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PCDH17 belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. Additionally we are shipping PCDH17 Proteins (4) and many more products for this protein.
Showing 10 out of 51 products:
Human Polyclonal PCDH17 Primary Antibody for EIA, WB - ABIN954028
Biswas, Jontes: Cloning and characterization of zebrafish protocadherin-17. in Development genes and evolution 2009
Show all 4 references for ABIN954028
Cow (Bovine) Polyclonal PCDH17 Primary Antibody for WB - ABIN2785751
Szafranski, Schindler, Taudien, Hiller, Huse, Jahn, Schreiber, Backofen, Platzer: Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns. in Genome biology 2008
PCDH17 methylation in serum is a frequent event in early-stage prostate cancer, and it is an independent predictor of BCR (show BCR Antibodies) after radical prostatectomy
PCDH17 methylation occurred more frequently and was associated with malignant clinicopathological characteristics and poor prognosis in clear cell renal cell carcinoma (show MOK Antibodies) patients
PCDH17 promoter methylation is closely associated with bladder cancer malignancy and may be used as an independent predictor of clinical outcomes in patients with bladder cancer.
PCDH17 promoter methylation was significantly associated with malignant behaviour and poor prognosis of bladder cancer
This study demonistrated that critical role for PCDH17 in the synaptic development of specific corticobasal ganglia circuits and suggest the involvement of PCDH17 in such circuits in depressive behaviors.
PCDH17 acts as a tumour suppressor, exerting its anti-proliferative activity through inducing apoptosis and autophagy, and is frequently silenced in gastric and colorectal cancers.
Our study clearly demonstrates that PCDH17 is transcriptionally downregulated in gastric cancer due to aberrant promoter CpG island methylation
statistical significant downregulation of PCDH17/PCH68 and PTPRD (show PTPRD Antibodies) was observed
results suggest that silencing of PCDH17 expression through hypermethylation of the promoter or other mechanisms leads to loss of its tumour-suppressive activity, which may be a factor in the carcinogenesis of a subgroup of ESCCs
Azoospermic testis showed down-regulation of CDH18 (show CDH18 Antibodies) and PCDH17.
Pcdh17 recruits the WAVE complex, Lamellipodin (show RAPH1 Antibodies), and Ena/VASP (show VASP Antibodies) to cell-cell contacts, converting these sites into motile structures.
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein contains six extracellular cadherin domains, a transmembrane domain, and a cytoplasmic tail differing from those of the classical cadherins. The encoded protein may play a role in the establishment and function of specific cell-cell connections in the brain.