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anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) Antibodies

The product of P2RX7 belongs to the family of purinoceptors for ATP. Additionally we are shipping P2RX7 Kits (12) and P2RX7 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
P2RX7 5027 Q99572
P2RX7 18439 Q9Z1M0
P2RX7 29665 Q64663
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Top anti-P2RX7 Antibodies at antibodies-online.com

Showing 10 out of 95 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-P2RX7 Antibody  Positive Control: Lane 1:541 µg mock transfected HEK-293Lane 2: 041 µg hP2X7 transfected HEK-293Lane 3: 041 µg mP2X7 transfected HEK-293Lane 4: 041 µg rP2X7 transfected HEK-293 Primary Antibody Dilution: 1:025Secondary Antibody: Anti-rabbit-HRPSecondry  Antibody Dilution: 1:0000Submitted by: Ronald Sluyter, School of Biological Sciences, University of Wollongong 100 μL Log in to see 2 to 3 Days
$289.00
Details
Dog Goat Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated IHC (p), WB P2RX7 Antibody (C-term) (ABIN651861) western blot analysis in MDA-MB435 cell line and mouse kidney tissue lysates (15 µg/lane). This demonstrates the P2RX7 antibody detected the P2RX7 protein (arrow). P2RX7 Antibody (C-term) (ABIN651861) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-P2RX7 Antibody Titration: 1.25ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-P2RX7 Antibody  Positive Control: Lane 1:541 µg mock transfected HEK-293Lane 2: 041 µg hP2X7 transfected HEK-293Lane 3: 041 µg mP2X7 transfected HEK-293Lane 4: 041 µg rP2X7 transfected HEK-293 Primary Antibody Dilution: 1:025Secondary Antibody: Anti-rabbit-HRPSecondry  Antibody Dilution: 1:0000Submitted by: Ronald Sluyter, School of Biological Sciences, University of Wollongong 100 μL Log in to see 2 to 3 Days
$289.00
Details
Rat Rabbit Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated WB Anti-P2RX7 antibody, Western blotting WB: U87 Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Goat Un-conjugated IHC, ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB   100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC (p), WB WB Image P2X7 antibody detects P2X7 protein by western blot analysis. Rat tissue extracts (50 μg) was separated by 7.5% SDS-PAGE, and the membrane was blotted with P2X7 antibody , diluted at 1:3000. IHC-P Image Immunohistochemical analysis of paraffin-embedded human breast cancer, using P2X7, antibody at 1:250 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details

P2RX7 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-P2RX7 Antibodies

  1. Human Polyclonal P2RX7 Primary Antibody for IHC (p), WB - ABIN651861 : Kim, Jiang, Wilson, North, Surprenant: Proteomic and functional evidence for a P2X7 receptor signalling complex. in The EMBO journal 2001 (PubMed)
    Show all 2 references for ABIN651861

  2. Human Polyclonal P2RX7 Primary Antibody for IF (p), IHC (p) - ABIN1386314 : Peng, Liu, Wei, Lv, Wang, Xiong, Wang, Altaf, Wang, He, Wang, Qu: P2X7R is involved in the progression of atherosclerosis by promoting NLRP3 inflammasome activation. in International journal of molecular medicine 2015 (PubMed)

  3. Dog (Canine) Polyclonal P2RX7 Primary Antibody for WB - ABIN2776151 : Al-Shukaili, Al-Kaabi, Hassan: A comparative study of interleukin-1beta production and p2x7 expression after ATP stimulation by peripheral blood mononuclear cells isolated from rheumatoid arthritis patients and normal healthy controls. in Inflammation 2008 (PubMed)

  4. Cow (Bovine) Polyclonal P2RX7 Primary Antibody for IHC, WB - ABIN2776335 : Buell, Talabot, Gos, Lorenz, Lai, Morris, Antonarakis: Gene structure and chromosomal localization of the human P2X7 receptor. in Receptors & channels 1999 (PubMed)

  5. Dog (Canine) Polyclonal P2RX7 Primary Antibody for EIA, IHC (p) - ABIN401660 : Tomasinsig, Pizzirani, Skerlavaj, Pellegatti, Gulinelli, Tossi, Di Virgilio, Zanetti: The human cathelicidin LL-37 modulates the activities of the P2X7 receptor in a structure-dependent manner. in The Journal of biological chemistry 2008 (PubMed)

More Antibodies against P2RX7 Interaction Partners

Zebrafish Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) interaction partners

  1. Blockade of the P2X7 receptor reduces cyst formation via ERK (show MAPK1 Antibodies)-dependent pathways in a zebrafish model of polycystic kidney disease.

Human Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) interaction partners

  1. these data indicate that activation of EGFR (show EGFR Antibodies) enhanced the expression of P2X7R in neuroblastoma (show ARHGEF16 Antibodies) cells lacking trophic support, being PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies)/PKC (show PRRT2 Antibodies) signaling pathway and Sp1 (show PSG1 Antibodies) mediating this pro-survival outcome

  2. Result suggest the positive correlation between purinergic receptor P2X 7 (P2X7R) and T-complex protein 1 (TCP-1) in lymphoma patients.

  3. A gain-of-function mutation in P2X7R associated with autoimmune disease caused enhanced TG2 (show TGM2 Antibodies) externalization from cells, and this correlated with increased pore activity.

  4. pancreatic ductal adenocarcinoma cell lines overexpress P2X7R and the receptor plays crucial roles in cell survival, migration and invasion.

  5. P2X7 SNPs, 1513A>C and -762T>C, may be associated with the susceptibility to tuberculosis.

  6. Report association between elevated expression of P2X7 receptor in monocytes and high serum CRP (show CRP Antibodies) and cytokine levels in type 2 diabetics.

  7. The altered function and expression of P2X7 and ART1 (show ART1 Antibodies) in the human CD39 (show ENTPD1 Antibodies)+ Treg or CD39 (show ENTPD1 Antibodies)- Treg cells could participate in the resistance against cell death induced by ATP or NAD.

  8. signaling through purinergic receptors, particularly P2X7R, drives an adaptive Th17 response in human visceral adipose tissue underlying the metabolic changes in obesity.

  9. This chapter describes structural features of P2X7, chemical properties of its agonist, antagonist, and allosteric modulators and summarizes recent advances on P2X7 receptor as therapeutic target in the aforementioned diseases

  10. High P2X7R expression is a good prognostic factor for glioma radiosensitivity and survival probability in humans.

Cow (Bovine) Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) interaction partners

  1. For the inflammasome-dependent IL-1beta (show IL1B Antibodies) release, bovine monocytes require ATP in addition to a primary stimulus. This IL-1beta (show IL1B Antibodies) release depends on potassium efflux, but, in contrast to human and murine monocytes, does not require calcium influx or generation of reaction oxygen and is independent of the P2X7 receptor.

Mouse (Murine) Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) interaction partners

  1. Activation of P2X7 by ATP induced the release of TNFalpha (show TNF Antibodies) from microglia which protected neurons from NMDA-induced excitotoxicity, might also account for neuroprotective properties of valproic acid

  2. Data provide mechanistic insights into the role of KHG26792 in the inhibition of TNF-alpha (show TNF Antibodies) produced via purinergic receptor P2X7 receptor-mediated activation of NFAT (show NFATC1 Antibodies) and MAPK (show MAPK1 Antibodies) pathways in adenosine triphosphate-treated BV-2 cells.

  3. Results suggest that P2X7R is an important activator of the immune response that leads to type 1 diabetes.

  4. P2X7R plays a role in the neuroinflammation in a model of mania.

  5. Data show that T-complex protein 1 (TCP-1) may be a crucial downstream molecule of purinergic receptor P2X 7 (P2X7R) and plays a role in lymphoid neoplasm metastasis.

  6. IL-17 (show IL17A Antibodies) production in the hearts of M2AChR mice is dependent on P2x7 expression in dilated cardiomyopathy.

  7. unveiled the critical role of adenosine triphosphate-P2X7 receptor (ATP-P2X7R)in brain damage in radiation-induced brain injury (RBI), suggesting that inhibition of ATP-P2X7R axis might be a potential strategy for the treatment of patients with RBI.

  8. High P2X7R expression is a good prognostic factor for glioma radiosensitivity and survival probability.

  9. P2X7 is a protective factor and therapeutic target for the amelioration of hyperoxia-induced lung injury.

  10. Neutrophils express functional cell-surface P2X7R, which leads to ATP-induced loss of intracellular K(+), NLRP3 (show NLRP3 Antibodies) inflammasome activation and IL-1beta (show IL1B Antibodies) secretion.

P2RX7 Antigen Profile

Protein Summary

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria.

Gene names and symbols associated with P2RX7

  • purinergic receptor P2X, ligand-gated ion channel, 7 (P2RX7) antibody
  • purinergic receptor P2X, ligand-gated ion channel, 7 (p2rx7) antibody
  • purinergic receptor P2X, ligand-gated ion channel, 7 (P2rx7) antibody
  • AI467586 antibody
  • P2RX7 antibody
  • P2X(7) antibody
  • p2x7 antibody
  • P2X7R antibody
  • p2xr7 antibody

Protein level used designations for P2RX7

P2X purinoceptor 7 , purinergic receptor P2X, ligand-gated ion channel, 7 , p2X purinoceptor 7-like , ATP receptor , P2X7 receptor , P2Z receptor , purinergic receptor P2X7 variant A , P2X7 purinoceptor , purinergic receptor P2X7

GENE ID SPECIES
100058464 Equus caballus
387298 Danio rerio
452318 Pan troglodytes
699455 Macaca mulatta
771952 Gallus gallus
100458463 Pongo abelii
100588362 Nomascus leucogenys
5027 Homo sapiens
448778 Canis lupus familiaris
286814 Bos taurus
18439 Mus musculus
29665 Rattus norvegicus
497623 Sus scrofa
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