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Protein tyrosine Phosphatase, Receptor Type, B (PTPRB) ELISA Kits

The protein encoded by PTPRB is a member of the protein tyrosine phosphatase (PTP) family. Additionally we are shipping PTPRB Antibodies (18) and PTPRB Proteins (10) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
PTPRB 314843  
PTPRB 5787 P23467
PTPRB 19263 B2RU80
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Top PTPRB ELISA Kits at antibodies-online.com

Showing 10 out of 26 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human
96 Tests Log in to see 8 to 9 Days
$680.63
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Pig
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$770.00
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Chicken
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$770.00
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Rabbit
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$770.00
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Monkey
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$770.00
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Rat
96 Tests Log in to see 11 to 13 Days
$785.71
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Mouse
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$785.71
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Guinea Pig
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$801.43
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Goat
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$801.43
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Dog
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$801.43
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More ELISA Kits for PTPRB Interaction Partners

Human Protein tyrosine Phosphatase, Receptor Type, B (PTPRB) interaction partners

  1. Results provide evidence that PTPRB and PLCG1 (show PLCG1 ELISA Kits) mutations are driving events in a subset of secondary angiosarcomas.

  2. VE-PTP activates TIE2 (show TEK ELISA Kits) and stabilizes retinal and choroidal blood vessels

  3. these results suggest that the polarized redistribution of VE-PTP in response to shear stress plays an important role in the regulation of endothelial cells function by blood flow.

  4. The endothelial phosphatase PTPRB, a negative regulator of vascular growth factor tyrosine kinases, harbored predominantly truncating mutations in 10 of 39 angiosarcoma tumors.

  5. zinc(II) ions regulate receptor protein-tyrosine phosphatase (show PTPRT ELISA Kits) beta activity at picomolar concentrations.

  6. vascular endothelial protein tyrosine phosphatase contributes to endothelial morphogenesis. Silencing of VE-PTP expression was accompanied by increased VEGF receptor-2 tyrosine phosphorylation and activation of downstream signaling pathways.

  7. Suggest that VE-PTP, in cooperation with integrins, regulates the spreading and migration of endothelial cells during angiogenesis.

  8. The PTP1B (show PTPN1 ELISA Kits) has been observed over expressed in human breast cancer patients, suggesting its role in cell proliferation.

  9. the Ser127Gly polymorphism in PTPRB is associated with substance abuse vulnerability in three independent case-control samples, but was not associated with alcoholism in Japanese subjects

  10. These results reveal a novel role for HPTPbeta in modulating Ang-1 (show ANGPT1 ELISA Kits)-Tie2 (show TEK ELISA Kits) signaling and endothelial cell survival.

Mouse (Murine) Protein tyrosine Phosphatase, Receptor Type, B (PTPRB) interaction partners

  1. In the absence of Tie-2 (show TEK ELISA Kits), VE-PTP inhibition destabilizes endothelial barrier integrity in agreement with the VE-cadherin (show CDH5 ELISA Kits)-supportive effect of VE-PTP.

  2. The Lewis X (show FUT4 ELISA Kits) epitope is mainly expressed on phosphacan (show PTPRZ1 ELISA Kits)/receptor protein tyrosine phosphatase (show PTPRT ELISA Kits) beta (RPTPbeta) in the developing mouse brain.

  3. VE-PTP activates TIE2 (show TEK ELISA Kits) and stabilizes retinal and choroidal blood vessels

  4. We suggest that lymphocyte binding to vascular cell adhesion molecule 1 (show VCAM1 ELISA Kits) triggers a signaling process that enables a VE-PTP substrate to dissociate VE-PTP from VE-cadherin (show CDH5 ELISA Kits), thereby facilitating efficient transmigration.

  5. We conclude that the role of Tie2 (show TEK ELISA Kits) in maintenance of vascular quiescence involves VE-PTP-dependent dephosphorylation of VEGF receptor-2, and that VEGF receptor-2 activity regulates VE-cadherin (show CDH5 ELISA Kits) tyrosine phosphorylation, endothelial cell polarity

  6. IGFBP-2 (show IGFBP2 ELISA Kits) bound receptor protein tyrosine phosphatase (show PTPRT ELISA Kits) beta, which led to its dimerization and inactivation. Analysis of aortas obtained from IGFBP-2 (show IGFBP2 ELISA Kits)(-/-) mice showed that receptor protein tyrosine phosphatase (show PTPRT ELISA Kits) beta was activated.

  7. Suggest that VE-PTP, in cooperation with integrins, regulates the spreading and migration of endothelial cells during angiogenesis.

  8. Data show that vascular endothelial protein tyrosine phosphatase (VE-PTP) is a transmembrane binding partner of VE-cadherin (show CDH5 ELISA Kits) that reduces the tyrosine phosphorylation of VE-cadherin (show CDH5 ELISA Kits) and cell layer permeability.

  9. the activity of VE-PTP is not required for the initial formation of blood vessels, yet it is essential for their maintenance and remodeling.

  10. Vascular endothelial tyrosine phosphatase (VE-PTP)-null mice undergo vasculogenesis but die embryonically because of defects in angiogenesis.

PTPRB Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and one intracytoplasmic catalytic domain, thus belongs to receptor type PTP. The extracellular region of this PTP is composed of multiple fibronectin type_III repeats, which was shown to interact with neuronal receptor and cell adhesion molecules, such as contactin and tenascin C. This protein was also found to interact with sodium channels, and thus may regulate sodium channels by altering tyrosine phosphorylation status. The functions of the interaction partners of this protein implicate the roles of this PTP in cell adhesion, neurite growth, and neuronal differentiation. Alternate transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PTPRB

  • protein tyrosine phosphatase, receptor type, B (PTPRB) antibody
  • protein tyrosine phosphatase, receptor type, B (ptprb) antibody
  • protein tyrosine phosphatase, receptor type, B (Ptprb) antibody
  • protein tyrosine phosphatase, receptor type, B (LOC100350989) antibody
  • 3230402H02Rik antibody
  • C130094E24 antibody
  • HPTP-BETA antibody
  • HPTPB antibody
  • PTPB antibody
  • PTPRB antibody
  • Ptpz antibody
  • R-PTP-BETA antibody
  • Rptpb antibody
  • VE-PTP antibody
  • Veptp antibody

Protein level used designations for PTPRB

protein tyrosine phosphatase, receptor type, B , Receptor-type tyrosine-protein phosphatase beta , receptor-type tyrosine-protein phosphatase beta-like , receptor-type tyrosine-protein phosphatase beta , VE-PTP , protein tyrosine phosphatase, receptor type, beta polypeptide , vascular endothelial protein tyrosine phosphatase , R-PTP-beta , protein-tyrosine phosphatase beta

GENE ID SPECIES
718564 Macaca mulatta
100063580 Equus caballus
100380677 Salmo salar
100456419 Pongo abelii
100548729 Meleagris gallopavo
100582561 Nomascus leucogenys
314843 Rattus norvegicus
5787 Homo sapiens
19263 Mus musculus
100350989 Oryctolagus cuniculus
100720273 Cavia porcellus
100156181 Sus scrofa
481162 Canis lupus familiaris
505696 Bos taurus
417853 Gallus gallus
101121760 Ovis aries
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