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anti-Protein tyrosine Phosphatase, Receptor Type, A (PTPRA) Antibodies

The protein encoded by PTPRA is a member of the protein tyrosine phosphatase (PTP) family. Additionally we are shipping PTPRA Proteins (11) and PTPRA Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PTPRA 5786 P18433
PTPRA 19262 P18052
PTPRA 25167  
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Top anti-PTPRA Antibodies at antibodies-online.com

Showing 10 out of 93 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-PTPRA Antibody Titration: 0.2-1 ug/mlPositive Control: 293T cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated IF, IP, IHC, WB Western blot analysis of RPTPalpha on SW13 lysate. Lane 1: 1:500, lane 2: 1:1000, lane 3: 1:2000 dilution of RPTPalpha. U87 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HeLa cells treated with serum 20% 15', using PTPRA (Phospho-Tyr798) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB The anti-PTPalpha N-term Pab (ABIN392834) is used in Western blot to detect PTPalpha in mouse brain tissue lysate. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p) Anti-PTPRA antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1049270 dilution 10 ug/ml. Anti-PTPRA antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1049270 dilution 10 ug/ml. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p) Anti-PTPRA antibody IHC staining of human breast, epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1049271 dilution 4 ug/ml. Anti-PTPRA antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1049271 dilution 4 ug/ml. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti-PTPRA Polyclonal Antibody, unconjugated (ABIN754633) at 1:200 for 40 minutes at 37°C followed by labeling Rabbit Anti-Tubulin Beta, Cy3 conjugated 1:200, 40 minutes at 37° MCF-7 cell lysates probed with Anti-PTPRA Polyclonal Antibody, Unconjugated (ABIN754633) at 1:300 in 4˚C. Followed by conjugation to secondary antibody at 1:5000 90min in 37˚C. 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC (p) Anti-PTPRA antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1049272 concentration 4 ug/ml. Anti-PTPRA antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1049272 concentration 4 ug/ml. 50 μg Log in to see 8 to 10 Days
$451.00
Details

PTPRA Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-PTPRA Antibodies

  1. Human Polyclonal PTPRA Primary Antibody for EIA, WB - ABIN360736 : Kaplan, Morse, Huebner, Croce, Howk, Ravera, Ricca, Jaye, Schlessinger: Cloning of three human tyrosine phosphatases reveals a multigene family of receptor-linked protein-tyrosine-phosphatases expressed in brain. in Proceedings of the National Academy of Sciences of the United States of America 1990 (PubMed)
    Show all 5 references for ABIN360736

  2. Human Monoclonal PTPRA Primary Antibody for IF, IP - ABIN967914 : Sap, DEustachio, Givol, Schlessinger: Cloning and expression of a widely expressed receptor tyrosine phosphatase. in Proceedings of the National Academy of Sciences of the United States of America 1990 (PubMed)
    Show all 3 references for ABIN967914

  3. Chicken Polyclonal PTPRA Primary Antibody for WB - ABIN2782196 : Zheng, Resnick, Shalloway: Apoptosis of estrogen-receptor negative breast cancer and colon cancer cell lines by PTP alpha and src RNAi. in International journal of cancer. Journal international du cancer 2008 (PubMed)

More Antibodies against PTPRA Interaction Partners

Human Protein tyrosine Phosphatase, Receptor Type, A (PTPRA) interaction partners

  1. A receptor type-protein tyrosine phosphatase alpha-Src (show SRC Antibodies) family kinase-Rap1 (show RABGEF1 Antibodies) pathway was identified as responsible for recruiting myosin IIB (show MYH10 Antibodies) to the zonula adherens in epithelial cells and supporting contractile tension.

  2. no evidence was seen for the association of rare, missense mutations in the PTPRA gene with schizophrenia or autism spectrum disorders

  3. Data indicate that scaffold protein (show HOMER1 Antibodies) RACK1 (show GNB2L1 Antibodies) plays a role in IGF-1 (show IGF1 Antibodies)-mediated protein-tyrosine phosphatase alpha (PTPalpha) tyrosine phosphorylation in MCF-7 Cells.

  4. recruited to epithelial adherens junctions for cadherin-dependent cell adhesion and tissue architecture formation

  5. Results suggest that inhibition of PTPalpha can have a beneficial effect on HER2 (show ERBB2 Antibodies)-positive breast cancers, but that inhibition of additional targets is needed to block breast tumorigenesis.

  6. new role for PTPalpha in the regulation of motility of mammary epithelial cells in response to ErbB2 (show ERBB2 Antibodies) activation.

  7. results suggest that PTPalpha links activation of epidermal growth factor receptor (EGFR (show EGFR Antibodies)) signaling with Src (show SRC Antibodies) activation and may provide a novel therapeutic target for treatment of breast cancer.

  8. A single-nucleotide polymorphism (rs6138953) on the PTPRA gene in the 20p13 region was found to be associated with elevated fasting glucose level.

  9. The extracellular proteolytic processing is a novel mechanism for PTPalpha regulation.

  10. our results suggest that plasma PTPalpha and fibronectin (show FN1 Antibodies) may be associated with opisthorchiasis.

Mouse (Murine) Protein tyrosine Phosphatase, Receptor Type, A (PTPRA) interaction partners

  1. RPTPalpha mediates proinflammatory and proinvasive signaling in rheumatoid arthritis fibroblast-like synoviocytes (FLS), correlating with the promotion of disease in an FLS-dependent model of rheumatoid arthritis.

  2. Ptpra coordinates the regulation of the Fyn (show FYN Antibodies) signaling pathway in corpus striatum.

  3. PTPs (show PTS Antibodies) alpha and epsilon play distinct roles in osteoclasts.

  4. PTP (show SLC25A3 Antibodies)-alpha promotes profibrotic signaling pathways in fibroblasts through control of cellular responsiveness to TGF-beta (show TGFB1 Antibodies).

  5. The focal adhesion targeting domain of FAK (show PTK2 Antibodies) interacts with protein-tyrosine phosphatase-alpha to restrict IL1 (show IL1A Antibodies)-induced Ca2 (show CA2 Antibodies)+ release, ERK (show EPHB2 Antibodies) activation, and MMP-9 (show MMP9 Antibodies) expression.

  6. PTPalpha may be involved in the formation of axoglial junctions and ensheathment in small axons during myelination of the spinal cord.

  7. Findings indicate Grb2 (show GRB2 Antibodies) as a new FAK (show PTK2 Antibodies) activator and in coordinating PTPalpha tyrosine phosphorylation to enable downstream integrin signaling and migration.

  8. Results suggest that inhibition of PTPalpha can have a beneficial effect on HER2 (show ERBB2 Antibodies)-positive breast cancers, but that inhibition of additional targets is needed to block breast tumorigenesis.

  9. Inflammation-induced connective tissue degradation involving fibroblasts requires functionally active PTPalpha.

  10. study described a molecular complex of PTPalpha-BCAR3 (show BCAR3 Antibodies)-Cas (show CTNND1 Antibodies)-Src (show SRC Antibodies); this complex forms in response to PTPalpha Tyr789 phosphorylation and mediates Cas (show CTNND1 Antibodies) localization to focal adhesions and Cas (show CTNND1 Antibodies) downstream signaling to promote cell migration

Zebrafish Protein tyrosine Phosphatase, Receptor Type, A (PTPRA) interaction partners

  1. ptpra protein, zebrafish, signaling is essential for convergence and extension cell movements during gastrulation.

PTPRA Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported.

Gene names and symbols associated with PTPRA

  • protein tyrosine phosphatase, receptor type, A (PTPRA) antibody
  • protein tyrosine phosphatase, receptor type, A (ptpra) antibody
  • protein tyrosine phosphatase, receptor type, A (Ptpra) antibody
  • HEPTP antibody
  • HLPR antibody
  • HPTPA antibody
  • HPTPalpha antibody
  • LRP antibody
  • Ptpa antibody
  • ptpa-a antibody
  • Ptpalpha antibody
  • PTPRA antibody
  • PTPRL2 antibody
  • R-PTP-alpha antibody
  • RPTPA antibody
  • Rptpalpha antibody
  • RPTP[a] antibody
  • Rptra antibody
  • Rptralpha antibody
  • zf-RPTP[a] antibody

Protein level used designations for PTPRA

protein tyrosine phosphatase, receptor type, A , receptor-type tyrosine-protein phosphatase alpha-like , Leukocyte common antigen-related peptide (protein tyrosine phosphate) , PTPLCA-related phosphatase , PTPase-alpha , protein tyrosine phosphatase, receptor type, alpha polypeptide , protein-tyrosine phosphatase alpha , receptor-type tyrosine-protein phosphatase alpha , tyrosine phosphatase alpha , LCA-related phosphatase , PTPTY-28 , R-PTP-alpha , protein tyrosine phosphatase alpha , protein tyrosine phosphatase receptor type alpha , protein-tyrosine-phosphatase alpha

GENE ID SPECIES
100066880 Equus caballus
574364 Macaca mulatta
746684 Pan troglodytes
100017832 Monodelphis domestica
100158513 Xenopus (Silurana) tropicalis
100342875 Oryctolagus cuniculus
100373726 Saccoglossus kowalevskii
100404748 Callithrix jacchus
100449130 Pongo abelii
100464070 Ailuropoda melanoleuca
100605844 Nomascus leucogenys
5786 Homo sapiens
19262 Mus musculus
25167 Rattus norvegicus
140818 Danio rerio
394358 Xenopus laevis
396060 Gallus gallus
477176 Canis lupus familiaris
100138017 Bos taurus
100157496 Sus scrofa
Selected quality suppliers for anti-PTPRA (PTPRA) Antibodies
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