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human homolog plays a role in anti-apoptosis. Additionally we are shipping PTMA Antibodies (89) and PTMA Proteins (16) and many more products for this protein.
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These results demonstrate the clinical relevance of prothymosin alpha in regulating acetylation events during the pathogenesis of emphysema.
Only neurons possess the specific mechanisms required to release prothymosin-alpha following cerebral ischemic stress in vivo.
Regional distribution and cell type-specific subcellular localization of Prothymosin alpha in brain.
Thymosin alpha-1 could relieve radiation-induced acute and late pulmonary injuries.
observations suggest that Talpha1 can positively modulate the haematopoietic functions of normal murine bone marrow cells, in addition to its myelorestorative role in tumour-bearing mice showing suppressed myelopoiesis [thymosin alpha-1]
thymosin alpha 1, a naturally occurring thymic peptide, induces functional maturation and interleukin-12 production by fungus-pulsed DCs through the p38 mitogen-activated protein kinase (show MAPK14 ELISA Kits)/nuclear factor (NF)-kappaB (show NFKB1 ELISA Kits)-dependent pathway.
ProT (show SLC6A7 ELISA Kits) overexpression in the kidneys of homozygous transgenic mice induced a PKD (show PRKD1 ELISA Kits) phenotype, which included polycystic kidneys, elevated blood urea nitrogen (BUN), and lethality at about 10 days of age.
Keap1 (show KEAP1 ELISA Kits)-bound prothymosin alpha peptide possesses a hairpin conformation and binds to cytoplasmic repressor Keap1 (show KEAP1 ELISA Kits) at the bottom region of the beta-propeller domain; complex formation occurs as a consequence of their complementary electrostatic interactions.
The systemic administration of Prothymosin alpha switches ischemia-induced necrosis to apoptosis, which in turn is inhibited by neurotrophic factors upregulated by Prothymosin alpha and ischemia.
prothymosin-alpha-mediated nuclear import of INrf2 (show KEAP1 ELISA Kits)/Cul3 (show CUL3 ELISA Kits) Rbx1 complex leads to ubiquitination and degradation of Nrf2 (show NFE2L2 ELISA Kits) inside the nucleus presumably to regulate nuclear level of Nrf2 (show NFE2L2 ELISA Kits) and rapidly switch off the activation of Nrf2 (show NFE2L2 ELISA Kits) downstream gene expression.
PTMA is a potential novel therapeutic target for type 2 diabetes
disease-free survival and overall survival rates were significantly lower among colorectal cancer patients with PTMA- and TP53 (show TP53 ELISA Kits)-positive tumors
Data suggest that KEAP1 (kelch-like ECH-associated protein 1 (show KEAP1 ELISA Kits)) mutations (as those observed in lung cancer patients) affect conformation/folding/stability of KEAP1 (show KEAP1 ELISA Kits) and binding affinity for ligands PTMA and NRF2 (nuclear factor erythroid 2-like 2 (show NFE2L2 ELISA Kits)).
Data suggest that plasma thymosin-alpha1 (TA1 (show TAAR1 ELISA Kits)) and prothymosin-alpha (PTMA) level may be a biomarker for differentiating between renal cell carcinoma (RCC (show XRCC1 ELISA Kits)) and urothelial carcinoma.
prothymosin-alpha expression is a determinant of disease progression in superficial bladder cancer
PTalpha (show PTCRA ELISA Kits) offers cardioprotection against ischemic injury by an Akt (show AKT1 ELISA Kits)-dependent mechanism.
The PTMA is one of miR-1 target genes which involve in miR-1 inducing apoptosis.
Findings suggest that the binding of prothymosin alpha (ProTalpha) and Neh2 (show NEIL2 ELISA Kits) to Keap1 (show KEAP1 ELISA Kits) occurs synergistically via preformed structural elements.
Nuclear PTMA may serve as prognostic marker in head and neck squamous cell carcinoma to determine the subset of patients that are likely to show recurrence of the disease.
human homolog plays a role in anti-apoptosis
, prothymosin, alpha (gene sequence 28)
, prothymosin alpha
, gene sequence 28
, prothymosin alpha protein