anti-Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13) Antibodies

The protein encoded by PTPN13 is a member of the protein tyrosine phosphatase (PTP) family. Additionally we are shipping PTPN13 Proteins (6) and PTPN13 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PTPN13 5783 Q12923
PTPN13 19249 Q64512
PTPN13 498331  
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Top anti-PTPN13 Antibodies at antibodies-online.com

Showing 10 out of 54 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from LOVO cells, using FAP-1 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using FAP-1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p)   100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (fro), IHC (p), IP, WB Immunohistochemistry-Paraffin: PTPN13/PTPL1 Antibody [ABIN43485939] - Formalin-fixed, paraffin embedded ovarian carcinoma cores from a tissue microarray at 1:2000. A-D, samples are from four different patients. A1-D1 are high magnification images from A-D, respectively. Hematoxylin-eosin counterstain. Immunohistochemistry-Paraffin: PTPN13/PTPL1 Antibody [ABIN43485939] - Analysis of PTPN13/PTPL1 in cell lines using this antibody at 1:2000. In ovarian carcinoma cell lines PTPN13/PTPL1 expression was detected in SK-OV-3 and OVCAR-3, but not in BG-1 or HEY. Human 293 kidney and Jurkat T cell lines were used as positive and negative controls, respectively. 0.05 mL Log in to see 7 to 9 Days
$381.94
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (fro), IHC (p), IP, WB 50 μL Log in to see 7 to 9 Days
$507.83
Details
Human Rabbit Un-conjugated IHC (p) Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with PTPN13at 10 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Human Kidney (formalin-fixed, paraffin-embedded) stained with PTPN13at 10 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. 0.25 mL Log in to see 11 to 13 Days
$542.85
Details
Human Chicken Un-conjugated WB 0.05 mg Log in to see 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated IHC (p), ELISA Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with PTPN13 antibody ABIN214667 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7 to 9 Days
$451.00
Details
Human Rabbit Un-conjugated IHC, ELISA 0.05 mg Log in to see 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated IHC (p), IHC, ELISA Immunohistochemistry-Paraffin: PTPN13/PTPL1 Antibody [NBP1-02579] - Staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 0.05 mg Log in to see 7 to 9 Days
$447.56
Details

PTPN13 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-PTPN13 Antibodies

  1. Human Polyclonal PTPN13 Primary Antibody for ICC, IF - ABIN4348593 : Meinhold-Heerlein, Stenner-Liewen, Liewen, Kitada, Krajewska, Krajewski, Zapata, Monks, Scudiero, Bauknecht, Reed: Expression and potential role of Fas-associated phosphatase-1 in ovarian cancer. in The American journal of pathology 2001 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal PTPN13 Primary Antibody for IF (p), IHC (p) - ABIN714341 : Evrard, Lecce, Michelis, Nomura-Kitabayashi, Pandey, Purushothaman, dEscamard, Li, Hadri, Fujitani, Moreno, Benard, Rimmele, Cohain, Mecham, Randolph, Nabel, Hajjar, Fuster, Boehm, Kovacic: Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability. in Nature communications 2016 (PubMed)

More Antibodies against PTPN13 Interaction Partners

Human Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13) interaction partners

  1. Fap1 inhibition increased Fas sensitivity and decreased beta-catenin activity in human CD34+ CML cells

  2. the crystal structure of the PTP-Bas PDZ1 domain at 1.6 A resolution, is reported.

  3. PTPN13 overexpression significantly inhibited the progression of HCC (show FAM126A Antibodies) cells.

  4. Mutation in PTPN13 gene is associated with gastric cancer peritoneal carcinomatosis.

  5. This work studied heat diffusion in the well-known PDZ (show INADL Antibodies)-2 protein, and confirmed that this protein has two cognate allosteric pathways and that heat flows preferentially through these.

  6. Necl-4 serves as a novel regulator for contact inhibition of cell movement and proliferation cooperatively with the VEGF receptor and PTPN13

  7. A PDZ (show INADL Antibodies)-mediated interaction of PTPN13 and PTEN (show PTEN Antibodies) is described with possible relevance for tumor suppression.

  8. The effect of the viscogens sucrose, and glycerol on the kinetic response of a photoperturbed PTPN13 is investigated.

  9. A comprehensive molecular dynamics simulation study of the PDZ2 domain of human tyrosine phosphatase 1E in the ligand-bound and -free state, as well as the photoswitchable protein in the cis (show CISH Antibodies) and trans states of the photoswitch

  10. Thus, our results suggest a previously unknown Stat3-PTPN13 molecular network controlling squamous cell lung carcinoma development

Mouse (Murine) Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13) interaction partners

  1. contributions of Fap1 to tyrosine kinase inhibitors (TKI)resistance, CML blast crisis, and relapse after TKI discontinuation

  2. The data show that the levels of PTPN13 and beta-catenin (show CTNNB1 Antibodies) must be strictly regulated by extracellular signaling to regulate hematopoietic stem cells attachment to the bone marrow niche and the balance between proliferation and quiescence.

  3. The study presents a detailed kinetics analysis of the interaction between PTP-BL PDZ2 domain and a peptide mimicking the PDZ (show INADL Antibodies) binding motif of APC (show APC Antibodies).

  4. SDCCAG3 (show SDCCAG3 Antibodies) forms a complex with PTPN13. Interaction of SDCCAG3 (show SDCCAG3 Antibodies) with PTPN13 is mediated via the FERM domain of PTPN13 and via the N-terminus of SDCCAG3 (show SDCCAG3 Antibodies).

  5. Data indicate that Bcr-abl (show ABL1 Antibodies) increases PTPN13 promoter activity in an Icsbp (show IRF8 Antibodies)-dependent manner.

  6. Since PTPL1 catalytic activity is important for cell transformation, VCP (show vcp Antibodies) regulation by PTPL1 might be important for tumorigenesis.

  7. These findings demonstrate a key role for PTP-BL in 3T3-L1 and mouse embryo fibroblasts-derived adipocyte differentiation that is independent of its enzymatic activity.

  8. Structure, dynamics and binding characteristics of the second PDZ domain of PTP-BL

  9. With delayed kinetics, ephrinB ligands recruit the cytoplasmic PDZ domain containing protein (show USH1C Antibodies) tyrosine phosphatase PTP-BL and are dephosphorylated.

  10. FAP-1 has a role in binding to, and consequently inhibition of, Fas (show FAS Antibodies) export to the cell surface

PTPN13 Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.

Gene names and symbols associated with PTPN13

  • protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) (PTPN13) antibody
  • similar to protein tyrosine phosphatase type 1 (PTPN13) antibody
  • protein tyrosine phosphatase, non-receptor type 13 (ptpn13) antibody
  • protein tyrosine phosphatase, non-receptor type 13 (PTPN13) antibody
  • protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) (ptpn13) antibody
  • protein tyrosine phosphatase, non-receptor type 13 (Ptpn13) antibody
  • AI324989 antibody
  • FAP-1 antibody
  • hPTP1E antibody
  • PNP1 antibody
  • ptp antibody
  • PTP-BAS antibody
  • Ptp-bl antibody
  • PTP1E antibody
  • PTPL1 antibody
  • PTPLE antibody
  • ptpn13 antibody
  • Ptpri antibody
  • RIP antibody

Protein level used designations for PTPN13

fas-associated protein-tyrosine phosphatase 1 , hPTPE1 , protein-tyrosine phosphatase 1E , protein-tyrosine phosphatase PTPL1 , tyrosine-protein phosphatase non-receptor type 13 , protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) , protein tyrosine phosphatase, non-receptor type 13 , protein-tyrosine phosphatase BAS , tyrosine-protein phosphatase non-receptor type 13-like , PTP36 , protein tyrosine phosphatase DPZPTP , protein tyrosine phosphatase PTP-BL , protein-tyrosine phosphatase RIP , tyrosine phosphatase , protein Tyr phosphatase

GENE ID SPECIES
5783 Homo sapiens
422591 Gallus gallus
461359 Pan troglodytes
569591 Danio rerio
100144609 Felis catus
100455138 Pongo abelii
100477379 Ailuropoda melanoleuca
100521910 Sus scrofa
100540743 Meleagris gallopavo
100566747 Anolis carolinensis
100603082 Nomascus leucogenys
19249 Mus musculus
498331 Rattus norvegicus
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