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anti-Protoporphyrinogen Oxidase (PPOX) Antibodies

PPOX encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Additionally we are shipping Protoporphyrinogen Oxidase Kits (12) and Protoporphyrinogen Oxidase Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PPOX 15171 O55241
PPOX 5498 P50336
PPOX 289219  
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Top anti-Protoporphyrinogen Oxidase Antibodies at antibodies-online.com

Showing 10 out of 56 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PPOX Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HT1080 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: A549 B: HCT116 10% SDS PAGE antibody diluted at 1:2000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Mouse Un-conjugated IHC (p), RNAi, ELISA, WB Immunoperoxidase of monoclonal antibody to PPOX on formalin-fixed paraffin-embedded human lung, adenosquamous cell carcinoma. [antibody concentration 3 ug/ml] Western blot analysis of PPOX over-expressed 293 cell line, cotransfected with PPOX Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with PPOX monoclonal antibody (M01), clone 2F10. GAPDH ( 36.1 kDa ) used as specificity and loading control. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated WB Western blot analysis of PPOX over-expressed 293 cell line, cotransfected with PPOX Validated Chimera RNAi used as specificity and loading control. Western Blot analysis of PPOX expression in transfected 293T cell line by PPOX monoclonal antibody (M01), clone 2F10. Lane 1: PPOX transfected lysate(50.8 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB PPOX antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB 100 μg Log in to see 8 to 10 Days
$537.17
Details
Human Mouse Un-conjugated ELISA, WB Western Blot analysis of PPOX expression in transfected 293T cell line by PPOX monoclonal antibody (M04A), clone 2B5.Lane 1: PPOX transfected lysate (Predicted MW: 50.8 KDa).Lane 2: Non-transfected lysate. Western Blot detection against Immunogen (36.74 KDa) . 200 μL Log in to see 9 Days
$430.00
Details

PPOX Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,


Human , , ,
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Rat (Rattus) ,


Top referenced anti-Protoporphyrinogen Oxidase Antibodies

  1. Human Monoclonal PPOX Primary Antibody for IHC (p), RNAi - ABIN562343 : Crooks, Ghosh, Haller, Tong, Rouault: Posttranslational stability of the heme biosynthetic enzyme ferrochelatase is dependent on iron availability and intact iron-sulfur cluster assembly machinery. in Blood 2010 (PubMed)
    Show all 3 references for ABIN562343

  2. Cow (Bovine) Polyclonal PPOX Primary Antibody for WB - ABIN2786509 : de Vooght, van Wijk, van Solinge: GATA-1 binding sites in exon 1 direct erythroid-specific transcription of PPOX. in Gene 2008 (PubMed)

More Antibodies against Protoporphyrinogen Oxidase Interaction Partners

Mouse (Murine) Protoporphyrinogen Oxidase (PPOX) interaction partners

  1. Awake dynamics and brain-wide direct inputs of hypothalamic MCH (show PMCH Antibodies) and orexin/hypocretin (show OX Antibodies) networks have been discovered.

  2. Histamine Transmission Modulates the Phenotype of Murine Narcolepsy Caused by Orexin (show OX Antibodies) Neuron Deficiency

  3. observation that inhibition of the Orexin (show OX Antibodies)-1 receptor signaling blunted binge-like Ethanol, and saccharin drinking suggests that reward-related Orexin (show OX Antibodies) circuits participate in the consumption of salient reinforcers regardless of calories.

  4. Results suggest that exercise produces antidepressant effects via suppression of Hcrt (show OX Antibodies)/Orx and melanin-concentrating hormone (show PMCH Antibodies) neural systems in the basolateral amygdala

  5. Hcrt (show OX Antibodies) neuronal activity and Hcrt (show OX Antibodies)-mediated stress responses were inhibited by the satiety hormone leptin (show LEP Antibodies).

  6. This study demonstrated that the GABAergic input property of orexin (show OX Antibodies) neurons responds rapidly to sleep deprivation.

  7. sleep deprivation or increasing wakefulness by rescue of orexinergic neurons in APP (show APP Antibodies)/PS1 (show PSEN1 Antibodies) mice lacking orexin (show OX Antibodies) increased the amount of amyloid beta pathology in the brain.

  8. orexin (show OX Antibodies) activates the mTOR (show FRAP1 Antibodies) pathway, a central regulator of cell growth and metabolism, in the mouse brain and cell lines that express GPCRs, OX1R (show HCRTR1 Antibodies), or OX2R (show CD200R1 Antibodies)

  9. This study demonistrated that absence of the Hcrt (show OX Antibodies) peptide has gender-specific effects. In contrast, Hcrt (show OX Antibodies)-ataxin mice and human narcoleptics, with loss of the whole Hcrt (show OX Antibodies) cell, show weight gain in both sexes.

  10. These results suggest that orexin (show OX Antibodies) neuronal activity plays a crucial role in the maintenance of wakefulness especially in the active phase in mice.

Human Protoporphyrinogen Oxidase (PPOX) interaction partners

  1. GAPDH (show GAPDH Antibodies) and protoporphyrinogen oxidase were shown to have higher expression in faster growing cell lines and primary tumors. Pharmacologic inhibition of GAPDH (show GAPDH Antibodies) or PPOX (show OX Antibodies) reduced the growth of colon cancer cells in vitro

  2. Variegate porphyria is the result of decreased protoporphyrinogen oxidase activity. Diet supplementation with vitamins E and C restores PPOX (show OX Antibodies) gene expression in lymphocytes of variegate porphyria patients.

  3. in the hepatic cancer tissue of two acute porphyria patients, somatic second-hit mutations result in nearly complete inactivation of PPOX (show OX Antibodies) and HMBS (show HMBS Antibodies)

  4. The c.851G>T and the c.1013C>G of PPOX (show OX Antibodies) gene were found in two and four unrelated families respectively. 1 experienced only photosensitivity, 1 only neurological symptoms and the 2 both clinical manifestations.

  5. The mutation 1082-1083insC(1 base pair insertion at position 1082) in exon 10 of the PPOX (show OX Antibodies) gene was prevalent in the Swiss population.

  6. findings emphasize the usefulness of MLPA analysis as a complement to PPOX (show OX Antibodies) gene sequencing analysis for comprehensive genetic diagnostics in patients with variegate prophyria

  7. Information required for targeting to the mitochondria is contained within the first 250 amino acid residues of human PPOX (show OX Antibodies).

  8. Modulation of penetrance by the wild-type allele in dominantly inherited erythrohepatic and acute hepatic porphyrias was studied using PPOX (show OX Antibodies).

  9. Protoporphyrinogen oxidase targeting mechanism to the mitochondrion.

  10. Mutation in protoporphyrinogen oxidase is associated with variegate porphyria

Arabidopsis thaliana Protoporphyrinogen Oxidase (PPOX) interaction partners

  1. The tetrapyrrole biosynthetic enzyme PPO1 is required for plastid RNA editing.

Protoporphyrinogen Oxidase (PPOX) Antigen Profile

Protein Summary

This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.

Gene names and symbols associated with PPOX

  • Protoporphyrinogen oxidase (Ppox) antibody
  • protoporphyrinogen oxidase (ppox) antibody
  • protoporphyrinogen oxidase (hemY) antibody
  • protoporphyrinogen oxidase (Mrub_1406) antibody
  • protoporphyrinogen oxidase (Mesil_2992) antibody
  • protoporphyrinogen oxidase (Trad_0583) antibody
  • protoporphyrinogen oxidase (Calni_0746) antibody
  • protoporphyrinogen oxidase (Ocepr_1049) antibody
  • protoporphyrinogen oxidase (Tmar_0766) antibody
  • protoporphyrinogen oxidase (Intca_1907) antibody
  • protoporphyrinogen oxidase (Despr_0642) antibody
  • protoporphyrinogen oxidase (Plabr_2407) antibody
  • protoporphyrinogen oxidase (Deipr_2130) antibody
  • protoporphyrinogen oxidase (Hipma_0622) antibody
  • hypocretin (Hcrt) antibody
  • protoporphyrinogen oxidase (Ppox) antibody
  • protoporphyrinogen oxidase (PPOX) antibody
  • BcDNA:LD41392 antibody
  • CG5796 antibody
  • Dmel\\CG5796 antibody
  • ESTS:9F2T antibody
  • hemG antibody
  • HEMG1 antibody
  • Ppo antibody
  • PPO1 antibody
  • PPOX antibody
  • PROTOPORPHYRINOGEN OXIDASE antibody
  • TC0121 antibody
  • V290M antibody
  • VP antibody
  • zgc:123252 antibody

Protein level used designations for PPOX

protoporphyrinogen oxidase , CG5796-PA , Ppox-PA , protoporphyrinogen-oxidase , mno , montalcino , ppo , orexin , orexin A , orexin B , prepro-orexin , protoporhyrinogen oxidase

GENE ID SPECIES
42939 Drosophila melanogaster
664750 Danio rerio
887711 Mycobacterium tuberculosis H37Rv
894184 Bacillus halodurans C-125
910131 Mycobacterium leprae TN
1017310 Oceanobacillus iheyensis HTE831
1121814 Staphylococcus aureus subsp. aureus Mu50
1245655 Chlamydia muridarum Nigg
2860707 Staphylococcus aureus subsp. aureus MRSA252
3204574 Bacillus clausii KSM-K16
3958489 Chlamydophila felis Fe/C-56
5331016 Staphylococcus aureus subsp. aureus str. Newman
5560658 Staphylococcus aureus subsp. aureus Mu3
6226299 Mycobacterium marinum M
7324674 Mycobacterium leprae Br4923
7550597 Staphylococcus carnosus subsp. carnosus TM300
8767366 Bacillus pseudofirmus OF4
8879503 Meiothermus ruber DSM 1279
9252515 Meiothermus silvanus DSM 9946
9279560 Truepera radiovictrix DSM 17093
10008757 Calditerrivibrio nitroreducens DSM 19672
10015901 Oceanithermus profundus DSM 14977
10081140 Thermaerobacter marianensis DSM 12885
10084727 Intrasporangium calvum DSM 43043
10173352 Desulfobulbus propionicus DSM 2032
10239818 Planctomyces brasiliensis DSM 5305
10265450 Deinococcus proteolyticus MRP
10391952 Hippea maritima DSM 10411
15171 Mus musculus
19044 Mus musculus
5498 Homo sapiens
478980 Canis lupus familiaris
515770 Bos taurus
289219 Rattus norvegicus
100153636 Sus scrofa
100340158 Oryctolagus cuniculus
827991 Arabidopsis thaliana
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