognitive and morphological changes.

  4. STEP(61kDa) is required for Abeta (show APP ELISA Kits) transgene-mediated internalization of GluA1 (show GRIA1 ELISA Kits)/GluA2 (show GRIA2 ELISA Kits) glutamate (show GRIN1 ELISA Kits) receptors in a transgenic mousemodel.

  5. STEP contributes to aspects of the pathophysiology in Alzheimer's disease; loss of GluN1 (show GRIN1 ELISA Kits)/GluN2B (show GRIN2B ELISA Kits) subunits from neuronal membranes and Abeta (show APP ELISA Kits)-mediated NMDAR (show GRIN1 ELISA Kits) internalization are discussed

  6. determined high-resolution structures of all of the human family members of Mitogen-Activated Protein Kinase (show MAPK1 ELISA Kits)-specific protein tyrosine phosphatases

Protein tyrosine Phosphatase, Non-Receptor Type 5 (Striatum-Enriched) (PTPN5) Antigen Profile

Antigen Summary

May regulates the activity of several effector molecules involved in synaptic plasticity and neuronal cell survival, including MAPKs, Src family kinases and NMDA receptors (By similarity).

Gene names and symbols associated with PTPN5

  • protein tyrosine phosphatase, non-receptor type 5 (ptpn5) antibody
  • protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) (PTPN5) antibody
  • protein tyrosine phosphatase, non-receptor type 5 (Ptpn5) antibody
  • PTPSTEP antibody
  • Step antibody

Protein level used designations for PTPN5

protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) , tyrosine-protein phosphatase non-receptor type 5 , neural-specific protein-tyrosine phosphatase , protein-tyrosine phosphatase striatum-enriched , protein-tyrosine-phosphatase non-receptor 5 , striatum-enriched protein-tyrosine phosphatase

GENE ID SPECIES
559524 Danio rerio
423085 Gallus gallus
615850 Bos taurus
29644 Rattus norvegicus
19259 Mus musculus
84867 Homo sapiens
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