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Regulates the dimerization of homeodomain protein HNF-1- alpha and enhances its transcriptional activity. Additionally we are shipping PCBD2 Antibodies (12) and PCBD2 Proteins (5) and many more products for this protein.
Deletion of intestinal SIRT1 (show SIRT1 ELISA Kits) impairs DCoH2-HNF-1alpha (show HNF1A ELISA Kits)-FXR (show NR1H4 ELISA Kits) signaling and alters systemic bile acid homeostasis.
HNF1alpha (show HNF1A ELISA Kits) binding kinetics may distinguish regulation by DCoH2, under thermodynamic control, from regulation by DCoH (show PCBD1 ELISA Kits), under kinetic control
PMID: 12646162 concludes Alu repeats interfere with splicing of DCOHM and CAVL such that transcripts containing exons of both genes exist.
Regulates the dimerization of homeodomain protein HNF-1- alpha and enhances its transcriptional activity. Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2 (By similarity).
4-alpha-hydroxy-tetrahydropterin dehydratase 2
, HNF-1-alpha dimerization cofactor
, PHS 2
, dcoH-like protein DCoHm
, dimerization cofactor of hepatocyte nuclear factor 1 (HNF1) from muscle
, dimerization cofactor of hepatocyte nuclear factor 1 from muscle
, pterin-4-alpha-carbinolamine dehydratase 2
, 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2
, DcoH-like protein DCoHm
, dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1)
, pterin-4 alpha-carbinolamine dehydratase 2
, hepatocyte nuclear factor 1a dimerization cofactor isoform