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Pterin-4 alpha-Carbinolamine Dehydratase/dimerization Cofactor of Hepatocyte Nuclear Factor 1 alpha (PCBD1) ELISA Kits

PCBD1 encodes pterin-4 alpha-carbinolamine dehydratase, an enzyme involved in phenylalanine hydroxylation. Additionally we are shipping PCBD1 Antibodies (51) and PCBD1 Proteins (19) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse PCBD1 PCBD1 13180 P61458
Anti-Human PCBD1 PCBD1 5092 P61457
Anti-Rat PCBD1 PCBD1 29700 P61459
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More ELISA Kits for PCBD1 Interaction Partners

Mouse (Murine) Pterin-4 alpha-Carbinolamine Dehydratase/dimerization Cofactor of Hepatocyte Nuclear Factor 1 alpha (PCBD1) interaction partners

  1. DCoH acts as a cofactor for HNF1 that stabilizes the dimeric HNF1 complex.

  2. HNF1alpha (show HNF1A ELISA Kits) binding kinetics may distinguish regulation by DCoH2 (show PCBD2 ELISA Kits), under thermodynamic control, from regulation by DCoH, under kinetic control

Human Pterin-4 alpha-Carbinolamine Dehydratase/dimerization Cofactor of Hepatocyte Nuclear Factor 1 alpha (PCBD1) interaction partners

  1. We provide the first genetic evidence that PCBD1 mutations can cause early-onset nonautoimmune diabetes with features similar to dominantly inherited HNF1A (show HNF1A ELISA Kits)-diabetes.

  2. Coactivator of the HNFB1 (HNF1 homeobox B (show HNF1B ELISA Kits))-mediated transcription is necessary for fine tuning ATPase Na+/K+ transporting gamma 1 polypeptide (FXYD2 (show FXYD2 ELISA Kits)) transcription in the distal convoluted tubule

  3. Pcbd1 is a moonlighting protein that has dehydratase activity in addition to functioning as a cofactor which regulates HNF1alpha (show HNF1A ELISA Kits).

  4. variants of the hepatocyte nuclear factor-1beta (HNF-1beta / TCF2 (show HNF1B ELISA Kits)) and the dimerization cofactor of HNF-1 (DcoH/PCBD) genes in relation to type 2 diabetes mellitus and beta-cell function

  5. Data reveal DCoH/HNF-1 alpha (show HNF1A ELISA Kits) expression and transcriptional activity in human epidermal melanocytes in vitro and in situ and identified tyrosinase (show TYR ELISA Kits), the key enzyme for pigmentation, as a new transcriptional target.

  6. Albumin (show ALB ELISA Kits) colocalized together with its transcription factor PCD/DCoH/HNF-1alpha (show HNF1A ELISA Kits) in suprabasal keratinocytes in human full-thickness skin sections and in keratinocytes cultured in serum-free medium.

  7. Properties of dehydratase/DCoHalpha are consistent with hypothesis that activity of this isozyme could account for relatively mild symptoms reported for patients with a defect in dehydratase/DCoH

PCBD1 Antigen Profile

Antigen Summary

This gene encodes pterin-4 alpha-carbinolamine dehydratase, an enzyme involved in phenylalanine hydroxylation. A deficiency of this enzyme leads to hyperphenylalaninemia. The enzyme regulates the homodimerization of the transcription factor hepatocyte nuclear factor 1 (HNF1).

Gene names and symbols associated with PCBD1

  • pterin-4a-carbinolamine dehydratase (Pcd) antibody
  • 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) (pcbd1) antibody
  • pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (pcbd1) antibody
  • pterin-4-alpha-carbinolamine dehydratase (Tb11.02.4890) antibody
  • pterin-4-alpha-carbinolamine dehydratase (pcbd) antibody
  • pterin-4-alpha-carbinolamine dehydratase (Fbal_2579) antibody
  • pterin-4-alpha-carbinolamine dehydratase (Ftrac_2004) antibody
  • pterin-4-alpha-carbinolamine dehydratase (Celal_2911) antibody
  • pterin-4-alpha-carbinolamine dehydratase (Isop_1133) antibody
  • pterin-4-alpha-carbinolamine dehydratase (Celly_0291) antibody
  • pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1 (Pcbd1) antibody
  • pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (PCBD1) antibody
  • pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (Pcbd1) antibody
  • BcDNA:LP07248 antibody
  • CG1963 antibody
  • DCoH antibody
  • DDBDRAFT_0204977 antibody
  • DDBDRAFT_0305045 antibody
  • DDB_0204977 antibody
  • DDB_0305045 antibody
  • Dmel\\CG1963 antibody
  • PCBD antibody
  • pcd antibody
  • PHS antibody
  • TCF1 antibody
  • Xdcoh antibody
  • zgc:73389 antibody

Protein level used designations for PCBD1

CG1963-PA , Pcd-PA , pterin-4-alpha-carbinolamine dehydratase , 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) , 4-alpha-hydroxy-tetrahydropterin dehydratase , PCD , PHS , dimerization cofactor of HNF1 , dimerization cofactor of hepatocyte nuclear factor 1-alpha , dimerization cofactor of hepatocyte nuclear factor-1-alpha , phenylalanine hydroxylase-stimulating protein , pterin carbinolamine dehydratase , DCoH , XDCoH , 6-pyruvoyl-tetrahydropterin synthase , cDcoH , pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) , dimerizing cofactor for HNF1 , pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1

GENE ID SPECIES
43499 Drosophila melanogaster
393787 Danio rerio
496425 Xenopus (Silurana) tropicalis
3665797 Trypanosoma brucei brucei strain 927/4 GUTat10.1
8623790 Dictyostelium discoideum AX4
9771410 Ferrimonas balearica DSM 9799
10012150 Marivirga tractuosa DSM 4126
10145334 Cellulophaga algicola DSM 14237
10155246 Isosphaera pallida ATCC 43644
10262275 Cellulophaga lytica DSM 7489
13180 Mus musculus
397951 Xenopus laevis
395729 Gallus gallus
5092 Homo sapiens
530736 Bos taurus
29700 Rattus norvegicus
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