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Protein tyrosine Phosphatase, Receptor Type, R Proteins (PTPRR)

The protein encoded by PTPRR is a member of the protein tyrosine phosphatase (PTP) family. Additionally we are shipping Protein tyrosine Phosphatase, Receptor Type, R Antibodies (88) and Protein tyrosine Phosphatase, Receptor Type, R Kits (20) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PTPRR 5801 Q15256
PTPRR 19279 Q62132
PTPRR 94202 O08617
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Top Protein tyrosine Phosphatase, Receptor Type, R Proteins at antibodies-online.com

Showing 8 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,489.67
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PTPRR Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,
Mouse (Murine) ,
,
Rat (Rattus)

Top referenced Protein tyrosine Phosphatase, Receptor Type, R Proteins

  1. Human PTPRR Protein expressed in Wheat germ - ABIN1316885 : Xu, Chatterjee, Baguley, Brouillette, Kurup, Ghosh, Kanyo, Zhang, Seyb, Ononenyi, Foscue, Anderson, Gresack, Cuny, Glicksman, Greengard, Lam, Tautz, Nairn, Ellman, Lombroso: Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease. in PLoS biology 2014 (PubMed)

More Proteins for Protein tyrosine Phosphatase, Receptor Type, R (PTPRR) Interaction Partners

Human Protein tyrosine Phosphatase, Receptor Type, R (PTPRR) interaction partners

  1. Results show that PTPRR is an early and direct target of the androgen receptor which negatively regulates the RAS/ERK1/2 pathway suggesting that its loss in prostate cancer cells is one factor that might contribute to activation of the RAS/ERK1/2 pathway.

  2. High expression of PTP receptors R and Z1 was observed in all examined cases of colorectal carcinoma, adenoma and normal colon tissue in this study.

  3. The methylation index of PTPRR recovered from scrapings of uterine cervix adenocarcinomas is significantly higher than in normal controls.

  4. 3 genes identified by association study and supported by ocular expression and/or replication, UHRF1BP1L, PTPRR, and PPFIA2, are novel candidates for myopic development within the MYP3 locus that should be further studied.

  5. Methylation of the PTPRR promoter has an important role in the metastasis and may be a biomarker of invasive cervical cancer

  6. the protein tyrosine phosphatase receptor type R gene may play a role in conferring risk of major depressive disorder in females

  7. expression of the PTPRR-1 isoform was inactivated in colorectal cancer cells as a result of de novo CpG island methylation and enrichment of transcription-repressive histone-tail marks, mainly H3K27me3

  8. determined high-resolution structures of all of the human family members of Mitogen-Activated Protein Kinase (show MAPK1 Proteins)-specific protein tyrosine phosphatases

Mouse (Murine) Protein tyrosine Phosphatase, Receptor Type, R (PTPRR) interaction partners

  1. These findings indicate an important role for PTPRR in maintaining low basal mitogen-activated protein kinase (show MAPK1 Proteins) activity in Purkinje cells.

  2. The data of this study disclosed a distinct role for PTPRR in recognition memory and exploration of a new environment.

  3. Results support the suggested link between PTPRR isoforms and cerebellar calcium ion homeostasis, and suggest an additional role in the process of cell-cell adhesion

  4. The ERK2 (show MAPK1 Proteins) docking groove is more restrictive and selective for its tyrosine phosphatase inactivators than for MEK1 (show MAP2K1 Proteins)/2 and indicate that distinct ERK2 (show MAPK1 Proteins) residues modulate the docking interactions with activating and inactivating effectors.

  5. PTPBR7, was subject to N-terminal proteolytic processing, in between amino acid position 136 and 137, resulting in an additional, 65-kDa transmembrane PTPRR isoform.

  6. Ptprr-/- mice displayed ataxia (show USP14 Proteins) characterized by defects in fine motor coordination and balance skills.

  7. PTP-SL, like PTPBR7, is a single membrane-spanning receptor-type protein tyrosine phosphatases.

Protein tyrosine Phosphatase, Receptor Type, R (PTPRR) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12.

Gene names and symbols associated with PTPRR

  • protein tyrosine phosphatase, receptor type, R (PTPRR)
  • protein tyrosine phosphatase, receptor type, R (ptprr)
  • protein tyrosine phosphatase, receptor type, R (Ptprr)
  • protein tyrosine phosphatase, receptor type, r (ptprr)
  • protein tyrosine phosphatase, receptor type, R (PTPRQ)
  • EC-PTP protein
  • Gmcp1 protein
  • mPTP213 protein
  • Pcptp1 protein
  • PTP-SL protein
  • PTPBR7 protein
  • PTPRQ protein
  • PTPRR protein
  • RPTPRR protein

Protein level used designations for PTPRR

protein tyrosine phosphatase, receptor type, R , protein tyrosine phosphatase, receptor type, Q , Receptor-type tyrosine-protein phosphatase R , receptor-type tyrosine-protein phosphatase R , receptor-type tyrosine-protein phosphatase R-like , Ch-1 PTPase , NC-PTPCOM1 , R-PTP-R , ch-1PTPase , protein tyrosine phosphatase Cr1PTPase , protein-tyrosine phosphatase NC-PTPCOM1 , protein-tyrosine phosphatase PCPTP1 , STEP-like PTPase , phosphotyrosine phosphatase 13 , protein-tyrosine-phosphatase SL , protein-tyrosine-phosphatase-SL , PC12-PTP1 , protein tyrosine phosphatase PCPTP1 , tyrosine phosphatase CBPTP

GENE ID SPECIES
452076 Pan troglodytes
697153 Macaca mulatta
718582 Macaca mulatta
100015968 Monodelphis domestica
100063646 Equus caballus
100125100 Xenopus (Silurana) tropicalis
100172750 Pongo abelii
100226660 Taeniopygia guttata
100398974 Callithrix jacchus
100474182 Ailuropoda melanoleuca
100549190 Meleagris gallopavo
100567785 Anolis carolinensis
100583678 Nomascus leucogenys
100605062 Nomascus leucogenys
5801 Homo sapiens
398636 Xenopus laevis
771985 Gallus gallus
481163 Canis lupus familiaris
536337 Bos taurus
19279 Mus musculus
94202 Rattus norvegicus
100526652 Danio rerio
100351238 Oryctolagus cuniculus
100715069 Cavia porcellus
100154962 Sus scrofa
482581 Canis lupus familiaris
101121162 Ovis aries
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