Protein-O-Mannosyltransferase 2 (POMT2) ELISA Kits

The protein encoded by POMT2 is an O-mannosyltransferase that requires interaction with the product of the POMT1 gene for enzymatic function. Additionally we are shipping POMT2 Antibodies (41) and POMT2 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human POMT2 POMT2 29954 Q9UKY4
Anti-Mouse POMT2 POMT2 217734 Q8BGQ4
Anti-Rat POMT2 POMT2 688673  
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More ELISA Kits for POMT2 Interaction Partners

Fruit Fly (Drosophila melanogaster) Protein-O-Mannosyltransferase 2 (POMT2) interaction partners

  1. Drosophila POMT1 (show POMT1 ELISA Kits) and POMT2 function as a protein O-mannosyltransferase in association with each other to generate and maintain normal muscle development.

  2. establish a central role for Dystroglycan (Dg) in maintaining integrity in Drosophila larval muscles and demonstrate the importance of glycosylation to Dg function in Drosophila

Zebrafish Protein-O-Mannosyltransferase 2 (POMT2) interaction partners

Human Protein-O-Mannosyltransferase 2 (POMT2) interaction partners

  1. O-mannosylation of cadherins and protocadherins does not require POMT1 (show POMT1 ELISA Kits) and/or POMT2 in contrast to alpha-dystroglycan, and moreover, the O-Man glycans on cadherins are not elongated.

  2. Our report is the first to document an association between POMT2 mutations and aortopathy with concomitant depressed left ventricular systolic function.

  3. the effects of replacing Arg(64), Glu (show DCTN1 ELISA Kits)(78) and Arg(138)residues in human POMT1 (show POMT1 ELISA Kits) and POMT2 with Ala on complex formation and enzymatic activity were studied.

  4. the function of the gene products is only known for POMT1 (show POMT1 ELISA Kits), POMT2, and POMGnT1 (show POMGNT1 ELISA Kits), all responsible for the O-mannosylglycan biosynthesis

  5. the N-glycosylation of POMT1 (show POMT1 ELISA Kits) and POMT2 is required for maintaining the conformation as well as the activity of the POMT1 (show POMT1 ELISA Kits)-POMT2 complex.

  6. active enzyme complex of POMT1 (show POMT1 ELISA Kits) and POMT2 suggests that the regulation of protein O-mannosylation is complex and appears to be required for normal structure and function of alpha-dystroglycan in muscle and brain

  7. POMT2 mutations cause alpha-dystroglycan hypoglycosylation and Walker-Warburg syndrome [case reports]

  8. Several mutations were found in the Protein O-Mannosyltransferase 1 (show POMT1 ELISA Kits) and 2 (POMT1 (show POMT1 ELISA Kits) and POMT2) genes, and one mutation was found in each of the fukutin (show FKTN ELISA Kits) and fukutin-related protein (FKRP (show FKRP ELISA Kits)) genes.

  9. Our results broaden the clinical spectrum associated with POMT2 mutations, which should be considered in patients with CMD (show ACAN ELISA Kits) associated with microcephaly, and severe mental retardation with or without ocular involvement.

  10. identified a POMT2 homozygous missense mutation in a girl with a mild limb-girdle muscular dystrophy (LGMD) phenotype

Mouse (Murine) Protein-O-Mannosyltransferase 2 (POMT2) interaction partners

  1. Data show that POMT2 deletion in the meninges did not disrupt the development of the neocortex, and suggest that normal brain development requires protein O-mannosylation activity in neural tissue but not the meninges.

  2. testis POMT2 is highly conserved among mammals, including humans, suggesting a crucial function that is distinct from somatic POMT2

POMT2 Antigen Profile

Antigen Summary

The protein encoded by this gene is an O-mannosyltransferase that requires interaction with the product of the POMT1 gene for enzymatic function. The encoded protein is found in the membrane of the endoplasmic reticulum. Defects in this gene are a cause of Walker-Warburg syndrome (WWS).

Gene names and symbols associated with POMT2

  • Protein O-mannosyltransferase 2 (tw) antibody
  • protein-O-mannosyltransferase 2 (POMT2) antibody
  • protein-O-mannosyltransferase 2 (pomt2) antibody
  • protein-O-mannosyltransferase 2 (Pomt2) antibody
  • A830009D15Rik antibody
  • AW046274 antibody
  • CG12311 antibody
  • Dmel\\CG12311 antibody
  • DmPOMT2 antibody
  • dPOMT2 antibody
  • EG:34F3.7 antibody
  • im:7153045 antibody
  • LGMD2N antibody
  • MDDGA2 antibody
  • MDDGB2 antibody
  • MDDGC2 antibody
  • Pomt2 antibody
  • zgc:158749 antibody
  • zPOMT2 antibody

Protein level used designations for POMT2

CG12311-PA , CG12311-PB , protein O-mannosyltransferase 2 , tricky-dickey , tw-PA , tw-PB , twisted , putative protein O-mannosyltransferase , protein-O-mannosyltransferase 2 , protein O-mannosyl-transferase 2 , protein O-mannosyl-transferase 2-like , dolichyl-phosphate-mannose--protein mannosyltransferase 2

31024 Drosophila melanogaster
453067 Pan troglodytes
480400 Canis lupus familiaris
705604 Macaca mulatta
100022191 Monodelphis domestica
100155173 Sus scrofa
100400916 Callithrix jacchus
100437813 Pongo abelii
100490100 Xenopus (Silurana) tropicalis
100566915 Anolis carolinensis
563878 Danio rerio
423373 Gallus gallus
29954 Homo sapiens
537054 Bos taurus
217734 Mus musculus
688673 Rattus norvegicus
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