You are viewing an incomplete version of our website. Please click to reload the website as full version.

Purine-Rich Element Binding Protein B Proteins (PURB)

PURB product is a sequence-specific, single-stranded DNA-binding protein. Additionally we are shipping Purine-Rich Element Binding Protein B Antibodies (29) and Purine-Rich Element Binding Protein B Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PURB 498407 Q68A21
PURB 19291 O35295
PURB 5814 Q96QR8
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Purine-Rich Element Binding Protein B Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$2,784.83
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,839.83
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$388.93
Details

PURB Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Mouse (Murine)

Human

More Proteins for Purine-Rich Element Binding Protein B (PURB) Interaction Partners

Mouse (Murine) Purine-Rich Element Binding Protein B (PURB) interaction partners

  1. This structural arrangement suggests that the cooperative assembly of the dimeric Purbeta repressor on the sense strand of the ACTA2 (show ACTA2 Proteins) enhancer is dictated by the association of each subdomain with distinct purine-rich binding sites within the enhancer.

  2. These findings suggest that the highly conserved modular repeats of Purbeta fold to form a core functional domain, which mediates the specific and high affinity binding of the protein to single-stranded DNA.

  3. Overexpression of Purbeta, but not Puralpha (show PURA Proteins), significantly downregulated GnRH1 (show GNRH1 Proteins) mRNA levels in transiently transfected GT1 (show MYL4 Proteins)-7 cells, suggesting that Purbeta acts as a repressor of GnRH1 (show GNRH1 Proteins) gene transcription.

  4. Purbeta is a single-stranded DNA-binding repressor of vascular smooth muscle alpha-actin (show ACTA2 Proteins) gene transcription

  5. analysis of of DNA binding and localized strand separation by Pur alpha (show PURA Proteins) and comparison with Pur beta

  6. Pur alpha (show PURA Proteins) and Pur beta repress smooth muscle alpha-actin (show ACTA2 Proteins) gene transcription by means of DNA strand-selective cis (show CISH Proteins)-element binding and cell type-dependent protein-protein interactions

  7. analysis of the quaternary structure of recombinant mouse Purbeta

  8. These data demonstrate that Pur proteins collaborate with Sp3 to regulate a transcriptional program that enables muscle cells to remodel their phenotype.

  9. structural role for certain core arginine residues in forming a conformationally stable Pur beta protein capable of physical interactions necessary for smooth muscle alpha-actin (show ACTA2 Proteins) gene repression.

  10. Activation of the normally silent SM alpha A gene in reprogrammed adult cardiomyocytes is linked to elevated interaction of serum response factor with Pur-alpha (show PURA Proteins)/Pur-beta.

Human Purine-Rich Element Binding Protein B (PURB) interaction partners

  1. Suggest dynamic interplay between transcriptional activators Pur-alpha (show PURA Proteins)/Pur-beta and repressors in regulating SMalphaA (show ACTA2 Proteins) gene output during myofibroblast differentiation.

  2. results show that PUR proteins are capable of binding to alpha-MHC (show MYH6 Proteins) mRNA and attenuate its translational efficiency; also show robust expression of PUR proteins in failing hearts where alpha-MHC (show MYH6 Proteins) mRNA levels are suppressed

  3. findings offer insights into mechanism, energetics, and sequence of Purbeta repressor binding to a biologically relevant, contractile phenotype-regulating cis (show CISH Proteins)-element while revealing the thermodynamic confines of Purbeta-mediated effects on DNA structure

Purine-Rich Element Binding Protein B (PURB) Protein Profile

Protein Summary

This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.

Gene names and symbols associated with PURB

  • purine rich element binding protein B (Purb)
  • purine-rich element binding protein B (purb-a)
  • purine-rich element binding protein B (PURB)
  • purine-rich element binding protein Bb (purbb)
  • 2310015K15Rik protein
  • AA114818 protein
  • Cager-2 protein
  • D11Bwg0414e protein
  • pur-beta protein
  • purb protein
  • purb-b protein
  • PURBETA protein
  • zgc:65916 protein

Protein level used designations for PURB

purine-rich element-binding protein B , transcription factor Pur-beta , transcriptional activator protein Pur-beta , PurB beta , purine-rich single-stranded DNA-binding protein beta , vascular actin single-stranded DNA-binding factor 2 p44 component , purine-rich element-binding protein B-B , transcriptional activator protein Pur-beta-B , purine-rich element binding protein B

GENE ID SPECIES
498407 Rattus norvegicus
19291 Mus musculus
373775 Xenopus laevis
5814 Homo sapiens
393519 Danio rerio
Selected quality suppliers for Purine-Rich Element Binding Protein B Proteins (PURB)
Did you look for something else?