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anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 4 (P2RX4) Antibodies

The product of P2RX4 belongs to the family of purinoceptors for ATP. Additionally we are shipping P2RX4 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
P2RX4 18438  
P2RX4 29659 P51577
P2RX4 5025 Q99571
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Top anti-P2RX4 Antibodies at antibodies-online.com

Showing 10 out of 57 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Goat Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated ELISA, WB ABIN334455 (0.3µg/ml) staining of Human Kidney lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated WB Anti- P2RX4 antibody, Western blotting All lanes: Anti P2RX4  at 0.5ug/ml Lane 1: MCF-7Whole Cell Lysate at 40ug Lane 2: COLO320 Whole Cell Lysate at 40ug Predicted bind size: 43 KD Observed bind size: 77KD 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated WB Anti- P2RX4 Picoband antibody, Western blotting All lanes: Anti P2RX4  at 0.5ug/ml WB: Recombinant Human P2RX4 Protein 0.5ng Predicted bind size: 39KD Observed bind size: 39KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Cow Goat Un-conjugated EIA, WB AP31932PU-N P2RX4 antibody staining of Human Kidney lysate at 1 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated FACS, WB Western Blot analysis of P2RX4 expression in transfected 293T cell line by P2RX4 MaxPab polyclonal antibody.Lane 1: P2RX4 transfected lysate(42.68 KDa).Lane 2: Non-transfected lysate. FACS analysis of negative control 293 cells (Black) and P2RX4 expressing 293 cells (Green) using P2RX4 purified MaxPab mouse polyclonal antibody. 50 μg Log in to see 9 Days
$430.00
Details
Mouse Goat Un-conjugated IHC (p), ELISA, WB Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details

P2RX4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)
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Rat (Rattus)
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Human
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Top referenced anti-P2RX4 Antibodies

  1. Human Polyclonal P2RX4 Primary Antibody for ELISA, WB - ABIN334455 : Yeung, Kharidia, Brown, Gorecki: Enhanced expression of the P2X4 receptor in Duchenne muscular dystrophy correlates with macrophage invasion. in Neurobiology of disease 2004 (PubMed)
    Show all 3 references for ABIN334455

  2. Cow (Bovine) Polyclonal P2RX4 Primary Antibody for EIA, WB - ABIN375223 : Yuan, Zhu, Zhou, Chen, Zhu, Ma, He, Tian, Shi: Role of mast cell activation in inducing microglial cells to release neurotrophin. in Journal of neuroscience research 2010 (PubMed)
    Show all 2 references for ABIN375223

  3. Human Polyclonal P2RX4 Primary Antibody for FACS, WB - ABIN518564 : Bornø, Ploug, Bune, Rosenmeier, Thaning: Purinergic receptors expressed in human skeletal muscle fibres. in Purinergic signalling 2012 (PubMed)

  4. Chicken Polyclonal P2RX4 Primary Antibody for WB - ABIN2776331 : Dubyak: Go it alone no more--P2X7 joins the society of heteromeric ATP-gated receptor channels. in Molecular pharmacology 2007 (PubMed)

More Antibodies against P2RX4 Interaction Partners

Mouse (Murine) Purinergic Receptor P2X, Ligand-Gated Ion Channel, 4 (P2RX4) interaction partners

  1. IRF5 (show IRF5 Antibodies) expression in microglia is regulated by IRF8 (show IRF8 Antibodies). IRF5 (show IRF5 Antibodies) directly upregulates P2rX4 expression on microglia in peripheral nerve injury, and may play a role in neuropathic pain.

  2. Specific localization of the P2X4 receptor subunit was evaluated in mouse, rat and cat retinae using fluorescence immunohistochemistry and pre-embedding immuno-electron microscopy

  3. P2X4 receptors contribute to ethanol intake and indicate that there is a complex interaction between P2X4 receptors and ethanol.

  4. Loss of P2X4 expression is associated with exaggerated renal fibrosis following unilateral ureteric obstruction.

  5. There is a protective role for endogenous cardiac myocyte P2X4R in heart failure. It is demonstrated in a physical interaction between the myocyte receptor and eNOS (show NOS3 Antibodies).

  6. Our previous and current findings, combined with our preliminary evidence of increased ethanol consumption in P2X4R knockout mice, suggest that the ethanol and IVM action pocket in P2X4Rs formed by positions 42, 46, 331, and 336.

  7. The hippocampus was partially protected from status epilepticus-induced neuronal death in P2X4R-deficient mice compared with wild-type animals.

  8. Data suggest that P2X4 is expressed in majority of myenteric neurons, contributes to membrane currents activated by ATP, and plays important role in cell signaling as subunit of purinergic P2X receptor/channel.

  9. co-expression of P2X4 receptor with P2X7 receptor (show P2RX7 Antibodies) in dendritic cells leads to enhancement of inflammation through facilitation of P2X7 (show P2RX7 Antibodies)-dependent release of pro-inflammatory cytokines.

  10. P2X4 receptors play a role in parotid gland function (especially under conditions where sympathetic stimulation occurs concurrently) and are a potential target for salivary hypofunction diseases

Human Purinergic Receptor P2X, Ligand-Gated Ion Channel, 4 (P2RX4) interaction partners

  1. These findings provide new insights in understanding the contribution of the salt bridge between Asp (show ASIP Antibodies)-85 and Arg-309 and its structurally coupled beta2,3-sheet to the function of P2X4 receptors.

  2. The results suggest a role of PrP(C (show PRNP Antibodies)) in proteostasis, dysfunctions of which may be involved in the pathogenesis of neurodegenerative diseases such as TSE and Alzheimer's Disease.

  3. Fndings support role for P2X7 (show P2RX7 Antibodies) and P2X4 coupled to induction of inflammatory molecules in modulating high glucose and palmitate-induced endothelial cell activation and dysfunction.

  4. These data suggest that vascular smooth muscle cells from human gastro-omental arteries express P2X1 (show P2RX1 Antibodies) and P2X4 receptor subunits

  5. This study demonstrates a major physiological finding that the shear-induced effects on endothelial KLF2 (show KLF2 Antibodies) axis are in part dependent on ATP release and P2X4, a previously unidentified mechanism.

  6. Using pHluorin, P2X4 was found to be expressed on the plasma membrane and within subcellular compartments in hippocampus.

  7. It appears to mediate the cells' response to extracellular ATP. Although Ca2thorn influx via P2X1 receptor (show P2RX1 Antibodies) is necessary for alpha-synuclein (show SNCA Antibodies) accumulation.

  8. P2X4 and calmodulin (show CALM1 Antibodies) form a complex at endolysosomal membrane where P2X4 activation recruits calmodulin (show CALM1 Antibodies) to promote fusion and vacuolation in a Ca(2 (show CA2 Antibodies)+)-dependent fashion.

  9. the lysosome-localized P2X4 may play specific roles in membrane trafficking of acidic organelles in mammalian cells.

  10. P2X4 assembles with P2X7 (show P2RX7 Antibodies) and pannexin-1 (show PANX1 Antibodies) in gingival epithelial cells and modulates ATP-induced reactive oxygen species production and inflammasome activation during P. gingivalis infection.

Xenopus laevis Purinergic Receptor P2X, Ligand-Gated Ion Channel, 4 (P2RX4) interaction partners

  1. The renal epithelial Na channel is stimulated by P2Xreceptor activation; the stimulation is dependent on increases in intracellular Ca(2 (show CA2 Antibodies)) and phosphatidylinositol 3-kinase activation.

  2. A point mutation in ectodomain-transmembrane 2 of P2X4 receptor significantly reduces ethanol's inhibitory effects.

Zebrafish Purinergic Receptor P2X, Ligand-Gated Ion Channel, 4 (P2RX4) interaction partners

  1. ATP-recognition of P2X4 receptors

  2. a property that is essential for purinergic sensory signaling. Apo (show C9orf3 Antibodies) and ATP-bound X-ray structures of the detergent-solubilized zebrafish P2X4 receptor provide a blueprint for receptor mechanisms

  3. crystal structure of the zebrafish P2X4 receptor in complex with ATP and a new structure of the apo (show C9orf3 Antibodies) receptor

  4. Cloning and characterization of zebrafish P2X4 and P2X5 (show P2RX5 Antibodies).

  5. Comparison of the acid-sensing ion channel (show ACCN2 Antibodies) structure with the ATP-gated P2X(4) receptor reveals similarity in pore architecture and aqueous vestibules

P2RX4 Antigen Profile

Protein Summary

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest sensitivity for these antagonists. Multiple alternatively spliced transcript variants, some protein-coding and some not protein-coding, have been found for this gene.

Gene names and symbols associated with P2RX4

  • purinergic receptor P2X, ligand-gated ion channel, 4 (P2RX4) antibody
  • purinergic receptor P2X, ligand-gated ion channel 4 (P2rx4) antibody
  • purinergic receptor P2X, ligand-gated ion channel, 4 (p2rx4) antibody
  • purinergic receptor P2X, ligand-gated ion channel, 4a (p2rx4a) antibody
  • AI504491 antibody
  • AW555605 antibody
  • D5Ertd444e antibody
  • p2rx4 antibody
  • p2x4 antibody
  • p2x4r antibody
  • wu:fi03f02 antibody

Protein level used designations for P2RX4

purinergic receptor P2X4 , purinergic receptor P2X, ligand-gated ion channel, 4 , p2X purinoceptor 4-like , ATP receptor , P2X purinoceptor 4 , ionotropic purinergic receptor , P2X4 , ATP-gated cation channel protein , P2X receptor, subunit 4 , purinoceptor P2X4 , P2X4 purinoceptor , ATP-gated ion channel subunit P2X4 , etID14865.21 , zP2X4.1

GENE ID SPECIES
452319 Pan troglodytes
100059626 Equus caballus
100458831 Pongo abelii
100589361 Nomascus leucogenys
18438 Mus musculus
29659 Rattus norvegicus
338036 Bos taurus
5025 Homo sapiens
448783 Canis lupus familiaris
398206 Xenopus laevis
374166 Gallus gallus
259258 Danio rerio
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