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anti-Pumilio Homolog 1 (Drosophila) (PUM1) Antibodies

PUM1 encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. Additionally we are shipping Pumilio Homolog 1 (Drosophila) Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PUM1 80912 Q80U78
PUM1 362609  
PUM1 9698 Q14671
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Top anti-Pumilio Homolog 1 (Drosophila) Antibodies at antibodies-online.com

Showing 10 out of 62 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p) 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded humanbrain tissue reacted with Phospho-PUM1-Y83.ctrl antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of PUM1 (arrow) using PUM1 Antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PUM1 gene (Lane 2) 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human testis tissue reacted with PUM1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of PUM1 (arrow) using rabbit polyclonal PUM1 Antibody 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of PUM1 (arrow) using PUM1 Antibody (Y83) (ABIN391822). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the PUM1 gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded humanbrain tissue reacted with Phospho-PUM1-Y83.ctrl antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of PUM1 (Human N-term) (ABIN392129) in HL-60 cell line lysates (35 µg/lane). PUM1 (arrow) was detected using the purified polyclonal antibody.(2 µg/mL) Formalin-fixed and paraffin-embedded human testis tissue reacted with PUM1 Antibody (N-term) (ABIN392129), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated GS, IP, WB Western Blot analysis of human Pumilio 1, using ABIN151726. Sample: RIPA extract (10 ug) from HeLa cells (CIP, calf intestinal phosphatase). 100 μL Log in to see 5 to 7 Days
$477.75
Details
Fruit Fly Goat Un-conjugated IP, WB 50 μg Log in to see 6 to 8 Days
$434.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-Pumilio 1 Polyclonal Antibody, Unconjugated (ABIN1387238) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Goat Un-conjugated IP, WB 50 μg Log in to see 8 to 10 Days
$522.50
Details
Human Rabbit Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

PUM1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)
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Rat (Rattus)


Human , , ,
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Top referenced anti-Pumilio Homolog 1 (Drosophila) Antibodies

  1. Human Polyclonal PUM1 Primary Antibody for EIA, IHC (p) - ABIN360015 : Spik, Oczkowski, Olszak, Kotecki, Formanowicz, B?azewicz, Jaruzelska: Candidate mRNAs interacting with fertility protein PUMILIO2 in the human germ line. in Reproductive biology 2006 (PubMed)
    Show all 3 references for ABIN360015

  2. Human Polyclonal PUM1 Primary Antibody for EIA, IHC (p) - ABIN359732 : Gupta, Nair, Wharton, Aggarwal: Structures of human Pumilio with noncognate RNAs reveal molecular mechanisms for binding promiscuity. in Structure (London, England : 1993) 2008 (PubMed)
    Show all 2 references for ABIN359732

  3. Human Polyclonal PUM1 Primary Antibody for EIA, IHC (p) - ABIN359733 : Spassov, Jurecic: The PUF family of RNA-binding proteins: does evolutionarily conserved structure equal conserved function? in IUBMB life 2003 (PubMed)
    Show all 2 references for ABIN359733

More Antibodies against Pumilio Homolog 1 (Drosophila) Interaction Partners

Mouse (Murine) Pumilio Homolog 1 (Drosophila) (PUM1) interaction partners

  1. Data indicate a role for RNA-binding protein Pum1 in early embryonic development.

  2. The RNA-binding protein PUMILIO1 (PUM1) not only directly regulates ATAXIN1 (show ATXN1 Antibodies) but also plays an unexpectedly important role in neuronal function. Loss of Pum1 caused progressive motor dysfunction and SCA1 (show ATXN1 Antibodies)-like neurodegeneration with motor impairment, primarily by increasing Ataxin1 (show ATXN1 Antibodies) levels.

  3. Key components of the p53 (show TP53 Antibodies) pathway are coordinately regulated by Pumilio 1 at the posttranscriptional level, which may exemplify an RNA operon.

  4. In (show NME1 Antibodies)mice, puf-A expression was detected primarily in retinal ganglion and pigmented cells.

Human Pumilio Homolog 1 (Drosophila) (PUM1) interaction partners

  1. Pumilios (including PUM1 and PUM2 (show PUM2 Antibodies)) are RNA-binding proteins with Puf domains made up of 8 poorly conserved Puf repeats, 3 helix bundles arranged in rainbow architecture, where each repeat recognizes a single base of the RNA-binding sequence. [REVIEW]

  2. Identification of NORAD-interacting proteins revealed that this lncRNA functions as a multivalent binding platform for PUM (show MYOD1 Antibodies) proteins, with the capacity to sequester a significant fraction of the total cellular pool of PUM1 and PUM2 (show PUM2 Antibodies).Studies reveal unanticipated roles for a lncRNA and PUMILIO proteins in the maintenance of genomic stability.

  3. PUM repeats have now been identified in proteins that function in pre-rRNA processing, including human Puf-A and yeast Puf6.

  4. The promoting effect of hPuf-A in tumorigenesis might be correlated with the regulation of its associated mRNAs.

  5. MED15 (show MED15 Antibodies) and PUM1 proteins with coiled-coil domains are potent enhancers of polyQ-mediated ataxin-1 (show ATXN1 Antibodies) protein misfolding and proteotoxicity in vitro and in vivo.

  6. human Pumilio homologs Pum 1 and Pum 2 repress the translation of E2F3 by binding to the E2F3 3' untranslated region (UTR) and also enhance the activity of multiple E2F3 targeting microRNAs (miRNAs)

  7. Three distinct modes of target RNA binding by PUM1 around the fifth mRNA base were observed.

  8. Pumilio-1 (PUM1) is a ubiquitously expressed RBP (show RBP4 Antibodies) that was shown to interact with p27 (show PAK2 Antibodies)-3' UTR (show UTS2R Antibodies).

  9. The reference genes of choice when performing RT-qPCR on normal and malignant breast specimens should be either the collected group of 3 genes (TBP (show TBP Antibodies), RPLP0 (show RPLP0 Antibodies) and PUM1) employed as an average, or PUM1 as a single gene.

  10. Description of the structures of hPum Puf domain complexed to two noncognate RNAs, CycB (show CCNB1 Antibodies)(reverse) and Puf5.

Pumilio Homolog 1 (Drosophila) (PUM1) Antigen Profile

Protein Summary

This gene encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of the encoded protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with PUM1

  • pumilio homolog 1 (Drosophila) (pum1) antibody
  • pumilio homolog 1 (Drosophila) (PUM1) antibody
  • pumilio 1 (Drosophila) (Pum1) antibody
  • pumilio homolog 1 (Drosophila) (Pum1) antibody
  • pumilio RNA-binding family member 1 (PUM1) antibody
  • AA517475 antibody
  • DKFZp459K0627 antibody
  • fb96a03 antibody
  • HSPUM antibody
  • mKIAA0099 antibody
  • PUM1 antibody
  • PUMH antibody
  • PUMH1 antibody
  • pumilio1 antibody
  • PUML1 antibody
  • Pumm antibody
  • si:ch211-285e16.1 antibody
  • wu:fb96a03 antibody
  • wu:fb96a08 antibody
  • zgc:63671 antibody

Protein level used designations for PUM1

pumilio homolog 1 , pumilio homolog 1 (Drosophila) , pumilio-1 , pumilio 1

GENE ID SPECIES
394176 Danio rerio
100174674 Pongo abelii
100135847 Oncorhynchus mykiss
80912 Mus musculus
419554 Gallus gallus
362609 Rattus norvegicus
9698 Homo sapiens
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