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Proteoglycan 4 (Megakaryocyte Stimulating Factor, Articular Superficial Zone Protein) (PRG4) ELISA Kits

Plays a role in boundary lubrication within articulating joints. Additionally we are shipping Proteoglycan 4 (Megakaryocyte Stimulating Factor, Articular Superficial Zone Protein) Antibodies (19) and Proteoglycan 4 (Megakaryocyte Stimulating Factor, Articular Superficial Zone Protein) Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
PRG4 64748 Q96GM1
Anti-Rat PRG4 PRG4 289104  
PRG4 96875 Q9JM99
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Top Proteoglycan 4 (Megakaryocyte Stimulating Factor, Articular Superficial Zone Protein) ELISA Kits at antibodies-online.com

Showing 2 out of 5 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.54 ng/mL 62.5-4000 pg/mL 96 Tests Log in to see 9 to 11 Days
$736.84
Details
Mouse 3.9 ng/ml 15.6-1000 ng/mL   96 Tests Log in to see 9 to 11 Days
$910.56
Details

Top referenced Proteoglycan 4 (Megakaryocyte Stimulating Factor, Articular Superficial Zone Protein) ELISA Kits

  1. Human PRG4 ELISA Kit for Sandwich ELISA - ABIN421836 : Roffi, Filardo, Assirelli, Cavallo, Cenacchi, Facchini, Grigolo, Kon, Mariani, Pratelli, Pulsatelli, Marcacci: Does platelet-rich plasma freeze-thawing influence growth factor release and their effects on chondrocytes and synoviocytes? in BioMed research international 2014 (PubMed)

More ELISA Kits for Proteoglycan 4 (Megakaryocyte Stimulating Factor, Articular Superficial Zone Protein) Interaction Partners

Mouse (Murine) Proteoglycan 4 (Megakaryocyte Stimulating Factor, Articular Superficial Zone Protein) (PRG4) interaction partners

  1. Prg4 is needed for TMJ disc integrity and function and its absence leads to ectopic chondrogenesis and cartilage formation in conjunction with abnormal BMP signaling.

  2. Discs from Prg4 null mice had a significantly smaller mean transverse disc area, with a significantly larger proportion of this area occupied by the nucleus pulposus.

  3. PRG4 is a novel putative ligand for CD44 (show CD44 ELISA Kits) and may control synoviocyte overgrowth in inflammatory arthropathies via a CD44 (show CD44 ELISA Kits)-mediated mechanism.

  4. Prg4-expressing cells at the embryonic joint surface serve as a progenitor population for deeper layers of mature articular cartilage. Prg4 is expressed by superficial chondrocytes in young mice but in deeper regions of articular cartilage in older mice.

  5. findings confirm the importance of lubricin in intrasynovial tendon lubrication.

  6. mechanical motion may induce Prg4 expression in the superficial zone of articular cartilage

  7. changes in synovial fluid proteins and PRG4 concentrations upon joint loading are mediated by cells within the joint, and that these changes may be used as quantitative indicators for the intensity and duration of acute joint loading

  8. Lubricin is transcribed, translated, and expressed by ocular surface epithelia. Lubricin presence significantly reduces friction between the cornea and conjunctiva and its deficiency may play a role in promoting corneal damage.

  9. lubricin has roles in boundary lubrication, and cell survival

  10. Blunted PTH (show PTH ELISA Kits) anabolic responses in adult Prg4 mutant mice are associated with altered biomechanical impact secondary to joint failure.

Proteoglycan 4 (Megakaryocyte Stimulating Factor, Articular Superficial Zone Protein) (PRG4) Antigen Profile

Antigen Summary

Plays a role in boundary lubrication within articulating joints. Prevents protein deposition onto cartilage from synovial fluid by controlling adhesion-dependent synovial growth and inhibiting the adhesion of synovial cells to the cartilage surface.

Gene names and symbols associated with PRG4

  • lipid phosphate phosphatase-related protein type 2 (LPPR2) antibody
  • proteoglycan 4 (Prg4) antibody
  • proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein) (Prg4) antibody
  • CACP antibody
  • DOL54 antibody
  • JCAP antibody
  • lubricin antibody
  • MSF antibody
  • PRG4 antibody
  • SZP antibody

Protein level used designations for PRG4

PRG-4 , plasticity related gene 4 , plasticity-related gene 4 protein , proteoglycan 4, (megakaryocyte stimulating factor, articular superficial zone protein, camptodactyly, arthropathy, coxa vara, pericarditis syndrome) , megakaryocyte-stimulating factor , proteoglycan 3 , proteoglycan 4 , superficial zone proteoglycan

GENE ID SPECIES
64748 Homo sapiens
289104 Rattus norvegicus
96875 Mus musculus
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